discovery of a phosphorylated ester that was known as Harden–Young ester until chemical analysis showed it to be fructose 1,6-bisphosphate. It is now known to be the product of phosphorylating fructose 6-phosphate by the action of phosphofructokinase; it is broken down into glyceraldehyde 3-phosphate and dihydroxyacetone phosphate by the action of aldolase. Personal life Harden married Georgina Sydney Bridge (died January 1928) in 1900 and they had no children. See also William John Young References External links including the Nobel Lecture, 12 December 1929 The Function of Phosphate in Alcoholic Fermentation English biochemists Nobel laureates in Chemistry British Nobel laureates Fellows of the Royal Society Scientists from Manchester 1865 births 1940 deaths People educated at Tettenhall College English Nobel laureates