|| Colomé (18) || 27,244 || 39–42 || W1 |- |-style=background:#bbb || — || July 2 || Tigers || 7:10pm ||colspan=8| Postponed (Inclement Weather, makeup date on September 27) |-style=background:#bfb || 82 || July 3 || Tigers || 1:10pm || 7–5 || Cease (1–0) || Norris (2–8) || Colomé (19) || 26,023 || 40–42 || W2 |-style=background:#bfb || 83 || July 3 || Tigers || 7:10pm || 9–6 || Ruiz (1–1) || Ramirez (3–3) || — || 23,161 || 41–42 || W3 |-style=background:#fbb || 84 || July 4 || Tigers || 1:10pm || 5–11 || Boyd (6–6) || López (4–8) || — || 25,617 || 41–43 || L1 |-style=background:#fbb || 85 || July 6 || Cubs || 6:15pm || 3–6 || Lester (8–6) || Giolito (11–3) || Kimbrel (2) || 38,634 || 41–44 || L2 |-style=background:#bfb || 86 || July 7 || Cubs || 1:10pm || 3–1 || Nova (4–7) || Hendricks (7–7) || Colomé (20) || 38,554 || 42–44 || W1 |-style=background:#bbbfff || — || July 9 || colspan="10"|90th All-Star Game in Cleveland, OH |-style=background:#fbb || 87 || July 12 || @ Athletics || 9:07pm || 1–5 || Fiers (9–3) || Nova (4–8) || Hendriks (6) || 18,504 || 42–45 || L1 |-style=background:#fbb || 88 || July 13 || @ Athletics || 3:07pm || 2–13 || Bassitt (6–4) || Covey (1–5) || — || 22,222 || 42–46 || L2 |-style=background:#fbb || 89 || July 14 || @ Athletics || 3:07pm || 2–3 || Hendriks (4–0) || Fry (1–4) || — || 20,350 || 42–47 || L3 |-style=background:#fbb || 90 || July 15 || @ Royals || 7:15pm || 2–5 || Junis (5–8) || Giolito (11–4) || Kennedy (14) || 16,006 || 42–48 || L4 |-style=background:#fbb || 91 || July 16 || @ Royals || 7:15pm || 0–11 || Sparkman (3–5) || Cease (1–1) || — || 16,557 || 42–49 || L5 |-style=background:#fbb || 92 || July 17 || @ Royals || 7:15pm || 5–7 || Duffy (4–5) || Nova (4–9) || Kennedy (15) || 14,340 || 42–50 || L6 |-style=background:#fbb || 93 || July 18 || @ Royals || 12:15pm || 5–6 || Keller (6–9) || Detwiler (1–1) || Kennedy (16) || 13,157 || 42–51 || L7 |-style=background:#bfb || 94 || July 19 || @ Rays || 6:10pm || 9–2 || López (5–8) || McKay (1–1) || — || 16,971 || 43–51 || W1 |-style=background:#bfb || 95 || July