Mutation. In Marvel Avengers Academy, Oscorp take the symbiotes from their home world, forcing Spider-Man to try and save them. However, the symbiotes are bonded to various hosts and attempt to take over the Academy. While they fail to do so, they decide to remain on Earth. The symbiotes appear in Marvel vs. Capcom Infinite. In the game's story, Jedah Dohma uses the Soul Stone to steal a million souls from Earth and feed them to a Giant Symbiote, planning to strengthen it and use it as a weapon against Ultron Sigma. He also gives pieces of the symbiote to A.I.M.brella to bond to virus-infected subjects to stabilize them. Spider-Man, Chris Redfield, Frank West, and Mike Haggar defeat Jedah, but he unleashes the creature on New Metro City. When Redfield tries attacking it, he accidentally causes part of the symbiote to bond to Spider-Man, forcing the latter to fight his teammates against his will until Frank uses car alarms to remove the symbiote. After getting three of the Infinity Stones, the heroes destroy the creature. Venom also appears as a playable character via downloadable content. Marvel's Spider-Man game series The Venom symbiote is featured throughout the Marvel's Spider-Man series developed by Insomniac Games. In this universe, New York City mayor Norman Osborn had obtained the symbiote some time prior to the events of the first game, and is using it as an experimental treatment for his son Harry, who was diagnosed with the 'Oshtoran syndrome', a rare ailment that had previously claimed the life of his mother and Norman's wife, Emily Osborn. The symbiote is voiced by Tony Todd. The symbiote is first teased in the end-credits scene of Marvel's Spider-Man (2018), where it is revealed that Norman Osborn has been keeping his son Harry in a state of suspension following the revelation that he was falling terminally ill to the 'Oshtoran syndrome', a degenerative disease that was passed through hereditary genes from his mother Emily Osborn, who had succumbed to the disease prior to the game's events. As a last resort, Norman imbued Harry with the symbiote as a temporary cure, but promised his son he wouldn't rest until he had found a way to eliminate the disease completely and restore his health. The end-credits scene of Marvel's Spider-Man: Miles Morales (2020) indirectly continues the events of the previous scenario, now showing Harry waking up from his period of