|| @ Braves || 9–6 || Hirano (1–1) || Minter (0–2) || Holland (3) || 22,407 || 8–9 || W2 |- align="center" bgcolor=ccffcc | 18 || April 17 || @ Braves || 3–2 || Bradley (1–1) || Biddle (0–1) || Holland (4) || 22,356 || 9–9 || W3 |- align="center" bgcolor=ccffcc | 19 || April 18 || @ Braves || 4–1 || Weaver (1–1) || Soroka (0–1) || Hirano (1) || 24,193 || 10–9 || W4 |- align="center" bgcolor=ffbbbb | 20 || April 19 || @ Cubs || 1–5 || Hendricks (1–3) || Kelly (1–2) || Strop (2) || 33,938 || 10–10 || L1 |- align="center" bgcolor=ccffcc | 21 || April 20 || @ Cubs || 6–0 || Greinke (3–1) || Darvish (1–3) || Clarke (1) || 37,667 || 11–10 || W1 |- align="center" bgcolor=ffbbbb | 22 || April 21 || @ Cubs || 1–2 || Strop (1–1) || Bradley (1–2) || — || 38,181 || 11–11 || L1 |- align="center" bgcolor=ccffcc | 23 || April 22 || @ Pirates || 12–4 || Andriese (3–1) || Crick (0–1) || — || 9,233 || 12–11 || W1 |- align="center" bgcolor=ccffcc | 24 || April 23 || @ Pirates || 2–1 || Weaver (2–1) || Williams (1–1) || Holland (5) || 8,558 || 13–11 || W2 |- align="center" bgcolor=ccffcc | 25 || April 24 || @ Pirates || 11–2 || Kelly (2–2) || Lyles (2–1) || — || 9,450 || 14–11 || W3 |- align="center" bgcolor=ccffcc | 26 || April 25 || @ Pirates || 5–0 || Greinke (4–1) || Taillon (1–3) || — || 9,365 || 15–11 || W4 |- align="center" bgcolor=ccffcc | 27 || April 26 || Cubs || 8–3 || Ray (1–1) || Hendricks (1–4) || Andriese (1) || 30,664 || 16–11 || W5 |- align="center" bgcolor=ffbbbb | 28 || April 27 || Cubs || 1–9 || Darvish (2–3) || Godley (1–2) || — || 27,793 || 16–12 || L1 |- align="center" bgcolor=ffbbbb | 29 || April 28 || Cubs || 5–6 (15) || Chatwood (1–0) || Andriese (3–2) || Webster (1) || 29,477 || 16–13 || L2 |- align=“center” bgcolor=ccffcc | 30 || April 30 || Yankees || 3–1 || Greinke (5–1) || Sabathia (1–1) || Holland (6) || 36,352 || 17–13 || W1 |- |- align=“center” bgcolor=ccffcc | 31 || May 1 || Yankees || 3–2 || Kelly (3–2) || Tanaka (2–3) || Holland (7) || 31,365