Missile Crisis broke. Ingersoll sailed with an amphibious group to the Canal Zone in case additional troops were needed in the emergency. When the sea blockade coupled with diplomacy resulted in the removal of the missile threat, she resumed training out of San Diego. She returned to the Far East in October 1963 to support carrier operations in the East and South China Seas and resumed operations out of San Diego in the spring of 1964. Vietnam WarIngersoll completed a yard overhaul 5 February 1965, conducted readiness operations along the seaboard, then sailed from San Diego 9 June 1965 for the coast of South Vietnam. Her duty were mainly Market Time patrols to intercept Viet Cong men and supplies, but she was also called upon for 24 gunfire missions against 116 targets along the Vietnamese coast, and 3 missions 12 km up the Saigon River. She operated with the aircraft carriers for plane guard and screen duties, including and . She returned to San Diego 23 November 1965 for a much deserved leave and upkeep period extending through 31 December.Ingersoll completed yard overhaul 5 February 1965 and immediately began training for a WestPac deployment. She sailed for the Far East 9 June and on 5 July 1965 began coastal surveillance patrols. On the 20th she joined the naval gunfire support group off the coast of Quang Ngai. On 10 October she was assigned to plane guard duty in the South China Sea. On 4 November she headed home and arrived at San Diego on 23 November 1965. Ingersoll operated along the West Coast until departing San Diego 5 November 1966 for the Far East. Upon reaching the war zone she participated in Operation Sea Dragon, anti-shipping and interdiction operations, and plane guard duty for . On 5 December, a North Vietnamese coastal battery fired on the destroyer whose counter fire silenced the enemy guns. Ingersoll continued to operate in the war zone and other Oriental waters until returning home in the spring of 1967. The ship was deployed for her final deployment in 1968 to the Vietnamese coast where her task was to interdict materiel and supplies headed from North Vietnam to South Vietnam. This would mark the last time her guns were fired in anger. For service during the Korean and Vietnam eras, Ingersoll'' and eligible personnel earned the Europe bar for the previously awarded Navy Occupation Medal, the