HMB may refer to: Compounds β-Hydroxy β-methylbutyric acid, , a metabolite of the essential amino acid leucine, synthesized in the human body Human Melanoma Black, a monoclonal antibody Languages Humburi Senni language, spoken in Burkina Faso and Mali Places Half Moon Bay, California, city in the United States Sports Historical medieval battles, a modern sport Other Hawkeye Marching Band, the marching band for the University of Iowa HabibMetro, a Swiss multinational bank in Pakistan Heavy menstrual bleeding, a menstrual condition Host Memory Buffer, an optional feature in version 1.2 of the NVMe specification, which allows SSDs to utilize the DRAM of the host machine His/Her Magesty's Barque