Indira (1983). In 2000, she made her adult debut in the Bengali film Ek Je Aachhe Kanya, in which she played a negative character. It was followed by a role in Rituparno Ghosh's acclaimed film Titli, opposite Mithun Chakraborty and her mother Aparna Sen. In 2001, she starred in the English-language film Mr. and Mrs. Iyer, directed by Aparna Sen. The film performed well mainly in multiplexes and was a major critical success. Sen Sharma's performance as a Tamil housewife and her mastery of the accent were received well and she was awarded the National Film Award for Best Actress. Her performance was later included in the 2010 issue of the "Top 80 Iconic Performances" by Filmfare. This was followed by the National Film Award-winning social film, Page 3 (2005). Her role of a smart journalist drew praise and she became a more familiar face to the movie-going public. Sen Sharma was offered the lead role in Mira Nair's Hollywood film, The Namesake (2007), but owing to clashing dates with other films, she could not commit to the project. However, she followed it with acclaimed performances as a mentally ill woman in 15 Park Avenue (2005) and as a middle aged village woman in Omkara (2006). For the latter, she received both the Filmfare Awards for Best Supporting Actress and the National Film Award for Best Supporting Actress. Her next release Deadline: Sirf 24 Ghante (2006) got average reviews. In 2006, Sen Sharma made her directorial debut with an 18-minute Bengali short film titled Naamkoron (Naming Ceremony) for the Kala Ghoda Film Festival. Following this, Sen Sharma acted in Dosar, a Bengali art film by Rituporno Ghosh which was premiered at several international film festivals. She won the Best Actress award at Mahindra Indo-American Arts Council (MIAAC) Film Festival for her performance. Her first release of 2007 was her second collaboration with Madhur Bhandarkar, a noir film named Traffic Signal, in which she played a street prostitute. Later that year, she appeared in Anurag Basu's Life in a... Metro. The film opened to positive reviews and performed well at the Indian box office. Metro depicted the lives of different individuals in Mumbai, and Sen Sharma's performance as a young and insecure woman earned her a second Filmfare Award for Best Supporting Actress. In late 2007, Sen Sharma acted in 2 films under the Yash Raj Films banner. She noted her