The dental follicle, also known as dental sac, is made up of mesenchymal cells and fibres surrounding the enamel organ and dental papilla of a developing tooth. It is a vascular fibrous sac containing the developing tooth and its odontogenic organ. The dental follicle (DF) differentiates into the periodontal ligament. In addition, it may be the precursor of other cells of the periodontium, including osteoblasts, cementoblasts and fibroblasts. They develop into the alveolar bone, the cementum with Sharpey's fibers and the periodontal ligament fibers respectively. Similar to dental papilla, the dental follicle provides nutrition to the enamel organ and dental papilla and also have an extremely rich blood supply. Role in tooth eruption The formative role of the dental follicle starts when the crown of the tooth is fully developed and just before tooth eruption into the oral cavity. Although tooth eruption mechanisms have yet to be understood entirely, generally it can be agreed that many factors, together, affect the tooth eruption process which is why it is very difficult to differentiate the causes and effects. There have been many theories proposed for tooth eruption. Ideas such as remodelling of the alveolar bone, root elongation and to a certain extent, the most probable reasoning for tooth eruption in human beings is the formation of the periodontal ligament. Bone remodelling Bone remodelling of the jaws has been associated to tooth eruption such that in the pre-eruptive phase of a tooth, the natural pattern of growth of the maxilla or mandible would theoretically move teeth by the selective deposition and reabsorption of bone in the adjacent surroundings of the tooth. A sequence of experiments in dogs does provide the most reliable substantiation to prove that bone remodelling is a cause of tooth movement. When an eruption is stopped by wiring the tooth germ on to the lower margin of the mandible or when the dental follicle remains undisturbed as the developing pre-molar is removed, osteoclasts enlarge the gubernacular canal while an eruptive pathway develops within the bone covering over the enucleated tooth. However, no eruptive pathway will develop if the dental follicle is removed. Furthermore, the replica will erupt with the development of an eruptive pathway as long as the dental follicle is preserved when an exact silicone or metal duplicate replaces the tooth germ. Such observations should be examined judiciously and in great detail. Firstly, eruptive pathways have unmistakably been demonstrated