distribution were consistent with those of developing oligodendrocytes. Independently, Stallcup and colleagues generated an antiserum that recognized a group of rat brain tumor cell lines, which exhibited properties that were intermediate between those of typical neurons and glial cells. Biochemical studies showed that the antiserum recognized a chondroitin sulfate proteoglycan with a core glycoprotein of 300 kDa, and the antigen was named NG2 (nerve/glial antigen 2). NG2 was found to be expressed on A2B5+ oligodendrocyte precursor cells isolated from the perinatal rat CNS tissues and on process-bearing cells in the CNS in vivo. Comparison of NG2 and Pdgfra expression revealed that NG2 and PDGFRA are expressed on the same population of cells in the CNS. These cells represent 2-9% of all the cells and remain proliferative in the mature CNS. See also List of human cell types derived from the germ layers References External links Nervous tissue cells Glial cells