|-style=background:#fbb |37|| May 8 ||@ Padres || 2–3 || Reyes (2–0) || Bashlor (0–1) || Yates (15)|| Petco Park || 21,952 || 17–20 |-style=background:#bfb |38|| May 10||Marlins || 11–2 || Wheeler (3–2) || López (2–5) || — || Citi Field|| 25,194 || 18–20 |-style=background:#bfb |39|| May 11|| Marlins || 4–2 || deGrom (3–4) || Alcántara (1–4) || Díaz (10) || Citi Field|| 32,501 || 19–20 |-style=background:#bbb | — || May 12 || Marlins || colspan=7 | Postponed (inclement weather: rain). Makeup date: August 5th |-style=background:#bfb |40|| May 14||@ Nationals || 6–2 || Syndergaard (3–3) || Hellickson (2–2) || — || Nationals Park || 23,315 || 20–20 |-style=background:#fbb |41|| May 15||@ Nationals || 1–5 || Corbin (4–1) || Font (1–1) || — || Nationals Park || 29,673 || 20–21 |-style=background:#fbb |42|| May 16||@ Nationals || 6–7 || Jennings (1–2) || Wheeler (3–3) || Doolittle (7) || Nationals Park || 28,807 || 20–22 |-style=background:#fbb |43|| May 17||@ Marlins || 6–8 || Richards (1–5) || deGrom (3–5) || Romo (7) || Marlins Park || 9,870 || 20–23 |-style=background:#fbb |44|| May 18||@ Marlins || 0–2 || López (3–5) || Matz (3–3) || Conley (2) || Marlins Park || 13,474 || 20–24 |-style=background:#fbb |45|| May 19||@ Marlins || 0–3 || Alcántara (2–4) || Syndergaard (3–4) || — || Marlins Park || 15,983 || 20–25 |-style=background:#bfb |46|| May 20||Nationals || 5–3 || Gagnon (2–0) || Corbin (4–2) || Díaz (11) || Citi Field || 22,335 || 21–25 |-style=background:#bfb |47|| May 21||Nationals || 6–5 || Díaz (1–2) || Rainey (0–1) || — || Citi Field|| 24,631 || 22–25 |-style=background:#bfb |48|| May 22||Nationals || 6–1 || Gagnon (3–0) || Barraclough (0–1) || — || Citi Field|| 27,188 || 23–25 |-style=background:#bfb |49|| May 23||Nationals || 6–4 || Gsellman (1–0) || Suero (1–4) || Díaz (12) || Citi Field|| 29,962 || 24–25 |-style=background:#fbb |50|| May 24||Tigers || 8–9 || Farmer (3–3) || Gagnon (3–1) || Greene (16) || Citi Field|| 27,082 || 24–26 |-style=background:#bfb |51|| May 25||Tigers || 5–4 || Santiago (4–5) || Farmer (3–4) || — || Citi Field|| 40,691 || 25–26 |-style=background:#bfb |52|| May 26||Tigers || 4–3 || Wheeler (4–3) || Turnbull (2–4) || Díaz (13) || Citi Field|| 31,414 || 26–26 |-style=background:#fbb |53|| May 27||@ Dodgers || 5–9 || Kershaw (5–0) || Bashlor (0–2) || Jansen (15) || Dodger Stadium || 47,816 || 26–27 |-style=background:#bfb |54|| May 28||@ Dodgers || 7–3 || Matz (4-3) || Garcia (0-2)