| TKO (knee and punches) | UFC 180 | | align=center| 2 | align=center| 2:27 | Mexico City, Mexico | |- | Win | align=center| 18–5–1 | Travis Browne | Decision (unanimous) | UFC on Fox: Werdum vs. Browne | | align=center| 5 | align=center| 5:00 | Orlando, Florida, United States | |- | Win | align=center| 17–5–1 | Antônio Rodrigo Nogueira | Submission (armbar) | UFC on Fuel TV: Nogueira vs. Werdum | | align=center| 2 | align=center| 2:41 | Fortaleza, Brazil | |- | Win | align=center| 16–5–1 | Mike Russow | TKO (punches) | UFC 147 | | align=center| 1 | align=center| 2:28 | Belo Horizonte, Brazil | |- | Win | align=center| 15–5–1 | Roy Nelson | Decision (unanimous) | UFC 143 | | align=center| 3 | align=center| 5:00 | Las Vegas, Nevada, United States | |- | Loss | align=center| 14–5–1 | Alistair Overeem | Decision (unanimous) | Strikeforce: Overeem vs. Werdum | | align=center| 3 | align=center| 5:00 | Dallas, Texas, United States | |- | Win | align=center| 14–4–1 | Fedor Emelianenko | Submission (triangle armbar) | Strikeforce: Fedor vs. Werdum | | align=center| 1 | align=center| 1:09 | San Jose, California, United States | |- | Win | align=center| 13–4–1 | Antônio Silva | Decision (unanimous) | Strikeforce: Fedor vs. Rogers | | align=center| 3 | align=center| 5:00 | Hoffman Estates, Illinois, United States | |- | Win | align=center| 12–4–1 | Mike Kyle | Submission (guillotine choke) | Strikeforce: Carano vs. Cyborg | | align=center| 1 | align=center| 1:24 | San Jose, California, United States | |- | Loss | align=center| 11–4–1 | Junior dos Santos | TKO (punches) | UFC 90 | | align=center| 1 | align=center| 1:20 | Rosemont, Illinois, United States | |- | Win | align=center| 11–3–1 | Brandon Vera | TKO (punches) | UFC 85 | | align=center| 1 | align=center| 4:40 | London, England | |- | Win | align=center| | Gabriel Gonzaga | TKO (punches) | UFC 80 | | align=center| 2 | align=center| 4:34 | Newcastle upon Tyne, England | |- | Loss | align=center| 9–3–1 | Andrei Arlovski | Decision (unanimous) | UFC 70 | | align=center| 3 | align=center| 5:00 | Manchester, England | |- | Win | align=center| 9–2–1 | Alexander Emelianenko | Submission (arm-triangle choke) | 2H2H: Pride & Honor | | align=center| 1 | align=center| 3:24 | Rotterdam,