given to those who, due to severe and permanent disabilities, need help with basic needs, but also to expand the possibility of an active life despite extensive disabilities. Respite care, a contact family or short-term accommodation are other examples of support measures. Adults Adult women with Aicardi syndrome need continued habilitation efforts and support in daily life. This could be, for example, support and care in a home with special services and daily activities. Prognosis The prognosis varies widely from case to case, depending on the severity of the symptoms. However, almost all people reported with Aicardi syndrome to date have experienced developmental delay of a significant degree, typically resulting in mild to moderate to profound intellectual disability. The age range of the individuals reported with Aicardi syndrome is from birth to the mid-40s. There is no cure for this syndrome. Epidemiology Worldwide prevalence of Aicardi syndrome is estimated at several thousand, with approximately 900 cases reported in the United States. There is no definite information on how common Aicardi syndrome is, but the incidence is estimated to be around one in 100,000 newborns. There may be people who do not have the fully developed syndrome and who have not been diagnosed. History This disorder was first recognized as a distinct syndrome in 1965 by Jean Aicardi, a French pediatric neurologist and epileptologist. References External links GeneReviews/NCBI/NIH/UW entry on Aicardi Syndrome OMIM entries on Aicardi syndrome Neurological disorders Neurological disorders in children X-linked dominant disorders Genetic disorders with OMIM but no gene Syndromes affecting the nervous system Corpus callosum Syndromes with tumors Rare syndromes