The Hounsfield scale ( ), named after Sir Godfrey Hounsfield, is a quantitative scale for describing radiodensity. It is frequently used in CT scans, where its value is also termed CT number. Definition The Hounsfield unit (HU) scale is a linear transformation of the original linear attenuation coefficient measurement into one in which the radiodensity of distilled water at standard pressure and temperature (STP) is defined as 0 Hounsfield units (HU), while the radiodensity of air at STP is defined as −1000 HU. In a voxel with average linear attenuation coefficient , the corresponding HU value is therefore given by: where and are respectively the linear attenuation coefficients of water and air. Thus, a change of one Hounsfield unit (HU) represents a change of 0.1% of the attenuation coefficient of water since the attenuation coefficient of air is nearly zero. Calibration tests of HU with reference to water and other materials may be done to ensure standardised response. This is particularly important for CT scans used in radiotherapy treatment planning, where HU is converted to electron density. Variation in the measured values of reference materials with known composition, and variation between and within slices may be used as part of test procedures. Rationale The above standards were chosen as they are universally available references and suited to the key application for which computed axial tomography was developed: imaging the internal anatomy of living creatures based on organized water structures and mostly living in air, e.g. humans. Values for different body tissues and material HU-based differentiation of material applies to medical-grade dual-energy CT scans but not to cone beam computed tomography (CBCT) scans, as CBCT scans provide unreliable HU readings. Values reported here are approximations. Different dynamics are reported from one study to another. Exact HU dynamics can vary from one CT acquisition to another due to CT acquisition and reconstruction parameters (kV, filters, reconstruction algorithms, etc.). The use of contrast agents modifies HU as well in some body parts (mainly blood). A practical application of this is in evaluation of tumors, where, for example, an adrenal tumor with a radiodensity of less than 10 HU is rather fatty in composition and almost certainly a benign adrenal adenoma. See also Cone beam computed tomography: Bone density and the Hounsfield scale. References External links Hounsfield Unit - fpnotebook.com Imaging of deep brain stimulation leads using extended Hounsfield unit CT. Stereotact Funct Neurosurg.