in Hulk and the Agents of S.M.A.S.H., voiced by Jeffrey Combs. This version is a gaming A.I. created by Iron Man that gained sentience. In the episode "Wheels of Fury", he threatened to destroy a city if Iron Man lost his real-life game, which Mainframe merely saw as continuing Iron Man's challenge as ordered. In response, the agents of S.M.A.S.H. went up against Mainframe's robots in a roller derby. After the agents of S.M.A.S.H. and Iron Man defeat Mainframe's robots, Mainframe is persuaded not to attack the city. Desiring to learn more about the real world, Mainframe creates a new body and leaves to see the world. In the episode "Planet Monster" Pt. 2, Mainframe is among several heroes who help the agents of S.M.A.S.H. and the Avengers fight the Supreme Intelligence's forces. Collected editions References External links A-Next issue reviews. Avengers (comics) Marvel Comics 2