44,061 || 84–67 || L1 |- style="background:#cfc;" | 152 || September 18 || Nationals || 5–1 || Wainwright (13–9) || Scherzer (10–7) || Martínez (21) || 37,669 || 85–67 || W1 |- style="background:#cfc;" | 153 || September 19 || @Cubs || 5–4 (10) || Miller (5–5) || Kimbrel (0–3) || Gallegos (1) || 39,524 || 86–67 || W2 |- style="background:#cfc;" | 154 || September 20 || @Cubs || 2–1 || Helsley (2–0) || Phelps (2–1) || Martínez (22) || 39,106 || 87–67 || W3 |- style="background:#cfc;" | 155 || September 21 || @Cubs || 9–8 || Gant (11–1) || Kimbrel (0–4) || Martínez (23) || 40,071 || 88–67 || W4 |- style="background:#cfc;" | 156 || September 22 || @Cubs || 3–2 || Webb (2–1) || Darvish (6–8) || Miller (6) || 38,606 || 89–67 || W5 |- style="background:#cfc;" | 157 || September 23 || @Diamondbacks || 9–7 || Wainwright (14–9) || Young (7–5) || Martínez (24) || 24,826 || 90–67 || W6 |- style="background:#fbb;" | 158 || September 24 || @Diamondbacks || 2–3 (19) || Ginkel (3–0) || Brebbia (3–4) || — || 26,097 || 90–68 || L1 |- style="background:#fbb;" | 159 || September 25 || @Diamondbacks || 7–9 || Kelly (13–14) || Fernández (0–1) || Bradley (17) || 21,420 || 90–69 || L2 |- style="background:#fbb;" | 160 || September 27 || Cubs || 2–8 || Wieck (2–2) || Miller (5–6) || — || 46,530 || 90–70 || L3 |- style="background:#fbb;" | 161 || September 28 || Cubs || 6–8 || Cishek (4–6) || Wainwright (14–10) || Kintzler (1) || 46,971 || 90–71 || L4 |- style="background:#cfc;" | 162 || September 29 || Cubs || 9–0 || Flaherty (11–8) || Holland (2–5) || — || 47,200 || 91–71 || W1 |- |- | Legend: = Win = Loss = PostponementBold = Cardinals team member Postseason |- style="background:#bfb;" | 1 || October 3 || @ Braves || 7–6 || Martínez (1–0) || Melancon (0–1) || — || 42,631 || 1–0 |- style="background:#fbb;" | 2 || October 4 || @ Braves || 0–3 || Foltynewicz (1–0) || Flaherty (0–1) || Melancon (1) || 42,911 || 1–1 |- style="background:#fbb;" | 3 || October 6 || Braves || 1–3 || Newcomb (1–0) || Martínez (1–1) || Melancon (2) || 46,701 || 1–2 |- style="background:#bfb;" | 4 || October 7 || Braves || 5–4 || Mikolas (1–0) || Teherán (0–1) || — || 42,203 ||