Uptown Memphis is a neighborhood located near downtown Memphis, Tennessee. In 1999, the Uptown Partnership renamed the historic North Memphis Greenlaw neighborhood "Uptown" in concert with a public-private revitalization effort that defined Uptown as one hundred city blocks east of the Wolf River and North of A.W. Willis Avenue. The historic Greenlaw section of this neighborhood consists of the thirty city blocks closest to the Wolf River (bordered by A.W. Willis Avenue to the south, North Seventh Street to the east, Keel Avenue and Chelsea Avenue to the north and the Wolf River to the west). Areas adjacent to Uptown include St. Jude Children's Research Hospital and the Pinch District. History 19th century In 1856, Greenlaw Addition was laid out by William B. Greenlaw, John O. Greenlaw, Robert F. Looney, John L. Saffarans, Isaac Saffarans and E.T. Keel. They owned the land north of Memphis across Bayou Gaoyoso from downtown.The Bayou was the original northern boundary of the City of Memphis. The thirty block subdivision extended the grid patterns of downtown Memphis and included many desirable features such as cobbled streets, granite curbs, and boulevards lined with sycamore trees. The names of the founders are familiar as the east-west streets honor them: Greenlaw, Saffarans, Looney, and Keel. Mill Street was named due for the mills that occupied the adjacent riverfront. The namesakes of this new addition, the Greenlaw Brothers, arrived in Memphis during the city's early days. They built open-air markets in the downtown. The other partners in the project were prominent Memphis businessmen in the 1850s: Robert Looney operated a dry goods store, John Saffarans owned a building supply company and sawmill and E.T. Keel owned grocery stores and property. Many of the original Greenlaw residents were also prominent Memphis businessmen and citizens while many other residents were construction tradesmen By the Civil War the area was prospering as remaining lots were developed and sawmills, brickyards and breweries were built on the river's banks. In 1870, Greenlaw and Chelsea were annexed into Memphis. Once Memphis recovered from the devastating effects of the Civil War, Greenlaw witnessed a major commercial and residential development. Neighborhood businesses concentrated along North Second Street as the area west of North Main became more industrial. Residences included a mix of larger homes on prominent corner locations, smaller duplexes on the inside blocks and shotgun style homes on the alleyways and near the bayou. Originally named