others. ICL may indirectly trigger autoimmune diseases. It has been associated with several cases of autoimmune disease Sjögren syndrome. Because all of the reported autoimmune diseases and lymphomas involve B cells, one hypothesis proposes that ICL's narrow T cell repertoire predisposes the immune system to B cell disorders. Epidemiology ICL is a very rare disease. In 1993, a total of 47 confirmed cases were reported in a survey sponsored by the Centers for Disease Control. References External links Rare diseases Immune system disorders Immunodeficiency