The surname O'Loughlin is an Anglicised form of the Irish Ó Lochlainn meaning "descendant of Lochlann". People with the surname Alex O'Loughlin (born 1976), Australia-born actor Charlie O'Loughlin, English football defender Chris O'Loughlin (fencer) (born 1967), American Olympic fencer David O'Loughlin, Irish cyclist Gerald S. O'Loughlin (1921–2015), American actor Harold J. O'Loughlin (1900-1968), American lawyer, businessman, and politician Jack O'Loughlin (Australian footballer) (1873–1960) Laurence O'Loughlin (1854–1927), South Australian politician Marina O'Loughlin, British journalist, writer and restaurant critic Michael O'Loughlin (born 1977), Australian rules footballer Sean O'Loughlin (born 1982), English professional rugby league footballer Silk O'Loughlin (1872–1918), American baseball umpire Thomas O'Loughlin, Professor of Historical Theology Vanessa O'Loughlin, British-born writer and literary agent References Anglicised Irish-language surnames Surnames of Irish origin