National Road 38 (, abbreviated as EO38) is a single carriageway road in western and central Greece. It connects Thermo with Lamia, via Agrinio and Karpenisi. It passes through the regional units Aetolia-Acarnania, Evrytania and Phthiotis. The section between Agrinio and Lamia coincides with the European route E952. Route The western end of the National Road is in the small town Thermo, in Aetolia-Acarnania. It first runs west along the northern shore of Lake Trichonida. It turns north at Agrinio, and continues through the sparsely populated mountains of northeastern Aetolia-Acarnania. The highway crosses the Kremasta reservoir by the Episkopi bridge. It continues east through the mountainous Agrafa area, part of the Pindus mountains. It passes through Karpenisi, the capital town of Evrytania. East of Karpenisi, it passes through a tunnel under the Tymfristos mountain and enters the Spercheios valley. It follows the river Spercheios downstream, through Makrakomi and Leianokladi, and ends in Lamia. The National Road 38 passes through the following places: Thermo Paravola Agrinio Agios Vlasios Episkopi Fragkista Kalesmeno Karpenisi Tymfristos Agios Georgios Tymfristou Makrakomi Leianokladi Lamia 38 Roads in Western Greece Roads in Central Greece