7 || @ Rockies || 14–4 || Bumgarner (2–4) || Senzatela (2–2) || – || 21,707 || 16–20 |-style=background:#fbb;" | 37 || May 8 || @ Rockies || 11–12 || Shaw (2–0) || Beede (0–1) || Davis (6) || 25,368 || 16–21 |-style=background:#bbb | – || May 9 || @ Rockies ||Colspan=7|Postponed (rain): Makeup date July 15 |-style=background:#fbb;" | 38 || May 10 || Reds || 0–7 || Castillo (4–1) || Rodríguez (3–5) || – || 32,191 || 16–22 |-style=background:#fbb | 39 || May 11 || Reds || 4–5 || Garrett (2–1) || Moronta (1–3) || Iglesias (8) || 32,829 || 16–23 |-style=background:#bfb;" | 40 || May 12 || Reds || 6–5 || Watson (2–0) || Hernandez (0–2) || Smith (10) || 35,824 || 17–23 |-style=background:#fbb | 41 || May 14 || Blue Jays || 3–7 || Thornton (1–4) || Vincent (0–2) || – || 31,230 || 17–24 |-style=background:#bfb;" | 42 || May 15 || Blue Jays || 4–3 || Melancon (1–0) || Tepera (0–2) || Smith (11) || 31,828 || 18–24 |-style=background:#fbb | 43 || May 17 || @ Diamondbacks || 0–7 || Kelly (4–4) || Samardzija (2–2) || – || 26,806 || 18–25 |-style=background:#bfb | 44 || May 18 || @ Diamondbacks || 8–5 || Bumgarner (3–4) || Godley (1–4) || – || 25,014 || 19–25 |-style=background:#bfb | 45 || May 19 || @ Diamondbacks || 3–2 || Dyson (2–0) || Hirano (1–2) || Smith (12) || 24,061 || 20–25 |-style=background:#fbb | 46 || May 20 || Braves || 1–4 || Soroka (5–1) || Suarez (0–1) || Newcomb (1) || 29,815 || 20–26 |-style=background:#bfb | 47 || May 21 || Braves || 4–3 || Gott (2–0) || Jackson (2–1) || || 28,030 || 21–26 |-style=background:#fbb | 48 || May 22 || Braves || 2–9 || Fried (7–2) || Samardzija (2–3) || || 31,402 || 21–27 |-style=background:#fbb | 49 || May 23 || Braves || 4–5 (13) || Jackson (3–1) || Moronta (1–4) || || 32,463 || 21–28 |-style=background:#fbb || 50 || May 24 || Diamondbacks || 2–18 || Ray (4–1) || Pomeranz (1–5) || Godley (2) || 31,777 || 21–29 |-style=background:#fbb | 51 || May 25 || Diamondbacks || 4–10 || Clarke (1–1) || Suarez (0–2) || – || 31,531 || 21–30 |-style=background:#fbb | 52 || May 26 || Diamondbacks || 2–6 || Weaver (4–3) || Anderson (0–1) || Holland (9) || 37,017 || 21–31 |-style=background:#fbb | 53