The Keldysh Institute of Applied Mathematics () is a research institute specializing in computational mathematics. It was established to solve computational tasks related to government programs of nuclear and fusion energy, space research and missile technology. The Institute is a part of the Department of Mathematical Sciences of the Russian Academy of Sciences. The main direction of activity of the institute is the use of computer technology to solve complex scientific and technical issues of practical importance. Since 2016, development of mathematical and computational methods for biological research, as well as a direct solution to the problems of computational biology with the use of such methods, has also been included in the circle of scientific activities of the institute. Scientific activity Nuclear physics Prominent theoretical physicist Yakov Borisovich Zel'dovich headed one of the departments placed in charge of the theoretical aspects of the work on the creation of nuclear and thermonuclear weapons. Young Alexander Andreevich Samarskii performed the first realistic calculations of macrokinetics of chain reaction of a nuclear explosion, which led to the practical importance estimated power of nuclear weapons. In relation to nuclear energy, the institute was also involved in modelling of processes of neutron transport and nuclear reactions. In particular, E. Kuznetsov is known for his work on the theory of nuclear reactors. Currently, such work in KIAM is continuing in the field of plasma physics and controlled thermonuclear fusion, which began under the leadership of S. P. Kurdyumov, , . Cosmonautics D. E. Okhotsimsky directed the works in the department created for researches of dynamics of space flight. In 1966, the department was reorganized into the Ballistic Centre. The Ballistic Centre was involved in the calculations of optimal orbit trajectory and actual corrections for all space flights, from unmanned interplanetary and lunar vehicles to the manned "Soyuz" and orbital station "Salyut" and "Mir". The department also investigated the docking task, controlled landing and stabilizing the spacecraft. The institute took an active part in the creation of the Soviet space shuttle "Buran". KIAM continues to engage in performance of current Russian space projects. The current researches are connected with: development of systems for management and navigation of space vehicles in real time with the use of global satellite navigation systems GPS and GLONASS; studies of the atmosphere of the planets of the solar system; exploration of prospects for further interplanetary missions using electric rocket engines; participation in