1989, and the Tom Hanks vehicle Turner & Hooch in 1989. In 1988, Winningham also starred in the Los Angeles stage production of Hurlyburly with Sean Penn and Danny Aiello. In the early 1990s, she returned to film for 1994's all-star Wyatt Earp and the family drama The War, both starring Kevin Costner. 1995 brought Georgia, a thoughtful character study of two sisters (Winningham and Jennifer Jason Leigh), which earned Winningham Screen Actors Guild and Academy Award nominations. Two years later, she starred opposite Gary Sinise in George Wallace, for which she garnered her Golden Globe Award nomination and won an Emmy Award. She made acclaimed appearances on the series ER and Law & Order: Special Victims Unit, as well as appearances in the 2001 television project Sally Hemings opposite Sam Neill and the short-lived David E. Kelley series The Brotherhood of Poland, New Hampshire. Also in 2001, she appeared in the made-for-TV movie Snap Decision with Felicity Huffman. She also appeared in the independent film Dandelion, which was a staple of film festivals worldwide between 2003 and 2004 and had a limited American release in October 2005. In 2006, she landed the role of Susan Grey on the ABC drama Grey's Anatomy where she played the stepmother of one of the main characters, Dr. Meredith Grey. Her character was killed off in May 2007. In 2006, Winningham voiced the audio version of Stephen King's Lisey's Story. In 2007, she voiced Alice Hoffman's Skylight Confessions. In 2010, Winningham starred in an episode of Cold Case as main character Lilly Rush's stepmother, Celeste Cooper. In 2011 she appeared in the fourth episode of Torchwood: Miracle Day as character Ellis Hartley Monroe. She also starred in miniseries Mildred Pierce and Hatfields & McCoys and garnered another two Emmy nominations. In 2012, she appeared Off-Broadway as Beth, the mother in an intellectual, though dysfunctional, British family, in the award-winning comic-drama Tribes by Nina Raine. In 2021 she appeared in Dopesick on Hulu with Michael Keaton. In 2022, she was nominated for a second Tony for her leading performance in Girl from the North Country. Music Winningham has alternated her film career with a music career, and has used some of her films as a way to showcase her singing. She can be heard singing a few bars of "Me and Bobby McGee" in One Trick Pony. In 1981, she played a teenage runaway