South Carolina Highway 28 Business may refer to: South Carolina Highway 28 Business (Abbeville), a former business loop in Abbeville South Carolina Highway 28 Business (Anderson), a business loop in Anderson South Carolina Highway 28 Business (Clemson), a former business loop in Clemson South Carolina Highway 28 Business (Pendleton), a business loop in Pendleton South Carolina Highway 28 Business (Seneca), a former business loop in Seneca 028 Business 028 Business