the Protection of Human Subjects (see: Human subject research legislation in the United States) enacted in 1977 remained in place: 45CFR § 46.204(d), "No application or proposal involving human in vitro fertilization may be funded by the Department or any component thereof until the application or proposal has been reviewed by the Ethical Advisory Board and the Board has rendered advice as to its acceptability from an ethical standpoint." Since there was no Ethics Advisory Board, federally funded research was not possible. See also Stem cell controversy References Bioethics Cloning Stem cells United States federal health legislation 1995 in American law