"Once in a Lifetime" is a song by the American new wave band Talking Heads, produced and cowritten by Brian Eno. It was released in November 1980 as the lead single from Talking Heads' fourth studio album, Remain in Light (1980), through Sire Records. Eno and Talking Heads developed "Once in a Lifetime" through extensive jams, inspired by Afrobeat musicians such as Fela Kuti. David Byrne's vocals were inspired by preachers delivering sermons, with lyrics addressing existential crisis and the unconscious. The music video, directed by Byrne and Toni Basil, has Byrne dancing erratically over footage of religious rituals. "Once in a Lifetime" was certified gold in the UK in 2021. A live version, taken from the 1984 concert film Stop Making Sense, charted in 1986 on the Billboard Hot 100. NPR named "Once in a Lifetime" one of the 100 most important American musical works of the 20th century. The Rock and Roll Hall of Fame lists it as one of the "500 Songs that Shaped Rock and Roll", and Rolling Stone ranked it at number 27 on its 2021 list of "The 500 Greatest Songs of All Time". The music video has been named among the greatest by several publications. Production Like other songs on Remain in Light, Talking Heads and producer Brian Eno developed "Once in a Lifetime" by recording jams, isolating the best parts, and learning to play them repetitively. Songwriter Robert Palmer joined the jam on guitar and percussion. The technique was influenced by early hip hop and the Afrobeat music of artists such as Fela Kuti, which Eno had introduced to the band. Singer David Byrne likened the process to modern looping and sampling, describing the band as "human samplers". He said the song was a result of the band trying and failing to play funk, inadvertently creating something new instead. The track was initially not one of Eno's favorites, and the band almost abandoned it. According to keyboardist Jerry Harrison, "Because there were so few chord changes, and everything was in a sort of trance ... it became harder to write defined choruses." However, Byrne had faith in the song and felt he could write lyrics to it. Eno developed the chorus melody by singing wordlessly, and the song "fell into place". Harrison developed the "bubbly" synthesizer line and added the Hammond organ climax, taken from the Velvet Underground's "What Goes On". Eno