Frank Harold Spedding (22 October 1902 – 15 December 1984) was a Canadian American chemist. He was a renowned expert on rare earth elements, and on extraction of metals from minerals. The uranium extraction process helped make it possible for the Manhattan Project to build the first atomic bombs. A graduate of the University of Michigan and University of California, Berkeley, Spedding became an assistant professor and head of the department of physical chemistry at Iowa State College in 1937. His efforts at building up the school were so successful that he would spend the rest of his career there, becoming a professor of chemistry in 1941, a professor of physics in 1950, a professor of metallurgy in 1962, and ultimately professor emeritus in 1973. He co-founded, along with Dr. Harley Wilhelm, the Institute for Atomic Research and the Ames Laboratory of the Atomic Energy Commission, and directed the Ames Laboratory from its founding in 1947 until 1968. Spedding developed an ion-exchange method of separating and purifying rare earth elements using ion-exchange resins, and later used ion exchange to separate isotopes of individual elements, including hundreds of grams of almost pure nitrogen-15. He published over 250 peer-reviewed papers, and held 22 patents in his own name and jointly with others. Some 88 students received their Ph.D. degree under his supervision. Early life and education Spedding was born on 22 October 1902, in Hamilton, Ontario, Canada, the son of Howard Leslie Spedding and Mary Ann Elizabeth (Marshall) Spedding. Soon after he was born, the family moved to Michigan, and then Chicago. He became a naturalized U.S. citizen through his father. The family moved to Ann Arbor, Michigan, where his father worked as a photographer, in 1918. He entered the University of Michigan in 1920, receiving a Bachelor of Science (B.S.) degree in chemical engineering in 1925 and a Master of Science (M.S.) in analytical chemistry the following year. As an undergraduate, Spedding took issue with the prevailing explanation by Friedrich August Kekulé of how the six carbon atoms in benzene hold together and proposed an alternate explanation. His professor, Moses Gomberg, recognised this as being the same as the (incorrect) model advanced by Albert Ladenburg in 1869. At Gomberg's suggestion, Spedding applied to the University of California, Berkeley, to study for his doctorate under Gilbert N. Lewis. Gomberg wrote a recommendation so that Spedding was not only accepted, but given a