to kidnap Michael Kramer, a man carrying a fatal experimental disease, in order to release it on America. The Viper battled the first Spider-Woman, and became convinced that she was Merriam Drew. Drew was the mother of Spider-Woman and was considered deceased since 1931. The issue revealed Merriam had become allied to Chthon and was granted longevity in return. The Viper revealed herself to have been a pawn of Chthon for 50 years, but saved Spider-Woman's life by defying Chthon. Viper, employing Constrictor as her chief operative, captured Spider-Woman, believing she was responsible for making her think they were related. It was revealed that Chthon had actually granted Viper false memories of mothering Jessica as part of a plan to place both women under his control. Viper captured Captain America, and planned to release her new bubonic plague. Whether Viper actually has extraordinary longevity was left uncertain. Re-employing the Silver Samurai, Viper attempted to coerce Team America into stealing the Cavourite Crystal, and then battled the New Mutants. In one of her many terrorist acts, she would try to gain control of the snake-themed organization called the Serpent Society, with Slither, Copperhead, Puff Adder, Fer-De-Lance, and Black Racer as her operatives. The latter four operatives infiltrated the Serpent Society in an attempt to take it over. Viper dispatched Cobra, Boomslang, and Copperhead to poison Washington D.C.'s water supply with a snake mutagen. Viper terrorized the White House and the President, and battled Captain America. She attempted to assassinate the organization's former leader Sidewinder, but she was betrayed by Cobra and arrested by Captain America. Viper was later freed from prison by Tyrannus. She used a snake mutagen on drug addicts, and then battled the Punisher. She then turned against and battled Tyrannus. Madame Hydra has also been in conflict with the X-Men. She first came into contact with them upon trying to assassinate Mariko Yashida on behalf of her ally and presumed lover Silver Samurai, and tried to poison the team while disguised as Mariko's unconscious maid. She nearly killed X-Men members Rogue and Storm on two separate occasions, with Storm being nearly killed by Viper during the invasion of Khan. She also faced the New Mutants and was considered responsible for the presumed demise of Karma (Karma was only wounded and was abducted by the Shadow King for his own reasons). Madame Hydra is a professional terrorist and has