his Lizard persona, with the chip acting as an inhibitor that stopped him from attacking humans. Teaching once again, Connors offered to support Peter Parker's efforts to re-apply for his doctorate after he was academically disgraced by accusations of plagiarism of Otto Octavius' thesis since Doctor Octopus' mind was in Peter's body at the time. The inhibitor proved to be a disadvantage when Connors' class was attacked by the Taskmaster and the Black Ant and he could not defend himself. When Connors was captured by Kraven the Hunter as part of his organized hunt for various animal-themed villains, he was locked in a cell with Spider-Man while the two of them watched live footage of the Black Cat and the Lizard-esque Billy Connors being hunted, with Billy admitting that he actually remembers his original death. Faced with a threat to his son, Connors asked Spider-Man to tear out the inhibitor chip so that he could rescue his son, despite the risk of this action leaving Connors paralyzed at best, the two unaware that Kraven had set the situation up precisely to force Spider-Man into a position where he would become the ruthless warrior that Kraven believes that he 'should' be. However, Connors managed to maintain control and retrieve Billy without killing anyone. In a prelude to the "Sinister War" storyline, Doctor Octopus coerced Curt Connors into using the Isotope Genome Accelerator on himself which separates him from his Lizard side. Kindred then completed the Sinister Six by having Mysterio join him as Kindred notes that his endgame with Spider-Man is approaching. Spider-Man found Connors in his wrecked lab as he was informed on what happened. Peter then took Connors home in the sewer to recover with his family. Spider-Man suspects that Doctor Octopus is forming his latest incarnation of the Sinister Six. Lizard's Isotope Genome Accelerator duplicate and the rest of the Sinister Six proceeded to compete with the other villains that Kindred enlisted to take out Spider-Man. Doctor Octopus managed to have all the villains subdued when he hacked into Black Ant's helmet by changing the setting to centipedes which affected the centipedes in every villains' head. During the "Beyond" storyline, Maxine Danger of the Beyond Corporation sent Misty Knight and Colleen Wing into the sewers where they apprehended Lizards' Isotope Genome Accelerator duplicate. Upon being taken to Beyond Corporation's secret facility on Staten Island, the genetic template of