ticks. His Micrographia, published in 1665, included illustrations and written descriptions of the things he saw under the microscope. Others also worked with the microscope following its acceptance as a scientific tool. Francesco Redi, an Italian physician and naturalist, used a microscope for observation of invertebrates, but is known for his work in disproving the theory of spontaneous generation. Redi managed to prove that flies did not spontaneously arise from rotting meat. He conducted controlled experiments and detailed observation of the fly life cycle in order to do so. Redi also worked in the description and illustration of parasites for both plants and animals. Other men were also conducting research into pests and parasites at this time. Felix Plater, a Swiss physician, worked to differentiate between two types of tape worm. He also wrote descriptions of both the worms he observed and the effects these worms had on their hosts. Following the publication of Francis Bacon's ideas about the value of experimentation in the sciences came a shift toward true experimental efforts in the biological sciences, including invertebrate zoology. Jan Swammerdam, a Dutch microscopist, supported an effort to work for a 'modern' science over blind belief in the work of ancient philosophers. He worked—like Redi—to disprove spontaneous generation using experimental techniques. Swammerdam also made a number of advancements in the study of anatomy and physiology. In the field of entomology, he conducted a number of dissections of insects and made detailed observations of the internal structures of these specimens. Swammerdam also worked on a classification of insects based on life histories; he managed to contribute to the literature proving that an egg, larva, pupa, and adult are indeed the same individual. 18th and 19th centuries In the 18th century, the study of invertebrates focused on the naming of species that were relevant to economic pursuits, such as agricultural pests. Entomology was changing in big ways very quickly, as many naturalists and zoologists were working with hexapods. Work was also being done in the realm of parasitology and the study of worms. A French physician named Nicolas Andry de Bois-Regard determined that worms were the cause of some diseases. He also declared that worms do not spontaneously form within the animal or human gut; de Bois-Regard stated that there must be some kind of 'seed' which enters the body and contains the worm in some form. Antonio Vallisneri also worked with