Traditionally vice-prime ministers are in charge of an area of general state government policy such as the agro-industrial complex, humanitarian affairs, economic affairs, or regional policy. On certain occasions, those deputies may be given regular ministerial portfolios as well, as happened in the 2010 Azarov Government. Dismissal and resignation The prime minister, like other Cabinet members, may resign voluntarily by tendering their resignation to parliament (according to the Constitution of Ukraine, the prime minister can only be dismissed by parliamentary vote). Parliament must then consider the matter no later than the 10th day after the resignation application is received, if parliament was not in session at the time of resignation then no later than the first plenary week of the next regular session. A resignation by the prime minister results in the dismissal of the entire Cabinet. After the adoption of the current constitution in 1996, only prime ministers Pavlo Lazarenko and Mykola Azarov have left their post this way. Prime ministers do not have a set term limit, staying in office for the duration of the parliament term, resignation, or dismissal. Before the constitutional reform of 2004, the prime minister was usually dismissed unilaterally by the president. After the reform, the prime minister can only be dismissed by the parliament. Formally, the Verkhovna Rada needed to pass a resolution of no confidence of the cabinet, which had to result in the prime minister's resignation. However, the parliament could not put such a resolution to the vote within one year of the approval of the cabinet's official programme. The Cabinets of prime ministers Viktor Yushchenko and Viktor Yanukovych were dismissed in this way, with the latter refusing to tender his resignation to the president claiming a violation of the one-year period condition. The Cabinet of Yuriy Yekhanurov had also been formally dismissed, but the parliamentary act was subsequently repealed. List of prime ministers (1991–present) Since Ukrainian independence from the Soviet Union in 1991, there have been 15 prime ministers (19 including acting PMs). Yulia Tymoshenko was the first (and only) female prime minister of Ukraine. Before the re-appointment as Prime Minister of Mykola Azarov, Tymoshenko was the longest serving prime minister serving for two terms and a total of 1,029 days (days serving as acting prime minister are not included in these numbers). Since Azarov was re-appointed as prime minister on 13 December 2012, he has since broken Tymoshenko's record.