Route 143 is a short state highway in southern Missouri. The route starts at Missouri Route 34 near Patterson, and it travels north through Sam A. Baker State Park. North of the park, Route 143 turns westwards and ends at Route 49 at Des Arc. The road that became part of Route 143 was constructed around 1934, as a supplemental route traveling east from Des Arc. Four years later, a new state route, Route 101, was constructed from Route 34 to the state park, and it was renumbered to Route 143 in 1941. By 1964, a new supplemental route connected the two routes. The two supplemental routes were merged into Route 143 around six years later. Route description Route 143 is located in northern Wayne and southern Iron counties. In 2016, the Missouri Department of Transportation (MoDOT) calculated 672 vehicles, including 46 trucks, traveling on the route north of Route 34. The route starts at Route 34 east of Patterson, and it crosses Clark Creek at County Road 312 (CRD 312) as it travels north. Past Logan Creek, Route 143 turns northeastwards towards Sam A. Baker State Park. The road travels along Big Creek, intersecting entrances to the state park's campground and visitor center, and then it crosses the creek. Northeast of CRD 318, Route 143 turns northwestwards and westwards near CRD 319. The road crosses Crane Pond Creek west of CRD 321. The route enters Iron County past Brunot. Inside the county, Route 143 continues traveling through a forested rural area. The road briefly turns south between CRD 162 and CRD 163, before turning west and paralleling Big Creek. Route 143 crosses the creek again near CRD 160 and enters Des Arc at CRD 167. The route ends at a T-intersection with Route 49 on the northern side of the village. History Around 1934, a gravel road that extended several miles eastwards from Route 49 in Des Arc was designated as Route N. By 1937, another gravel road from Route 34 to Sam A. Baker State Park was constructed and designated as Route 101. Route N was extended to the Iron–Wayne county line by 1940. The road was renumbered to Route 143 by 1941, and the Route 101 designation was reused for another highway in Ozark and Howell counties. In late May of that year, a project to pave the entirety of Route 143 in oil aggregate treatment was