M106 or M-106 may refer to: M106 (New York City bus), a New York City Bus route in Manhattan M-106 (Michigan highway), a state highway in Michigan BMW M106, a motor Messier 106, a spiral galaxy about in the constellation Canes Venatici Klimov VK-106 or M-106 aircraft engine M106 mortar carrier a tracked, self-propelled artillery vehicle formerly in service with the United States Army nl:M106