Film and television Perlman started his career as a stage actor, appearing in various productions, and made his feature film debut in Jean-Jacques Annaud's film Quest for Fire (1981). Annaud later revealed that when he contacted Perlman to ask him about playing Salvatore in The Name of the Rose (1986), Perlman was thinking of abandoning his career. After various minor and supporting roles in films and television series, his breakthrough role came when he played Vincent on the television series Beauty and the Beast, opposite Linda Hamilton, from 1987 to 1990. This earned him a Golden Globe Award for Best Performance by an Actor in a Television Series in 1989. He went on to play roles in many films and television series throughout the 1980s and 1990s as well as the 2000s. His most notable film appearances were in films such as The Name of the Rose (1986), Romeo is Bleeding (1993), The Adventures of Huck Finn (1993), Police Academy: Mission to Moscow (1994), The Last Supper (1995), The Island of Dr. Moreau (1996), Alien Resurrection (1997), Enemy at the Gates (2001), Blade II and Star Trek: Nemesis (both 2002) and two Stephen King adaptations, Sleepwalkers and Desperation. His appearances on television series include Highlander: The Series, The Outer Limits, The Magnificent Seven, and the Amazon series Hand of God. He played his first leading film role in 1995, when he played "One" in Jean-Pierre Jeunet and Marc Caro's French-language The City of Lost Children. In 2003, Perlman starred in a commercial for Stella Artois beer. This commercial, which was called "Devil's Island", won a Silver Award at the 2003 British Advertising Awards. He got another leading film role in 2004 when he played the title role in the comic book adaptation Hellboy. Perlman reprised his role as Hellboy in the straight to DVD animated features Hellboy: Sword of Storms (2006) and Hellboy: Blood and Iron (2007) as well as Hellboy II: The Golden Army, released on July 11, 2008. In 2008, Perlman joined the cast of the television series Sons of Anarchy on FX playing Clay Morrow, the national president of the Sons of Anarchy Motorcycle Club. He also played Wes Chandler in the second and third seasons of StartUp in 2017–18. In 2022 Perlman starred in Steven Brand's noir thriller Joe Baby alongside Dichen Lachman, Willa Fitzgerald and Harvey Keitel. Voice-over work Perlman also has a successful career