Tezuka as a member of the second-generation Seigaku cast. He made his debut as Tezuka on January 8, 2005, in the Side Yamabuki performance in Osaka. That same year, his role as Tezuka was carried into the live adaptation film of the manga and marked his first major film appearance. He also released a Best Actor's album in 2005, for his role as Tezuka. On March 29, 2006, in the Dream Live 3rd Live concert, he along with the majority of the second generation Seigaku cast, graduated from their roles. Through 2006, Shirota began appearing in a couple dramas and movies including the 2005 Watanabe net drama, Hice Cool, the TV drama special, The Hit Parade, portraying the real-life Mickey Curtis and the June Bride movie in which he played the title character, Natsumi, based on the original manga Jyun Bride by Satoshi Yoshida, resulted in a made for DVD release sequel, Zoku June Bride. In 2007, after nearly a year away from musicals, Shirota returned to stage and starred as Anthony Hope, the cheerful young sailor, in the Japanese stage production of Sweeney Todd. The musical opened on January 5, 2007 and ran through January 29, 2007, at the Nissay Theatre with additional performances during February in Osaka. Shirota then began appearing in a string of dramas, the first being the TV drama, Dignity of Haken, featured Shirota as the half-Spanish Ryuto Amaya, premiered on January 10, 2007, on NTV and ended its run on March 21, 2007. Shirota next appeared in his second TV drama appearance, in the April 2007 drama, Seito Shokun!, which is an adaptation of the manga series, Seito Shokun. He played Ken Mizuhara, a physical education teacher. In his third TV drama role of the year, Shirota appeared in the popular adaptation of Hanazakari No Kimitachi e, which began on July 3, 2007, playing the character of Kagurazaka Makoto, a high-jumping rival to Sano Izumi. Shirota also appeared in a string of films in 2007. The first being Arakure KNIGHT, the live-action movie adaptation of the 1982 to 1988 manga series, Aratanaru Shobaku by Satosi Yoshida. The film opened in limited release, premiering at Cinema GAGA on April 28, 2007. The second of his three films, Shirota played a main supporting actor in the film adaptation of Gettsu Itaya's semi-autobiographical novel, Waruboro and was released on September 8, 2007, as principal filmography began on