HFE may refer to: HFE (gene), a gene that encodes the Human hemochromatosis protein H-parameter model (hFE), the current gain of a bipolar junction transistor Health First Europe Hefei Luogang International Airport, in Anhui, China, now defunct Hefei Xinqiao International Airport, in Anhui, China Hello from Earth, an interstellar radio message Herschend Family Entertainment Corporation, an American entertainment company Hertford East railway station, in England Hidden Field Equations, a cryptosystem Horizontal Fiscal Equalisation, in Australia Human factors engineering Hydrofluoroether, a solvent