has appointed no new titular bishop to these Eastern sees since the Second Vatican Council. After the Battle of Manzikert in 1071, with the Byzantine Empire was in civil chaos, the Seljuks took Tralles for the first time but Alexios I Komnenos re-captured the city for Byzantium in the later half of the eleventh century. By the 13th century, the city lay in ruins. In 1278, Andronikos II Palaiologos decided to rebuild and repopulate it, now to be renamed Andronikopolis or Palaiologopolis, with the aim of forming a bulwark against Turkish encroachment in the area. The megas domestikos Michael Tarchaneiotes was given the task: he rebuilt the walls and settled 36,000 people from the surrounding regions. 13th century Byzantine settlement policy along the Meander Valley notably involved the Turkic Cumans. Nevertheless, Turkish attacks resumed soon after. The city was besieged and, lacking sufficient supplies and access to water, captured by the beylik of Menteshe in 1284. The city suffered extensive destruction and part of its inhabitants were massacred. Moreover, over 20,000 inhabitants were sold off as slaves. Turkic and Ottoman era Under the rule of Menteshe, whose lands extended towards the south, the city was renamed as Güzelhisar ("beautiful castle"). The city was later taken over by the Aydinids, who made it one of their principal settlements, but not the capital. The Beylik of Aydin was founded in the region in 1307 and they ruled the lands north of Büyük Menderes River up to and including İzmir. During the first half of the 14th century, Aydinids were as active as the Ottomans, if not more, in pressuring the islands and the lands west of Anatolia, and they caused much hardship for the Byzantine and Latin dependencies of the Aegean Sea and mainland Greece. The principality was taken over by the rising Ottoman Empire, for the first time shortly before the Battle of Ankara between the Ottomans and Tamerlane in 1402, and then Tamerlane having given back the province to the sons of Aydın. Finally Ottomans definitely captured it in 1425. Aydın became part of Anatolia Province of the Ottoman Empire and this until 1827, when it became the seat of its own eyalet under its own name, constituted among other reasons to respond to the prevalent unrest in the region, as exemplified by Atçalı Kel Mehmet Rebellion (1829–1830). The seat was moved to İzmir in the 1840s and with the