the prospect of a sequel, Ojala remarked in an interview with HorrorNews.net, "we want to see how the film does and we leave it open-ended where there could absolutely be a sequel". Critical reception Strange Nature received mixed reviews from critics. It holds an approval rating of on the aggregate review site Rotten Tomatoes, based on reviews, with an average rating of . Freddy Beans of Ain't It Cool News called it an "awesome little horror gem" and a "brilliant freshman effort" for director Ojala, commending the "fantastic" cinematography and creature effects and concluding "I can't explain how much I really enjoyed my time watching this unique experience". Horror magazine Rue Morgue delivered most of its praise onto the film's ensemble cast, namely its "three-dimensional characterizations" and Lisa Sheridan's performance, describing the overall film as "[weaving] threads of Erin Brockovich, It's Alive, and Cabin Fever into a quirky, nasty, sometimes inspiring tapestry of unlikely-hero-vs.-enviro-terror". The Los Angeles Times was slightly more ambivalent, feeling the film lacked scares but nevertheless praised the "top-notch" creature effects and "likeable characters", complimenting the small town "slice of life" angle and giving Ojala "kudos" for "making his setting essential to his story". FanSideds Hidden Remote, titling their review with "science-fiction meets real science in perfect blend", appreciated the film's environmental messages, acknowledging Ojala for "[presenting] all these issues in an entertaining fashion" as well as noting the "phenomenal" chemistry between the ensemble cast. Horror Fuel awarded Strange Nature a perfect rating of 5 stars, applauding the depth and relatability of the characters, writing "everything just congeals into a highly effective, borderline realistic, terror tale that is as disturbing (and trust me it gets very disturbing) as it is engaging". 28 Days Later Analysis lauded the "compelling" and "well-drawn" characters, "excellent" make-up effects and the film's use of dark humor, stating "Strange Nature offers a lot in its short, but bloody runtime" and "indie horror fans should see this production". Bobby LePire of Film Threat gave the film a negative review, stating "The directing style of Strange Nature fails to bring any atmosphere, the acting is so nondescript that it barely registers (with two notable exceptions), and a lack of cohesive vision leaves the movie uncertain of what it truly is. An absolute waste of time for all involved, especially the audience." Although he panned most performances, including Sheridan's, whom he called "an entirely blank slate",