a double bass player for the Boston Symphony Orchestra The Handmaid's Tale, takes place in Boston following the establishment of a neo-Puritanic totalitarian state, Gilead. The Practice, centered on a Boston law firm, also created by David E. Kelley Rizzoli & Isles, drama starring Angie Harmon as Police Detective Jane Rizzoli and Sasha Alexander as Medical Examiner Dr. Maura Isles Sabrina, the Teenage Witch St. Elsewhere, drama set in the fictional St. Eligius Hospital in Boston Spenser: For Hire, featuring Robert Urich playing the Robert B. Parker character Suite Life of Zack & Cody, comedy made for the younger audience; takes place in a fictional hotel in Boston survivors remorse, the family is from dorchester Two Guys and a Girl Unhitched, about a group of newly single friends learning the lessons of starting over in their 30s The X-Files, in "Medusa" (Episode 12 of Season 8), Agents Doggett and Scully investigate suspicious deaths on the Boston subway system Film A number of films have been set in Boston or Greater Boston. 21, a fictionalized account of the very-unofficial MIT Blackjack Team Altered States, Ken Russell film based on Paddy Chayefsky's novel Between the Lines Black Mass, about the criminal career of infamous Irish-American mobster Whitey Bulger Blown Away, depicts the Boston Bomb Squad dealing with a mad bomber Blue Hill Avenue, about four childhood friends from Dorchester who grow up to become drug dealers The Boondock Saints, about two Irish immigrant brothers in Boston who become vigilantes The Boondock Saints II: All Saints Day, sequel to The Boondock Saints, in which the brothers are forced to return to Boston The Boston Strangler, depicting a famous serial killer, played by Tony Curtis The Bostonians The Brink's Job, about the famous robbery of the Brinks security transport in the North End Celtic Pride, about two diehard Boston Celtics fans Charly, based on Flowers for Algernon, about a mentally challenged man who receives treatment for his disability A Civil Action, about several families who attempt to sue a company for dumping toxic waste that gave their children leukemia; filmed all over Boston, ironically not in Woburn, where it takes place, but in Palmer Coma is set at the fictional Boston Memorial Hospital The Company Men, starring Ben Affleck, Chris Cooper, Tommy Lee Jones and Kevin Costner The Core, in an early scene, people with pacemakers mysteriously drop dead during Green World Day; it