|135||August 30||@ Rockies || 9–4 || Agrazal (4–3) || Senzatela (8–9) || — || 27,789 || 58–77 || W2 |-style="background:#bfb |136||August 31||@ Rockies || 11–4 || Musgrove (9–12) || Melville (1–1) || — || 37,293 || 59–77 || W3 |- |-style="background:#bfb |137||September 1||@ Rockies || 6–2 || Brault (4–3) || Hoffman (1–5) || — || 32,685 || 60–77 || W4 |-style="background:#fbb |138||September 3||Marlins || 4–5 || Conley (2–7) || Markel (0–1) || Ureña (1) || 9,169 || 60–78 || L1 |-style="background:#bfb |139||September 4||Marlins || 6–5 || Wang (2–0) || Ureña (4–8) || — || 9,043 || 61–78 || W1 |-style="background:#fbb |140||September 5||Marlins || 7–10 || Moran (1–0) || Agrazal (4–4) || — || 9,642 || 61–79 || L1 |-style="background:#bfb |141||September 6||Cardinals || 9–4 || Wang (3–0) || Miller (4–5) || Vázquez (25) || 19,090 || 62–79 || W1 |-style="background:#fbb |142||September 7||Cardinals || 1–10 || Wainwright (11–9) || Brault (4–4) || — || 23,996 || 62–80 || L1 |-style="background:#fbb |143||September 8||Cardinals || 0–2 || Flaherty (10–7) || Marvel (0–1) || Martínez (19) || 18,363 || 62–81 || L2 |-style="background:#bfb |144||September 9||@ Giants || 6–4 || Rodríguez (4–5) || Abad (0–2) || Vázquez (26) || 26,826 || 63–81 || W1 |-style="background:#fbb |145||September 10||@ Giants || 4–5 || Cueto (1–0) || Keller (1–4) || Anderson (1) || 26,877 || 63–82 || L1 |-style="background:#bfb |146||September 11||@ Giants || 6–3 || Feliz (3–4) || Webb (1–2) || Vázquez (27) || 26,627 || 64–82 || W1 |-style="background:#bfb |147||September 12||@ Giants || 4–2 || Musgrove (10–12) || Samardzija (10–12) || Vázquez (28) || 30,918 || 65–82 || W2 |-style="background:#fbb |148||September 13||@ Cubs || 8–17 || Lester (13–10) || Brault (4–5) || Mills (1) || 39,080 || 65–83 || L1 |-style="background:#fbb |149||September 14||@ Cubs || 1–14 || Hendricks (11–9) || Marvel (0–2) || — || 39,928 || 65–84 || L2 |-style="background:#fbb |150||September 15||@ Cubs || 6–16 || Wieck (1–1)|| Williams (7–7) || — || 39,103 || 65–85 || L3 |-style="background:#fbb |151||September 17||Mariners || 0–6 || Gonzales (16–11) || Keller (1–5) || — || 10,933 || 65–86 || L4 |-style="background:#fbb |152||September 18||Mariners || 1–4 || Milone (4–9) || Agrazal (4–5) || Magill (5) || 9,875 || 65–87 || L5 |-style="background:#fbb |153||September 19||Mariners || 5–6 || Brennan (3–6) || Holmes (1–2) || Swanson (1) || 12,543 || 65–88 || L6 |-style="background:#fbb |154||September 20||@ Brewers || 1–10 || Anderson (7–4) || Brault (4–6) || — || 43,390 || 65–89 || L7