healing in post traumatic stress disorder. Due to the permissive action of cortisol on glucagon, partial blockade of cortisol may reduce the effects of circulating glucagon in chronically increasing blood glucose in metabolic syndrome (syndrome X) and type 2 diabetes. See also ACTH stimulation test References 3β-Hydroxysteroid dehydrogenase inhibitors 11β-Hydroxylase inhibitors 21-Hydroxylase inhibitors Aldosterone synthase inhibitors Antiglucocorticoids 3-Pyridyl compounds