engineer cells for useful characteristics. For teaching Because of their rapid generation times microbes offer an opportunity to study microevolution in the classroom. A number of exercises involving bacteria and yeast teach concepts ranging from the evolution of resistance to the evolution of multicellularity. With the advent of next-generation sequencing technology it has become possible for students to conduct an evolutionary experiment, sequence the evolved genomes, and to analyze and interpret the results. See also Artificial selection Bacteriophage experimental evolution Directed evolution Domestication Evolutionary biology Evolutionary physiology Genetics Genomics of domestication Laboratory experiments of speciation Quantitative genetics Selective breeding Tame Silver Fox References Further reading External links E. coli Long-term Experimental Evolution Project Site , Lenski lab, Michigan State University A movie illustrating the dramatic differences in wheel-running behavior. Experimental Evolution Publications by Ted Garland: Artificial Selection for High Voluntary Wheel-Running Behavior in House Mice — a detailed list of publications. Experimental Evolution — a list of laboratories that study experimental evolution. Network for Experimental Research on Evolution, University of California. New Scientist article on domestication by selection Inquiry-based middle school lesson plan: "Born to Run: Artificial Selection Lab" Digital Evolution for Education software Evolutionary biology Biology experiments