9,043 | 49–89 | L1 |-style="background:#bfb;" | 139 | September 5 | @ Pirates | 10–7 | Moran (1–0) | Agrazal (4–4) | — | 9,642 | 50–89 | W1 |-style="background:#fbb;" | 140 | September 6 | Royals | 0–3 | López (3–7) | López (5–8) | Kennedy (27) | 8,915 | 50–90 | L1 |-style="background:#fbb | 141 | September 7 | Royals | 2–7 | Duffy (6–6) | Conley (2–8) | Hill (1) | 13,112 | 50–91 | L2 |-style="background:#bfb;" | 142 | September 8 | Royals | 9–0 | Alcántara (5–12) | Montgomery (3–8) | — | 10,934 | 51–91 | W1 |-style="background:#fbb;" | 143 | September 9 | Brewers | 3–8 | Albers (6–5) | Dugger (0–2) | — | 6,672 | 51–92 | L1 |-style="background:#fbb;" | 144 | September 10 | Brewers | 3–4 | Guerra (9–5) | Conley (2–9) | Pomeranz (1) | 7,215 | 51–93 | L2 |-style="background:#fbb;" | 145 | September 11 | Brewers | 5–7 | Suter (2–0) | Ureña (4–9) | Hader (30) | 7,815 | 51–94 | L3 |-style="background:#fbb;" | 146 | September 12 | Brewers | 2–3 | Peralta (6–3) | Smith (8–10) | Hader (31) | 7,375 | 51–95 | L4 |-style="background:#fbb;" | 147 | September 13 | @ Giants | 0–1 | Beede (5–9) | Alcántara (5–13) | Anderson (2) | 33,418 | 51–96 | L5 |-style="background:#bfb;" | 148 | September 14 | @ Giants | 4–2 | García (3–1) | Anderson (3–5) | Ureña (2) | 38,663 | 52–96 | W1 |-style="background:#fbb;" | 149 | September 15 | @ Giants | 1–2 | Rogers (2–0) | García (3–2) | Smith (33) | 39,663 | 52–97 | L1 |-style="background:#fbb;" | 150 | September 16 | @ Diamondbacks | 5–7 | Hirano (5–5) | Guerrero (1–2) | Ginkel (1) | 15,897 | 52–98 | L2 |-style="background:#bfb;" | 151 | September 17 | @ Diamondbacks | 12–6 | Smith (9–10) | Andriese (5–5) | — | 19,745 | 53–98 | W1 |-style="background:#fbb;" | 152 | September 18 | @ Diamondbacks | 4–5 | Leake (12–11) | Alcantara (5–14) | Bradley (15) | 17,731 | 53–99 | L1 |-style="background:#fbb;" | 153 | September 20 | Nationals | 4–6 | Sánchez (10–8) | Dugger (0–3) | Hudson (5) | 12,775 | 53–100 | L2 |-style="background:#fbb;" | 154 | September 21 | Nationals | 4–10 (10) | Suero (6–8) | Ureña (4–10)