Löffler's syndrome is a disease in which eosinophils accumulate in the lung in response to a parasitic infection. The parasite can be Ascaris, Strongyloides stercoralis, or Dirofilaria immitis which can enter the body through contact with the soil. The symptoms of Löffler's syndrome include those of a parasitic infection such as abdominal pain and cramping, skin rashes and fatigue. Löffler's syndrome itself will cause difficulty breathing, wheeze, coughing as well as a fever. Diagnosis The diagnosis of Loffler's syndrome can be challenging, as the diagnostic criteria can be vague and consistent with a multitude of diseases or conditions. The disease's developmental trajectory is mostly unknown. Upon examination of symptoms, a doctor will likely request a chest x-ray looking for migratory pulmonary infiltrate, and blood testing, to confirm a diagnosis. Symptoms tend to be brief, but can range from mild to severe and include: fever, vomiting, increased respirations or difficulty breathing, cough, wheeze, and rash. Symptoms typically follow an exposure to allergens or certain drugs, and last approximately two weeks. Eosinophilia is the main feature of diagnostic criteria for Loffler's syndrome. Eosinophils are white blood cells that fight infection by destroying foreign substances in the body. This increase is determined through a blood test called a complete blood count, or CBC. A result of over 500 cells/mcL (cells per microliter of blood) is considered elevated. The normal range for eosinophils is less than 350 cells/mcL. Prevention While the outcomes of this syndrome have never led to death, the symptoms can last anywhere from 2 to 4 weeks after the parasite enters the body. Prevention of this syndrome is education-based, consisting of educating individuals on proper handwashing techniques, as well as how to correctly dispose of feces. Epidemiology This syndrome can be found anywhere. However, it is abnormally prevalent in tropical areas, showing higher prevalence in men than women. This syndrome is also exceedingly common in the warm damp parts of the world. The syndrome is also more likely to be contracted by small children since they spend an increased amount of time outside in the dirt. While it is still a mystery why the prevalence is higher in Indians, the warm damp environment is a perfect place for the parasites to grow and thrive. The epidemiological aspect of Löffler's syndrome isn't well known since there have been minimal statistics reported on the topic. History In 1909 a man named H. French