While in Italy, Hutten had become imbued with a fierce hatred for the papacy, which he bitterly attacked in his preface to an edition of Laurentius Valla's De Donatione Constantini, published in 1517. He thus helped prepare the way for Martin Luther. In 1518, Hutten accompanied his patron, Archbishop Albert, on several official journeys to Paris and to the Diet of Augsburg, where Luther had his famous conference with Thomas Cajetan. Subsequently, Hutten established a small printing press, and published pamphlets written in the German language attacking the Pope and the Roman clergy. Participation in the Reformation Archbishop of Mainz Albrecht von Brandenburg denounced him at Rome, whereupon in 1519 Hutten became a supporter of Luther and his calls for religious reform. Unlike Luther, Hutten tried to enforce reformation by military means when he, along with Franz von Sickingen attempted to begin popular crusade within the Holy Roman Empire against the power of the Roman Catholic Church in favour of Luther's reformed religion. In what is known as the Knights' Revolt, they attacked the lands of the Archbishop of Trier in 1522. The archbishop held out, however, and the knights were eventually defeated in 1523, destroying them as a significant political force within the empire. Following his defeat, Hutten tried to convince Erasmus of Rotterdam to side with the Reformation. Erasmus refused to take sides, and he also refused to see Hutten when the latter came to Basel in 1523, ill and impoverished, to see him. Their estrangement culminated in a literary quarrel between the two humanists. Hutten's Ulrichi ab Hutten cum Erasmo Rotirodamo, Presbytero, Theologo, Expostulatio is a collection of his arguments against Erasmus; it was printed by Johannes Schott from Strasbourg in 1523. It contains a woodcut of Hutten and Erasmus; it was thought (in 1850) to be the earliest known woodcut of the latter. Hutten died in seclusion on the island of Ufenau on Lake Zurich. Health issues For the final 15 years of his life, Hutten suffered from the "French disease" (or syphilis), of which he died. He wrote a text in 1519, De morbo Gallico (On the French disease), about the symptoms of what is thought to be syphilis and its treatment with Guaiacum. His text is regarded as one of the first patient narratives in the history of medicine; Holbein the Younger's portrait of him from 1523 is the first known realistic portrait of