7–5 || L1 |-style=background:#bfb;" ||13|| April 10 || @ Giants || 3–1 || Margevicius (1–1) || Rodríguez (1–2) || Yates (7) || 28,584 || 8–5 || W1 |-style=background:#bfb;" ||14|| April 11 || @ Diamondbacks || 7–6 || Stammen (1–0) || Bradley (0–1) || Wingenter (1) || 15,449 || 9–5 || W2 |-style=background:#bfb;" ||15|| April 12 || @ Diamondbacks || 2–1 || Reyes (1–0) || Weaver (0–1) || Yates (8) || 22,209 || 10–5 || W3 |-style=background:#bfb;" ||16|| April 13 || @ Diamondbacks || 5–4 || Stammen (2–0) || Andriese (2–1) || Yates (9) || 27,256 || 11–5 || W4 |-style=background:#fbb;" ||17|| April 14 || @ Diamondbacks || 4–8 || Greinke (2–1) || Lauer (2–2) || — || 25,489 || 11–6 || L1 |-style=background:#fbb;" ||18|| April 15 || Rockies || 2–5 || Senzatela (1–0) || Lucchesi (2–2) || Davis (1) || 24,867 || 11–7 || L2 |-style=background:#fbb;" ||19|| April 16 || Rockies || 2–8 || Gray (1–3) || Margevicius (1–2) || — || 24,963 || 11–8 || L3 |-style=background:#fbb;" ||20|| April 18 || Reds || 1–4 || Roark (1–0) || Paddack (0–1) || Iglesias (3) || 26,577 || 11–9 || L4 |-style=background:#fbb;" ||21|| April 19 || Reds || 2–3 || Hughes (2–0) || Stammen (2–1) || Lorenzen (1) || 33,442 || 11–10 || L5 |-style=background:#fbb;" ||22|| April 20 || Reds || 2–4 || Castillo (2–1) || Lauer (2–3) || Iglesias (4) || 37,137 || 11–11 || L6 |-style=background:#bfb;" ||23|| April 21 || Reds || 4–3 || Lucchesi (3–2) || Mahle (0–2) || Yates (10) || 25,932 || 12–11 || W1 |-style=background:#bfb;" ||24|| April 23 || Mariners || 6–3 || Margevicius (2–2) || Swanson (0–2) || Yates (11) || 25,154 || 13–11 || W2 |-style=background:#bfb;" ||25|| April 24 || Mariners || 1–0 || Paddack (1–1) || Hernández (1–2) || Yates (12) || 23,417 || 14–11 || W3 |-style=background:#bfb;" ||26|| April 26 || @ Nationals || 4–3 || Stammen (3–1) || Doolittle (3–1) || Yates (13) || 27,193 || 15–11 || W4 |-style=background:#bfb;" ||27|| April 27 || @ Nationals || 8–3 || Perdomo (1–0) || Suero (1–3) || — || 35,422 || 16–11 || W5 |-style=background:#fbb;" ||28|| April 28 || @ Nationals || 6–7 || Miller (1–0) || Wisler (1–1) || — || 30,186 || 16–12|| L1 |-style=background:#fbb;" ||29|| April 29 || @ Braves || 1–3 || Soroka (2–1) || Margevicius (2–3) || Webb (1) || 19,353 || 16–13 || L2 |-style=background:#bfb;" ||30||