Zayn al-Din Sayyed Isma‘il ibn Husayn Gorgani (c. 1040–1136), also spelled al-Jurjani, was a Persian 12th century royal Islamic physician from Gorgan, Iran. In addition to medical and pharmaceutical sciences, he was also an adept in theological, philosophic, and ethical sciences. Jurjani was a pupil of Ibn Abi Sadiq and Ahmad ibn Farrokh. He arrived at the court in the Persian province of Khwarazm in the year 1110 when he was already a septuagenarian. There he became a court physician to the governor of the province, Khwarazm-Shah Qutb al-Din Muhammad I, who ruled from 1097 to 1127. It was to him that he dedicated his most comprehensive and influential work, the Persian-language compendium Zakhirah-i Khvarazm'Shahi. Jurjani continued as court physician to Khwarazm'Shah Qutb al-Din's son and successor, Ala al-Din Atsiz, until at some unspecified time he moved to the city of Merv, the capital of the rival Seljuq Sultan Sanjar (ruled 1118–1157), where he died nearly at 100 lunar years of age. Jurjani composed a number of important medical and philosophical treatises, in both Persian and Arabic, most of them written after he moved to Khwarazm at the age of 70 lunar years. Thesaurus of the Shah of Khwarazm Al-Jurjani wrote the Persian medical encyclopedia, Thesaurus of the Shah of Khwarazm (also known as The Treasure of Khwarazm Shah), sometime after 1110, when he moved to the northern Persian province of Khwarezm. Much of his work was dependent on Avicenna's The Canon of Medicine (c. 1025), along with al-Jurjani's own ideas not found in the Canon. The work is composed of ten volumes covering ten medical fields: anatomy, physiology, hygiene, diagnosis and prognosis, fevers, diseases particular to a part of the body, surgery, skin diseases, poisons and antidotes, and medicaments (both simple and compound). In endocrinology , in particular, al-Jurjani was one of "the first to associate exophthalmos with goitre," which was not repeated until Caleb Parry (1755–1822) in 1825, and later by Robert James Graves (1796–1853) and Carl von Basedow (1799–1854). Al-Jurjani also established an association between goitre and palpitation. On "Drugs recommended for lice control," Gorgani recommends the following method: Most of the above botanicals have recently been shown to possess especially insecticidal properties. Works Some of his works are: Zakhireh-i Kharazmshahi, a ten volume encyclopedia of medical sciences Khafi Alayee, a summary of Zakhireh-i Kharazmshahi Al-Iqraz al-Tebbieh and Al-Mabahis al-Alaieh, Tib Yadegar Kitab-fi-Hifz al-Sihat (Book on Preserving