young actors shared a small studio apartment, and began their careers on the stage. Early career O'Brien spent a decade in plays on Broadway and in the New York City area. O'Brien made his film debut in the Vitaphone Varieties short film, The Nightingale, produced in New York and released in August 1930. His first starring role was as ace reporter Hildy Johnson in the original 1931 version of The Front Page with Adolphe Menjou. In 2010, this film was selected by the National Film Preservation Board for preservation in the Library of Congress's National Film Registry as being "culturally, historically, or aesthetically significant." He was the lead in Paramount's Personal Maid (1931), and appeared in a Metro-Goldwyn-Mayer musical Flying High (1931), supporting Bert Lahr. He was Irene Dunne's love interest in RKO's Consolation Marriage (1932), then co-starred opposite a young Bette Davis in Hell's House (1932). O'Brien stayed in leads, going from studio to studio: Scandal for Sale (1932), at Universal; The Strange Case of Clara Deane (1932), at Paramount; Hollywood Speaks (1932), American Madness (1932) and Virtue (1932). O'Brien played a heroic pilot in Universal's Air Mail (1932), directed by John Ford. While at that studio he was in the compelling Laughter in Hell (1932) and Destination Unknown (1933). At the small Majestic Pictures he starred in The World Gone Mad (1933). Warner Bros O'Brien's first Warner Bros. movie was Bureau of Missing Persons (1933), starring Bette Davis. He went to RKO for Flaming Gold (1933) and MGM for Bombshell (1933), then Warners signed O'Brien to a long-term contract. He would remain with the studio until 1940, when he left after a dispute over the terms of his contract renewal. O'Brien supported Dick Powell in College Coach (1933) and Joan Blondell in I've Got Your Number (1934). He was third lead to Barbra Stanwyck and Joel McCrea in Gambling Lady (1934), then was with Powell again in Twenty Million Sweethearts (1934). Here Comes the Navy (1934) was O'Brien's first film with James Cagney, also under contract to Warners. The two originally met in 1926 and remained friends for almost six decades. After O'Brien's death, Cagney referred to him as his "dearest friend." O'Brien played the lead, a boxer, in The Personality Kid (1934), supported Powell in Flirtation Walk (1934) and was an auctioneer in I Sell Anything (1935). Cagney and O'Brien were reteamed in Devil Dogs of the