Akamatsu Industries, who attempts to kill his co-workers on several occasions after contracting Algernon. He reprograms various types of machines and robots to attack his former friends, which results in the battles of the first several episodes. After being apprehended, he is later killed and used to grow an Animus Flower by BPL. - The head scientist of BPL, who took part in the Dive Inspection several years ago. Although his laboratory is said to be developing new food sources, he is actually developing various biological monsters, which he uses to attack Mode Warp and Akamatsu Industries' employees. His biological creatures, which range from massive beasts to killer insects, are the primary threat of much of the first half of the series. He is killed during the protagonists' attempt to attack his lab when one of his own creations, which has gained self will, turns on him. - A powerful psychic, and the leader of the Superhuman Federation. His attempts to harness Kaede's powers are the main threat faced by the protagonists in the second half of the series. Mamon is a survivor of the Dive Inspection who still hopes to create a superior human being through psychic powers. He eventually does harness Kaede's powers long enough to transform himself into the powerful Brahman, though he still falls to Lamia during the final battle of the series. - A mysterious, incredibly powerful being, which appears as a somewhat effeminate, shadow-like creature. It is the unexpected result of the Dive Inspection, made up entirely of cancerous cells. As such, it seeks to consume all other life and assimilate it into itself, beginning with the Bettermen, which it recognizes as its biggest threat. It is Lamia's ultimate goal to defeat this creature, which he manages to do only by transforming into the ultimate Betterman, OLTUS. , the name of which itself derives from the book "Flowers for Algernon", is never completely understood until the final moments of the series. Even then, it is left to the viewer to deduce what Algernon exactly is. Algernon seems to be, as mentioned, either a virus, or a sort of mutation. Victims of Algernon show symptoms like those in the end chapters of "Flowers for Algernon," (loss of intellect and emotional control) but on a larger, more violent scale. Rage isn't the only symptom, as insanity and bodily mutation are evident in many cases. Betterman's Transformations