| 75 | April 8 | L.A. Lakers | L 94–117 | Ray Allen (30) | Collison, Evans (11) | Flip Murray (7) | KeyArena17,072 | 50–25 |- style="background:#fbb;" | 76 | April 9 | @ Denver | L 105–121 | Ray Allen (32) | Reggie Evans (10) | Luke Ridnour (7) | Pepsi Center19,751 | 50–26 |- style="background:#fbb;" | 77 | April 11 | Houston | L 78–90 | Ray Allen (18) | Nick Collison (8) | Murray, Wilkins (4) | KeyArena17,072 | 50–27 |- style="background:#fbb;" | 78 | April 13 | Dallas | L 90–95 | Ray Allen (19) | Reggie Evans (13) | Daniels, Ridnour (4) | KeyArena16,502 | 50–28 |- style="background:#bfb;" | 79 | April 15 | New Orleans | W 97–72 | Ray Allen (32) | Nick Collison (10) | Ray Allen (7) | KeyArena17,072 | 51–28 |- style="background:#bfb;" | 80 | April 17 | @ Minnesota | W 109–94 | Ray Allen (34) | Ray Allen (10) | Luke Ridnour (11) | Target Center17,779 | 52–28 |- style="background:#fbb;" | 81 | April 19 | @ Dallas | L 96–101 | Allen, Lewis (21) | Collison, Evans (9) | Luke Ridnour (8) | American Airlines Center20,534 | 52–29 |- style="background:#fbb;" | 82 | April 20 | @ Houston | L 78–106 | Flip Murray (22) | Nick Collison (9) | Luke Ridnour (8) | Toyota Center18,194 | 52–30 Playoffs |- align="center" bgcolor="#ccffcc" | 1 | April 23 | Sacramento | W 87–82 | Ray Allen (28) | Evans, James (15) | Daniels, Ridnour (4) | KeyArena17,072 | 1–0 |- align="center" bgcolor="#ccffcc" | 2 | April 26 | Sacramento | W 105–93 | Ray Allen (26) | Jerome James (9) | Allen, Ridnour (6) | KeyArena17,072 | 2–0 |- align="center" bgcolor="#ffcccc" | 3 | April 29 | @ Sacramento | L 104–116 | Ray Allen (33) | Jerome James (9) | Allen, Ridnour (5) | ARCO Arena17,317 | 2–1 |- align="center" bgcolor="#ccffcc" | 4 | May 1 | @ Sacramento | W 115–102 | Ray Allen (45) | James, Lewis (8) | Allen, Daniels (6) | ARCO Arena17,317 | 3–1 |- align="center" bgcolor="#ccffcc" | 5 | May 3 | Sacramento | W 122–118 | Ray Allen (30) | Nick Collison (9) | Antonio Daniels (8) | KeyArena17,072 | 4–1 |- |- align="center" bgcolor="#ffcccc" | 1 | May 8 | @ San Antonio | L 81–103 |