June 9 || @ Indians || 7–6 || Chapman (1–1) || Pérez (1–1) || Tarpley (1) || Progressive Field || 29,028 || 40–24 |-style=background:#bbb | — || June 10 || Mets || colspan=7 | Postponed (inclement weather: rain). Makeup date: June 11 (doubleheader) |-style=background:#bfb | 65 || June 11 || Mets || 12–5 || Tanaka (4–5) || Wheeler (5–4) || — || Yankee Stadium || 41,538 || 41–24 |-style=background:#fbb | 66 || June 11 || Mets || 4–10 || Vargas (3–3) || Paxton (3–3) || — || Yankee Stadium || 44,698 || 41–25 |-style=background:#fbb | 67 || June 13 || @ White Sox || 4–5 || Marshall (2–0) || Ottavino (2–2) || Bummer (1) || Guaranteed Rate Field || 25,311 || 41–26 |-style=background:#fbb | 68 || June 14 || @ White Sox || 2–10 || Giolito (10–1) || Sabathia (3–4) || — || Guaranteed Rate Field || 31,438 || 41–27 |-style=background:#bfb | 69 || June 15 || @ White Sox || 8–4 || Cortes Jr. (1–0) || López (4–7) || — || Guaranteed Rate Field || 36,074 || 42–27 |-style=background:#bfb | 70 || June 16 || @ White Sox || 10–3 || Paxton (4–3) || Despaigne (0–2) || — || Guaranteed Rate Field || 37,277 || 43–27 |-style=background:#bfb | 71 || June 17 || Rays || 3–0 || Tanaka (5–5) || Chirinos (7–3) || — || Yankee Stadium || 39,042 || 44–27 |-style=background:#bfb | 72 || June 18 || Rays || 6–3 || Happ (7–3) || Roe (0–3) || Chapman (19) || Yankee Stadium || 40,479 || 45–27 |-style=background:#bfb | 73 || June 19 || Rays || 12–1 || Sabathia (4–4) || Snell (4–6) || — || Yankee Stadium || 41,144 || 46–27 |-style=background:#bfb | 74 || June 20 || Astros || 10–6 || Cortes Jr. (2–0) || Valdez (3–3) || Chapman (20) || Yankee Stadium || 41,030 || 47–27 |-style=background:#bfb | 75 || June 21 || Astros || 4–1 || Paxton (5–3) || Peacock (6–5) || Chapman (21) || Yankee Stadium || 41,166 || 48–27 |-style=background:#bfb | 76 || June 22 || Astros || 7–5 || Holder (5–2) || Pressly (1–1) || Britton (3) || Yankee Stadium || 46,034 || 49–27 |-style=background:#fbb | 77 || June 23 || Astros || 4–9 || Verlander (10–3) || Happ (7–4) || — || Yankee Stadium || 46,769 || 49–28 |-style=background:#bfb | 78 || June 24 || Blue Jays || 10–8 || Sabathia