is not so severe Do not usually develop cirrhosis Usually show muscle weakness and hypotonia Survive into adulthood Life expectancy varies upon symptom severity Childhood neuromuscular type Develops in late childhood Has myopathy and dilated cardiomyopathy Varies greatly Some have mild muscle weakness Some have severe cardiomyopathy and die in early adulthood Diagnosis An assay of amylo-1,4 → 1,6 glucan transferases (which removes a block of 6 glucose residues from the 1,4 position and attaches it to the 1,6 position of the same chain) Alternative names and related disease Alternative names in medical literature for the disease include: Andersen's triad Glycogenosis type IV Glycogen branching enzyme deficiency Polyglucosan body disease Amylopectinosis Mutations in GBE1 can also cause a milder disease in adults that is called adult polyglucosan body disease. In other mammals The form in horses is known as glycogen branching enzyme deficiency. It has been reported in American Quarter Horses and related breeds. The disease has been reported in the Norwegian Forest Cat, where it causes skeletal muscle, heart, and CNS degeneration in animals greater than five months old. It has not been associated with cirrhosis or liver failure. References External links Inborn errors of carbohydrate metabolism Hepatology