to the same side. Because they elevate the upper ribs, they also act as accessory muscles of respiration, along with the sternocleidomastoids. Relations The scalene muscles have an important relationship to other structures in the neck. The brachial plexus and subclavian artery pass between the anterior and middle scalenes. The subclavian vein and phrenic nerve pass anteriorly to the anterior scalene as the muscle crosses over the first rib. The phrenic nerve is oriented vertically as it passes in front of the anterior scalene, while the subclavian vein is oriented horizontally as it passes in front of the anterior scalene muscle. The passing of the brachial plexus and the subclavian artery through the space of the anterior and middle scalene muscles constitute the scalene hiatus (the term "scalene fissure" is also used). The region in which this lies is referred to as the scaleotracheal fossa. It is bounded by the clavicle inferior anteriorly, the trachea medially, posteriorly by the trapezius, and anteriorly by the platysma muscle. Clinical significance The anterior and middle scalene muscles can be involved in certain forms of thoracic outlet syndrome as well as myofascial pain syndrome, the symptoms of which may mimic a spinal disc herniation of the cervical vertebrae. Since the nerves of the brachial plexus pass through the space between the anterior and middle scalene muscles, that area is sometimes targeted with the administration of regional anesthesia by an anesthesia provider. The nerve block, called an interscalene block, may be performed prior to arm or shoulder surgery. According to the medical codes in the 2016 Procedural Coding Expert, published by the American Academy of Professional Coders, for Current Procedural Terminology (CPT) and other medical codes, the scalenus anticus muscle can be divided by reparative or reconstructive surgery, with (# 21705) or without (# 21700) resection of the cervical rib. History The scalenes used to be known as the lateral vertebral muscles. Etymology The muscles are named from Greek σκαληνός, or skalenos, meaning uneven as the pairs are all of differing length Additional images References Human anatomy Muscles of the head and neck