(3–1) | — | 25,364 | 22–36 | W3 |-style="background:#bfb;" | 59 | June 5 | @ Brewers | 8–3 | Alcántara (3–5) | Nelson (0–1) | — | 26,615 | 23–36 | W4 |-style="background:#fbb;" | 60 | June 6 | @ Brewers | 1–5 | Peralta (3–2) | Smith (3–4) | Hader (14) | 25,409 | 23–37 | L1 |-style="background:#fbb;" | 61 | June 7 | Braves | 1–7 | Soroka (7–1) | Ureña (4–7) | — | 8,589 | 23–38 | L2 |-style="background:#fbb;" | 62 | June 8 | Braves | 0–1 | Teherán (4–4) | Richards (3–6) | Jackson (9) | 9,771 | 23–39 | L3 |-style="background:#fbb;" | 63 | June 9 | Braves | 6–7 (12) | Winkler (3–1) | Conley (1–6) | Tomlin (1) | 10,959 | 23–40 | L4 |-style="background:#fbb;" | 64 | June 10 | Cardinals | 1–4 | Wacha (4–2) | Alcántara (3–6) | Hicks (13) | 6,585 | 23–41 | L5 |-style="background:#fbb;" | 65 | June 11 | Cardinals | 1–7 | Hudson (5–3) | Hernández (0–1) | — | 6,308 | 23–42 | L6 |-style="background:#bfb;" | 66 | June 12 | Cardinals | 9–0 | Yamamoto (1–0) | Mikolas (4–7) | — | 7,001 | 24–42 | W1 |-style="background:#fbb;" | 67 | June 14 | Pirates | 0–11 | Brault (3–1) | Richards (3–7) | — | 8,340 | 24–43 | L1 |-style="background:#bfb;" | 68 | June 15 | Pirates | 4–3 | López (5–5) | Hartlieb (0–1) | Romo (12) | 11,464 | 25–43 | W1 |-style="background:#fbb;" | 69 | June 16 | Pirates | 4–5 | Rodríguez (1–3) | Anderson (2–3) | Vázquez (16) | 12,472 | 25–44 | L1 |-style="background:#fbb; | 70 | June 17 | @ Cardinals | 0–5 | Mikolas (5–7) | Hernández (0–2) | — | 41,274 | 25–45 | L2 |-style="background:#bfb;" | 71 | June 18 | @ Cardinals | 6–0 | Yamamoto (2–0) | Flaherty (4–4) | — | 41,467 | 26–45 | W1 |-style="background:#fbb;" | 72 | June 19 | @ Cardinals | 1–2 | Gant (7–0) | Conley (1–7) | — | 40,126 | 26–46 | L1 |-style="background:#bfb;" | 73 | June 20 | @ Cardinals | 7–6 | García (1–0) | Miller (3–3) | Romo (13) | 42,446 | 27–46 | W1 |-style="background:#bfb;" | 74 | June 21 | @ Phillies | 2–1 | Alcántara (4–6) | Nola (6–2)