July 10, 1985, Crowe was appointed by President Ronald Reagan to serve as Chairman of the Joint Chiefs of Staff (CJCS). He continued to serve as CJCS through the Bush administration until 1989, when he retired from active duty. He was the first Chairman of the Joint Chiefs of Staff to serve under the provisions of the Goldwater-Nichols Department of Defense Reorganization Act of 1986, where he as chairman became (not the collegial body of the Joint Chiefs of Staff), by statute, the principal military adviser to the president, the National Security Council, and the Secretary of Defense. In 1989, Army General Colin L. Powell succeeded him as CJCS. Later life and death After he retired in October 1989, Crowe returned to the University of Oklahoma and William J. Crowe chair in geopolitics. Crowe surprised politicians when he endorsed Bill Clinton in the presidential election of 1992. President Clinton named Crowe chairman of the President's Foreign Intelligence Advisory Board in 1993. In 1994, Clinton appointed Crowe the United States Ambassador to the United Kingdom, and he served in that capacity until 1997. Crowe sat on the boards of Texaco, Merrill Lynch, Pfizer, Norfolk Southern Corporation, and General Dynamics. He also served on the board of Emergent BioSolutions (then Bioport), a company that provided controversial anthrax vaccinations to the U.S. military in the 1990s. The deal was approved by the Clinton administration, with which Crowe had a previous relationship. At the time of his death, Crowe served as the chairman of the board of Global Options, Inc., an international risk-management and business solutions company headquartered in Washington, D.C. As he did at the University of Oklahoma in 1990–91, Crowe taught a seminar class on national security at the United States Naval Academy from 2000 to 2007. In 2004, Crowe was among 27 retired diplomats and military commanders called Diplomats and Military Commanders for Change who publicly said the administration of President George W. Bush did not understand the world and was unable to handle "in either style or substance" the responsibilities of global leadership. On June 16, 2004 the former senior diplomats and military commanders issued a statement against the Iraq War. Death Crowe died on October 18, 2007, at Bethesda Naval Hospital in Maryland at age 82 due to a heart condition. His funeral was held on October 31, 2007, at the Naval Academy chapel; Bill Clinton spoke. Crowe was