|| 41–40 || W3 |-style=background:#bfb;" ||82|| June 29 || Cardinals || 12–2 || Paddack (5–4) || Hudson (6–4) || — || 44,407 || 42–40 || W4 |-style=background:#fbb;" ||83|| June 30 || Cardinals || 3–5 || Martínez (2–0) || Wieck (0–1) || Leone (1) || || 42–41 || L1 |- |-style=background:#fbb;" ||84|| July 1 || Giants || 2–13 || Samardzija (5–7) || Allen (2–1) || — || 25,274 || 42–42 || L2 |-style=background:#fbb;" ||85|| July 2 || Giants || 4–10 || Beede (2–3) || Strahm (3–7) || — || 24,007 || 42–43 || L3 |-style=background:#fbb;" ||86|| July 3 || Giants || 5–7 || Gott (5–0) || Perdomo (1–1) || Smith (22) || 33,905 || 42–44 || L4 |-style=background:#fbb;" ||87|| July 4 || @ Dodgers || 1–5 || Ryu (10–2) || Lamet (0–1) || — || 53,801 || 42–45 || L5 |-style=background:#bfb;" ||88|| July 5 || @ Dodgers || 3–2 || Stammen (6–4) || García (1–3) || Yates (28) || 49,790 || 43–45 || W1 |-style=background:#bfb;" ||89|| July 6 || @ Dodgers || 3–1 || Wingenter (1–1) || Maeda (7–5) || Yates (29) || 53,610 || 44–45 || W2 |-style=background:#bfb;" ||90|| July 7 || @ Dodgers || 5–3 || Lucchesi (7–4) || Stripling (3–3) || Yates (30) || 44,171 || 45–45 || W3 |-style="text-align:center; background:#bbcaff;" | colspan="10"|90th All-Star Game in Cleveland, OH |-style="text-align:center; background:#bbcaff;" | colspan=10 |Representing the Padres: Kirby Yates |-style=background:#fbb;" ||91|| July 12 || Braves || 3–5 || Keuchel (3–2) || Lamet (0–2) || Jackson (15) || 34,692 || 45–46 || L1 |-style=background:#fbb;" ||92|| July 13 || Braves || 5–7 || Newcomb (3–1) || Perdomo (1–2) || Jackson (16) || 43,148 || 45–47 || L2 |-style=background:#fbb;" ||93|| July 14 || Braves || 1–4 || Soroka (10–1) || Wingenter (1–2) || Minter (5) || 34,739 || 45–48 || L3 |-style=background:#fbb;" ||94|| July 16 || @ Marlins || 7–12 || Yamamoto (4–0) || Allen (2–2) || — || 8,151 || 45–49 || L4 |-style=background:#bfb;" ||95|| July 17 || @ Marlins || 3–2 || Paddack (6–4) || Richards (3–11) || Yates (31) || 7,818 || 46–49 || W1 |-style=background:#fbb;" ||96|| July 18 || @ Marlins || 3–4 || Romo (2–0) || Wingenter (1–3) || — || 21,149 || 46–50 || L1 |-style=background:#fbb;" ||97|| July 19 || @ Cubs || 5–6 || Strop (2–3) || Stammen (6–5) || Kimbrel (5) || 39,526 || 46–51 || L2 |-style=background:#fbb;" ||98|| July 20 || @ Cubs ||