prevented these molecular pathologies. P300 inhibition has shown to inhibit the deleterious effects of DUX4 BET inhibitors have been shown to reduce DUX4 expression. Antioxidants could potentially reduce the effects of FSHD. One study found that vitamin C, vitamin E, zinc gluconate, and selenomethionine supplementation increased endurance and strength of the quadriceps, but had no significant benefit on walking performance. Further study is warranted. Outcome measures Ways of measuring the disease are important for studying disease progression and assessing the efficacy of drugs in clinical trials. Quality of life can be measured with questionnaires, such as the FSHD Health Index. How the disease affects daily activities can measured with questionnaires, such as the FSHD‐Rasch‐built overall disability scale (FSHD-RODS) or FSHD composite outcome measure (FSHD-COM). Electrical impedance myography is being studied as a way to measure muscle damage. Muscle MRI is useful for assessment of all the muscles in the body. Muscles can be scored based on the degree of fat infiltration. References External links World FSHD Alliance: FSHD patient advocacy organizations across the world list of clinical trials for FSHD, Clinicaltrials.gov. Muscular dystrophy Rare diseases Articles containing video clips