where he remained active at the bench until recently. In 1993, Jeffrey I. Seeman published Life during a Golden Age of Peptide Chemistry, Merrifield's autobiography, in the series "Profiles, Pathways, and Dreams" for the American Chemical Society. He received the Association of Biomolecular Resource Facilities Award for outstanding contributions to Biomolecular Technologies in 1998. The achievement of synthesizing ribonuclease A (with Bernd Gutte) was all the more significant in that it demonstrated that the linear sequence of amino acids joined in peptide bonds determined directly the tertiary structure of a peptide or protein. I.e. that information coded in one dimension can directly determine the three-dimensional structure of a molecule. SPPS has been expanded to include solid phase synthesis of nucleotides and saccharides. Personal life After raising their 6 children, James, Nancy, Betsy, Cathy, Laurie and Sally, his wife Elizabeth (Libby), a biologist by training, joined the Merrifield laboratory at Rockefeller University where she worked for over 23 years. After a long illness R. Bruce Merrifield died on May 14, 2006, at the age of 84 in his home in Cresskill, New Jersey. At the time of his death he was survived by his wife Libby, their 6 children and 16 grandchildren. Libby died on September 13, 2017. References External links Ulf Ragnarsson, "Bruce Merrifield", Biographical Memoirs of the National Academy of Sciences (2013) American biochemists American Nobel laureates Members of the United States National Academy of Sciences Nobel laureates in Chemistry University of California, Los Angeles faculty University of California, Los Angeles alumni People from Cresskill, New Jersey People from Fort Worth, Texas 1921 births 2006 deaths Recipients of the Albert Lasker Award for Basic Medical Research Rockefeller University people