Stadium || 40,523 || 11–10 |-style=background:#bfb | 22 || April 22 || @ Angels || 4–3 || Holder (1–0) || Bard (0–1) || — || Angel Stadium || 35,403 || 12–10 |-style=background:#bfb | 23 || April 23 || @ Angels || 7–5 || Germán (4–1)|| Stratton (0–2) || Britton (1) || Angel Stadium || 38,016 || 13–10 |-style=background:#bfb | 24 || April 24 || @ Angels || 6–5 || Loáisiga (1–0) || Buttrey (1–1) || Chapman (4) || Angel Stadium || 37,928 || 14–10 |-style=background:#fbb | 25 || April 25 || @ Angels || 5–11 || Ramirez (1–0)|| Tanaka (2–2) || — || Angel Stadium || 39,584 || 14–11 |-style=background:#bfb | 26 || April 26 || @ Giants || 7–3 || Paxton (3–2) || Bumgarner (1–4) || — || Oracle Park || 34,950 || 15–11 |-style=background:#bfb | 27 || April 27 || @ Giants || 6–4 || Happ (1–2)|| Holland (1–4) || Chapman (5) || Oracle Park ||33,971 || 16–11 |-style=background:#bfb | 28 || April 28 || @ Giants || 11–5 || Germán (5–1) || Rodríguez (3–3) || — || Oracle Park || 34,540 || 17–11 |-style=background:#fbb | 29 || April 30 || @ Diamondbacks || 1–3 || Greinke (5–1) || Sabathia (1–1) || Holland (6) || Chase Field || 36,352 || 17–12 |- |-style=background:#fbb | 30 || May 1 || @ Diamondbacks || 2–3 || Kelly (3–2) || Tanaka (2–3) || Holland (7) || Chase Field || 31,365 || 17–13 |-style=background:#bfb | 31 || May 3 || Twins || 6–3 || Holder (2–0) || Gibson (2–1) || Chapman (6) || Yankee Stadium || 35,911 || 18–13 |-style=background:#fbb | 32 || May 4 || Twins || 3–7 || Odorizzi (4–2) || Happ (1–3) || — || Yankee Stadium || 43,123 || 18–14 |-style=background:#bfb | 33 || May 5 || Twins || 4–1 || Germán (6–1) || Pineda (2–3) || Chapman (7) || Yankee Stadium || 38,603 || 19–14 |-style=background:#bfb | 34 || May 6 || Mariners || 7–3 || Sabathia (2–1) || Hernández (1–3) || — || Yankee Stadium || 37,423 || 20–14 |-style=background:#bfb | 35 || May 7 || Mariners || 5–4 || Harvey (1–0) || Swarzak (2–2) || — || Yankee Stadium || 36,851 || 21–14 |-style=background:#fbb | 36 || May 8 || Mariners || 1–10 || Kikuchi (2–1) || Loáisiga (1–1) || — || Yankee Stadium || 38,774 || 21–15 |-style=background:#bfb | 37 || May 9 ||