|| June 17 || Indians || 7–2 || Lynn (8–4) || Clevinger (1–1) || — || 20,860 || 39–33 || W1 |- style="background:#fbb;" | 73 || June 18 || Indians || 3–10 || Plesac (2–2) || Sampson (5–4) || — || 19,233 || 39–34 || L1 |- style="background:#fbb;" | 74 || June 19 || Indians || 4–10 || Pérez (2–1) || Palumbo (0–1) || — || 22,906 || 39–35 || L2 |- style="background:#cfc;" | 75 || June 20 || Indians || 4–2 || Minor (7–4) || Bieber (6–3) || Kelley (9) || 18,531 || 40–35 || W1 |- style="background:#fbb;" | 76 || June 21 || White Sox || 4–5 || Herrera (3–3) || Kelley (3–2) || Colomé (16) || 29,333 || 40–36 || L1 |- style="background:#cfc;" | 77 || June 22 || White Sox || 6–5 || Lynn (9–4) || Marshall (3–1) || Martin (3) || 33,582 || 41–36 || W1 |- style="background:#cfc;" | 78 || June 23 || White Sox || 7–4 || Sampson (6–4) || Nova (3–6) || Kelley (10) || 21,917 || 42–36 || W2 |- style="background:#cfc;" | 79 || June 25 || @ Tigers || 5–3 || Chavez (3–2) || Zimmermann (0–5) || — || 18,952 || 43–36 || W3 |- style="background:#cfc;" | 80 || June 26 || @ Tigers || 4–1 || Minor (8–4) || Boyd (5–6) || — || 19,732 || 44–36 || W4 |- style="background:#cfc;" | 81 || June 27 || @ Tigers || 3–1 || Jurado (5–3) || Turnbull (3–8) || Kelley (11) || 22,925 || 45–36 || W5 |- style="background:#cfc;" | 82 || June 28 || @ Rays || 5–0 || Lynn (10–4) || Chirinos (7–4) || — || 13,955 || 46–36 || W6 |- style="background:#fbb;" | 83 || June 29 || @ Rays || 2–5 || McKay (1–0) || Sampson (6–5) || — || 16,655 || 46–37 || L1 |- style="background:#fbb;" | 84 || June 30 || @ Rays || 2–6 || Snell (5–7) || Chavez (3–3) || — || 11,234 || 46–38 || L2 |- |- style="background:#bbb;" | – || July 1 || Angels || colspan="9"| Postponed (death of Angels' P Tyler Skaggs); Rescheduled for August 20 as part of a doubleheader. |- style="background:#fbb;" | 85 || July 2 || Angels || 4–9 || Cahill (3–6) || Fairbanks (0–2) || — || 20,931 || 46–39 || L3 |- style="background:#fbb;" | 86 || July 3 || Angels || 2–6 ||