highly problematic due to academic freedom in case of universities and regulatory capture in case of government-funded R&D. Conflict of Interest Disclosure of potential conflicts of interest (COIs) is used by journals to guarantee credibility and transparency of the scientific process. Conflict of interest disclosure, however, is not systematically nor consistently dealt with by journals that publish scientific research results. When research is funded by the same agency that can be expected to gain from a favorable outcome there is a potential for biased results and research shows that results are indeed more favorable than would be expected from a more objective view of the evidence. A 2003 systematic review studied the scope and impact of industry sponsorship in biomedical research. The researchers found financial relationships among industry, scientific investigators, and academic institutions widespread. Results showed a statistically significant association between industry sponsorship and pro-industry conclusions and concluded that "Conflicts of interest arising from these ties can influence biomedical research in important ways". A British study found that a majority of the members on national and food policy committees receive funding from food companies. In an effort to cut costs, the pharmaceutical industry has turned to the use of private, nonacademic research groups (i.e., contract research organizations [CROs]) which can do the work for less money than academic investigators. In 2001 CROs came under criticism when the editors of 12 major scientific journals issued a joint editorial, published in each journal, on the control over clinical trials exerted by sponsors, particularly targeting the use of contracts which allow sponsors to review the studies prior to publication and withhold publication of any studies in which their product did poorly. They further criticized the trial methodology stating that researchers are frequently restricted from contributing to the trial design, accessing the raw data, and interpreting the results. The Cochrane Collaboration, a worldwide group that aims to provide compiled scientific evidence to aid well informed health care decisions, conducts systematic reviews of randomized controlled trials of health care interventions and tries to disseminate the results and conclusions derived from them. A few more recent reviews have also studied the results of non-randomized, observational studies. The systematic reviews are published in the Cochrane Library. A 2011 study done to disclose possible conflicts of interests in underlying research studies used for medical meta-analyses reviewed 29 meta-analyses and found that conflicts of interest in the studies underlying