— || 27,882 || 54–61 || W2 |-style=background:#bfb ||116|| August 10 || Rockies || 8–5 || Muñoz (1–1) || Díaz (4–3) || Yates (33) || 42,564 || 55–61 || W3 |-style=background:#fbb ||117|| August 11 || Rockies || 3–8 || Márquez (11–5) || Stammen (6–6) || — || 28,930 || 55–62 || L1 |-style=background:#fbb ||118|| August 12 || Rays || 4–10 || Pruitt (2–0) || Lucchesi (7–7) || — || 21,301 || 55–63 || L2 |-style=background:#fbb ||119|| August 13 || Rays || 5–7 || Anderson (4–4) || Báez (0–1) || Pagán (13) || 25,261 || 55–64 || L3 |-style=background:#bfb ||120|| August 14 || Rays || 7–2 || Quantrill (6–6) || Beeks (5–2) || — || 22,886 || 56–64 || W1 |-style=background:#fbb ||121|| August 16 || @ Phillies || 4–8 || Velasquez (5–7) || Paddack (7–6) || — || 26,084 || 56–65 || L1 |-style=background:#bfb ||122|| August 17 || @ Phillies || 5–3 || Lamet (2–2) || Pivetta (4–5) || Yates (34) || 31,332 || 57–65 || W1 |-style=background:#bfb ||123|| August 18 || @ Phillies || 3–2 || Lucchesi (8–7) || Hughes (2–5) || Yates (35) || 36,210 || 58–65 || W2 |-style=background:#bfb ||124|| August 19 || @ Reds || 3–2 || Perdomo (2–3) || Bauer (10–10) || Yates (36) || 10,176 || 59–65 || W3 |-style=background:#fbb ||125|| August 20 || @ Reds || 2–3 || Gray (9–6) || Quantrill (6–4) || Iglesias (25) || 12,468 || 59–66 || L1 |-style=background:#fbb ||126|| August 21 || @ Reds || 2–4 || Castillo (12–5) || Yardley (0–1) || Iglesias (26) || 13,397 || 59–67 || L2 |-style=background:#fbb ||127|| August 23 || Red Sox || 0–11 || Rodríguez (15–5) || Paddack (7–7) || — || 42,904 || 59–68 || L3 |-style=background:#fbb ||128|| August 24 || Red Sox || 4–5 || Barnes (4–4) || Yates (0–4) || Workman (8) || 42,625 || 59–69 || L4 |-style=background:#bfb ||129|| August 25 || Red Sox || 3–1 || Lucchesi (9–7) || Johnson (1–3) || Yates (37) || 38,026 || 60–69 || W1 |-style=background:#bfb ||130|| August 26 || Dodgers || 4–3 || Lauer (7–8) || May (1–3) || Yates (38) || 26,172 || 61–69 || W2 |-style=background:#fbb ||131|| August 27 || Dodgers || 0–9 || Buehler (11–3) || Quantrill (6–5) || — || 27,952 || 61–70 || L1 |-style=background:#fbb ||132|| August 28 || Dodgers || 4–6 || Jansen (4–3) || Yates (0–5) || Sadler (1) || 26,871 || 61–71 ||