Sabina Nikolayevna Spielrein (; 7 November 25 October 1885 OS – 11 August 1942) was a Russian physician and one of the first female psychoanalysts. She was in succession the patient, then student, then colleague of Carl Gustav Jung, with whom she had an intimate relationship during 1908–1910, as is documented in their correspondence from the time and her diaries. She also met, corresponded, and had a collegial relationship with Sigmund Freud. She worked with and psychoanalysed Swiss developmental psychologist Jean Piaget. She worked as a psychiatrist, psychoanalyst, teacher and paediatrician in Switzerland and Russia. In a thirty-year professional career, she published over 35 papers in three languages (German, French and Russian), covering psychoanalysis, developmental psychology, psycholinguistics and educational psychology. Among her works in the field of psychoanalysis is the essay titled "Destruction as the Cause of Coming Into Being", written in German in 1912. Spielrein was a pioneer of psychoanalysis and one of the first to introduce the concept of the death instinct. She was one of the first psychoanalysts to conduct a case study on schizophrenia and have a dissertation appear in a psychoanalytic journal. Spielrein is increasingly recognized as an important and innovative thinker who was marginalized in history because of her unusual eclecticism, refusal to join factions, feminist approach to psychology, and her murder in the Holocaust. Biography Family and early life 1885–1904 She was born in 1885 into a wealthy Jewish family in Rostov-on-Don, Russian Empire. Her mother Eva (born Khave) Lublinskaya was the daughter and granddaughter of rabbis from Yekaterinoslav. Eva trained as a dentist, but did not practice. Sabina's father Nikolai (born Naftul) Spielrein was an agronomist. After moving from Warsaw to Rostov, he became a successful merchant. On her birth certificate, Sabina appeared as Sheyve Naftulovna, but throughout her life and on official documents she used the name Sabina Nikolayevna. She was the eldest of five children. All three of her brothers later became eminent scientists. One of them, Isaac Spielrein, was a Soviet psychologist, a pioneer of work psychology. Another was the mathematician Jan Spielrein. From her early childhood, Sabina was highly imaginative and believed that she had a 'higher calling' to achieve greatness, and she communicated about this privately with a 'guardian spirit'. However, her parents' marriage was turbulent and she experienced physical violence from both of them. She suffered from multiple somatic symptoms and obsessions. Some commentators believe she