and adsorbs both pepsin and bile acids. It has been thought that sucralfate also stimulates the production of prostaglandin E2, epidermal growth factors (EGF), bFGF, and gastric mucus. Pharmacokinetics Onset: 1-2 hr (initial onset for peptic ulcer disease (PUD)) Absorption: <5% Orally Duration: Up to 6 hours due to high affinity for defective mucosa (PUD) Bioavailability: 5%, sucralfate is considered non-systemic, sucrose octasulfate: 5%, aluminum:0.005% Metabolism: Not metabolized, excreted unchanged in urine Excretion: Primarily in feces as unchanged drug Brand names Brand names include Carafate in U.S.A., Sucramal in Italy, Sucrafil, Sufrate, Sucralpro, Sucralcoat, Pepsigard, Sucral, Hapifate, Sucralpro in India, Sutra or Musin in parts of South-East Asia, Sulcrate in Canada, Discral (sucralfato) in México, Ulsanic in South Africa and Israel, Andapsin in Sweden and Antepsin. Sucracell in India. References External links Drugs acting on the gastrointestinal system and metabolism Equine medications Disaccharides AbbVie brands Aluminium compounds Wikipedia medicine articles ready to translate Sulfate esters ru:Противоязвенные препараты и препараты для лечения гастроэзофагеального рефлюкса#Сукралфат