Morphokinetics (‘morpho’’ form/shape and ‘kinetics’ movement) refers to time specific morphological changes during embryo development providing dynamic information on a fertilized egg. The detailed information eases morphological selection of embryos with high implantation potential to be used in In-Vitro Fertilisation treatment. Technology The traditional method for selection of embryos to be used for embryo transfer in fertility treatments such as IVF, involves assessing the morphology of a fertilized egg at crucial time points under a microscope. The incorporation of time lapse imaging tools in an incubator is a novel technology that allows images of embryo development to be captured frequently. This together with softwares allows embryologists and clinicians to interpret the embryo development information captured and select embryos for transfer in IVF treatment. Research for an algorithm to select a single embryo that would lead to the best clinical pregnancy outcome is underway. Time-Lapse incubators can be used for any patient, but they are especially indicated for: -Patients with previous cycles of implantation failure. -Patients with recurrent miscarriages. -Patients with many oocytes who wish to transfer a single embryo, since it improves their selection. Morphology Morphology of the embryo is studied in scientific research and often marked by stages. For further details of the processes that occur within each stage, see Human embryogenesis. 1. Fertilization After the egg is fertilized by the sperm, a zygote (single diploid cell) is formed. At this stage, it should have two pronuclei, one of each derived from the egg and the sperm cell respectively and two tiny cells called polar bodies. 2. Cleavage This begins when the zygote divides into two cells via mitosis. The division continues such that each cell divides into another two cells, which results in a multiplying effect. 3. Morula The ball of cells formed after the multiple divisions is called a morula. It consists of about 16-32 cells in a ball within a translucent, elastic layer called the zona pellucida. It will then undergo compaction which is a process where the cells bind firmly together and continue to develop into a blastocyst. 4. Blastocyst Blastulation is marked by the appearance of a fluid-filled cavity (blastocoel) surrounded by a single layer of cells called the trophectoderm and the inner cell mass. The fetus is developed from the inner cell mass while the placenta is derived from the trophectoderm. Benefits Morphokinetics has the potential advantage over standard morphological evaluation as it