|| Ramirez (3–0) || Diekman (0–3) || Greene (20) || 19,870 || 21–46|| L1 |-style=background:#bfb ||68|| June 13 || Tigers (Game played in Omaha) || 7–3 || Bailey (5–6) || Boyd (5–5) || Kennedy (6) || 25,454 || 22–46 || W1 |-style=background:#fbb ||69|| June 14 || @ Twins || 0–2 || Gibson (7–3) || Diekman (0–4) || Rogers (7) || 38,898 || 22–47 || L1 |-style=background:#fbb ||70|| June 15 || @ Twins || 4–5 || Odorizzi (10–2) || Sparkman (1–3) || Rogers (8) || 39,267 || 22–48 || L2 |-style=background:#bfb ||71|| June 16 || @ Twins || 8–6 || López (1–6) || Pérez (7–3) || Kennedy (7) || 38,886 || 23–48|| W1 |-style=background:#bfb ||72|| June 17 || @ Mariners || 6–4 || Flynn (1–0) || Bass (1–2) || Kennedy (8) || 14,476 || 24–48 || W2 |-style=background:#bfb ||73|| June 18 || @ Mariners || 9–0 || Bailey (6–6) || Kikuchi (3–5) ||-|| 12,697 || 25–48 || W3 |-style=background:#fbb ||74|| June 19 || @ Mariners || 8–2 || Gonzales (8–6) || Keller (3–9) ||-|| 16,228 || 25–49|| L1 |-style=background:#bfb ||75|| June 20 || Twins || 4–1 || Sparkman (2–3) || Odorizzi (10–3) || Kennedy (9) || 22,683 || 26–49 || W1 |-style=background:#fbb ||76|| June 21 || Twins || 7–8 || Harper (3–0) || Diekman (0–5) || Rogers (9) || 27,418 || 26–50 || L1 |-style=background:#fbb ||77|| June 22 || Twins || 3–5 || May (2–1) || Peralta (2–3) || Parker (10) || 28,504 || 26–51 || L2 |-style=background:#bfb ||78|| June 23 || Twins || 6–1 || Bailey (7–6) || Pineda (4–4) || McCarthy (1) || 21,257 || 27–51 || W1 |-style=background:#fbb ||79|| June 24 || @ Indians || 2–3 || Hand (4–2) || Peralta (2–4) ||-|| 15,413 || 27–52 || L1 |-style=background:#bfb ||80|| June 25 || @ Indians || 8–6 || McCarthy (2–1) || Hand (4–3) || Kennedy (10) || 21,766 || 28–52 || W1 |-style=background:#fbb ||81|| June 26 || @ Indians || 3–5 || Bauer (6–6) || Junis (4–7) ||-|| 22,246 || 28–53 || L1 |-style=background:#fbb ||82|| June 28 || @ Blue Jays || 2–6 || Hudson (4–2) || Duffy (3–4) ||-|| 18,399 || 28–54 || L2 |-style=background:#fbb ||83|| June 29 || @ Blue Jays || 5–7 || Hudson (5–2) || Barlow (2–3) ||-|| 24,906 || 28–55 || L3 |-style=background:#bfb ||84|| June 30 || @ Blue Jays || 7–6 || Keller (4–9) || Sanchez (3–11) || Kennedy (11) || 21,727