1957 and 1960, he held training posts at the National Hospital for Neurology and Neurosurgery at Queen Square, and was then appointed as a senior registrar in neurology at St George's Hospital at Hyde Park Corner, where he worked under neurologist Denis Williams, and at Atkinson Morley Hospital, part of St George's, where he made a reputation for himself working with neurosurgeon Wylie McKissock. Later in 1960, he trained at the University of California, San Francisco, under neurologist Robert B. Aird for six months, then spent three months at Pitié-Salpêtrière Hospital in Paris the following year. In 1963, after turning down a job at the University of Rochester he returned to England to become consultant in neurology at the Royal Eye Medical Ophthalmology Unit at the Lambeth Hospital, where he was part of a team of three physicians including Geraint James. He also kept sessions at St. Thomas's Hospital. In 1965 he became the first consultant in neurology at Charing Cross Hospital, where he also founded its Academic Unit. His private practice was based in Harley Street. Rose had an interest in neuro-ophthalmology and his research contributed to the understanding of aphasiology. He made significant contributions to the management of motor neurone disease, stroke and migraine, three areas of neurology which became increasingly important over time. He developed an emergency stroke ambulance service with early neuroimaging, allowing for the detection of early reversible brain damage. In 1974, he established a specialist clinic for headache at Charing Cross. Six years later, it became the Princess Margaret Migraine Clinic, a move endorsed by his friend MacDonald Critchley. With regards to the role of alcohol and headaches, following his study of the effect of red wine on preselected red wine sensitive migraine sufferers, he stated that red wine could trigger a migraine, but any alcohol might provoke a headache. Other roles Rose was the secretary-treasurer general of the World Federation of Neurology (WFN) when its president was John Walton. He was the first editor-in-chief of World Neurology, founding editor of the Journal of the History of the Neurosciences, and founding chair of the WFN's Research Group on the History of the Neurosciences. He co-edited Headache Quarterly from 1980 to 2001 and was editor-in-chief of the journals Neuroepidemiology from 1984 to 1990 and Transactions of the Medical Society of London from 1980 to 1986. He played a significant part in the foundation of the