in the healthy eye or, on the other hand, to activate the immune system in the case of disease. Pathology In the eyes of albinos, the cells of this layer contain no pigment. Dysfunction of the RPE is found in age-related macular degeneration and retinitis pigmentosa. RPE are also involved in diabetic retinopathy. Gardner syndrome is characterized by FAP (familial adenomatous polyps), osseous and soft tissue tumors, retinal pigment epithelium hypertrophy and impacted teeth. See also Bruch's membrane Drusen Fovea centralis Fundus (eye) Macula of retina References Further reading External links Human eye anatomy