|| 14½ |- style="text-align:center; background:#fbb;" | 56 || May 29 || @ Rays || 3–4 (11) || Castillo (1–3) || Shafer (0–1) || || 6,166 || 21–35 || 15½ |- style="text-align:center; background:#fbb;" | 57 || May 31 || @ Rockies || 6–13 || Márquez (6–2) || Jackson (0–3) || || 32,990 || 21–36 || 16½ |- |- style="text-align:center; background:#fbb;" | 58 || June 1 || @ Rockies || 2–4 || Gray (5–4) || Stroman (3–7) || Oberg (2) || 34,205 || 21–37 || 17½ |- style="text-align:center; background:#fbb;" | 59 || June 2 || @ Rockies || 1–5 || Senzatela (4–4) || Sanchez (3–6) || — || 37,861 || 21–38 || 17½ |- style="text-align:center; background:#bfb;" | 60 || June 4 || Yankees || 4–3 || Pannone (2–3) || Tanaka (3–5) ||Giles (11) || 20,671 || 22–38 || 16½ |- style="text-align:center; background:#bfb;" | 61 || June 5 || Yankees || 11–7 || Gaviglio (4–1) || Britton (2–1) || — || 16,609 || 23–38 || 15½ |- style="text-align:center; background:#fbb;" | 62 || June 6 || Yankees || 2–6 || Happ (6–3) || Jackson (0–4) || Chapman (18) || 25,657 || 23–39 || 16½ |- style="text-align:center; background:#fbb;" | 63 || June 7 || Diamondbacks || 2–8 || Kelly (6–6) || Stroman (3–8) || — || 16,555 || 23–40 || 16½ |- style="text-align:center; background:#fbb;" | 64 || June 8 || Diamondbacks || 0–6 || Greinke (7–2) || Sanchez (3–7) || — || 22,954 || 23–41 || 16½ |- style="text-align:center; background:#fbb;" | 65 || June 9 || Diamondbacks || 2–8 || Ray (5–3) || Richard (0–2) || — || 19,661 || 23–42 || 17½ |- style="text-align:center; background:#fbb;" | 66 || June 11 || @ Orioles || 2–4 || Means (6–4) || Thornton (1–5) || Givens (6) || 12,524 || 23–43 || 18 |- style="text-align:center; background:#bfb;" | 67 || June 12 || @ Orioles || 8–6 || Jackson (1–4)|| Hess (1–9) || Hudson (1) || 11,153 || 24–43 || 17½ |- style="text-align:center; background:#bfb;" | 68 || June 13 || @ Orioles || 12–3 || Stroman (4–8) || Ynoa (0–3) || — || 14,910 || 25–43 || 16½ |- style="text-align:center; background:#fbb;" | 69 || June 14 || @ Astros || 2–15 || Cole (6–5) || Sanchez (3–8) || Armenteros (1) || 34,719 || 25–44 || 17 |- style="text-align:center; background:#fbb;" | 70 || June 15 || @ Astros || 2–7 || Valdez (3–2) || Richard (0–3) || — ||