Wilson received a telephone call from Dreyer & Reinbold co-owners Robbie Buhl and Dennis Reinbold and visited their workshop in January 2010. He was impressed by what he observed and signed to the team soon after. Wilson mentored his teammate Mike Conway on oval track racing and advised DRR on road courses. In the first four races he finished second at the Grand Prix of St. Petersburg and the Grand Prix of Long Beach. After qualifying 11th for the Indianapolis 500, Wilson led eleven laps and took seventh. Four races later, he took his first IndyCar pole position for the Honda Indy Toronto. The rest of Wilson's season saw him achieve a best of sixth at the Indy Grand Prix of Sonoma. He was 11th in the drivers' standings with 361 points. Although linked with the Andretti Autosport, KV Racing Technology and Panther Racing teams for the 2011 season, Wilson stayed at DRR. An important factor in his decision was the progress he believed the team had made in 2010. Wilson sustained a minor fracture in his left wrist in an accident with Alex Tagliani at the season-opening Grand Prix of St. Petersburg and wore a carbon fibre brace. He started the Indianapolis 500 from 19th position. Handling and balance difficulties left Wilson in 16th. His best finish of 2011 was fifth at Edmonton Indy. During practice for the Honda Indy 200 an accident left him with a stable burst fracture of the T5 vertebrae in his back. Wilson was ruled unfit for three months and wore a back brace. For the rest of the season, his substitutes were Simon Pagenaud at Mid-Ohio, Tomas Scheckter at New Hampshire Motor Speedway, Giorgio Pantano on the road and street courses and Townsend Bell in Kentucky and Las Vegas. Wilson was 24th in the points standings with 183. For the 2012 season, he returned to drive for DCR in its No. 18 Dallara DW12-Honda car. Wilson had two tenth-place finishes in the first four races. At the Indianapolis 500, he qualified in 21st and finished 7th. At the Firestone 550 Wilson overtook Graham Rahal, who crashed with two laps to go, for his third career series victory and his first on an oval track. The rest of his season saw him claim two more top-ten results in the final eight races for 15th in the drivers' championship with 278 points. Wilson remained at