in the 1994 film adaptation of Little Women, and in How to Make an American Quilt (1995), both starring Winona Ryder. She then appeared in The American President (1995), playing the assistant to the President of the United States. Mathis costarred with Christian Slater again, along with John Travolta, in John Woo's Broken Arrow (1996). She took a little over a year off from acting after her mother died in 1996 from breast cancer. Mathis later appeared in American Psycho (2000), a film adaptation of Bret Easton Ellis's 1991 novel of the same name. She starred in Attraction (2000) and in The Simian Line (2001). She starred in the TNT television miniseries The Mists of Avalon (2001). Mathis starred with Thomas Jane in The Punisher (2004). She had a guest role on the ABC television show Lost as Olivia Goodspeed. She played Jane Fonda's daughter in the Broadway show "33 Variations." Her indie film Lebanon, PA had its world premiere at the 2010 SXSW Film Festival. She appeared in an off-Broadway production of the play, Love, Loss, and What I Wore, at New York City's Westside Theatre in October 2011. In 2013, Mathis played psychiatrist Alice Calvert on the CBS television series Under the Dome, based on a novel by Stephen King. In 2014, she joined the cast of the FX horror drama series The Strain as Justine Feraldo, a New York City councilwoman for Staten Island. In October 2015, Mathias was elected National Vice President, Actors/Performers of SAG-AFTRA. She was re-elected in 2017. In 2019, she appeared Off-Broadway in the role of Kate Conlee in Make Believe, a new play by Bess Wohl staged at the Second Stage Theater. Michael Greif directed. Her 2020 musical Whisper House was postponed due to the COVID-19 pandemic. Personal life Mathis met actor River Phoenix on the set of the 1993 film The Thing Called Love. Soon thereafter, she broke up with boyfriend John Leguizamo and started a relationship with Phoenix. She was with Phoenix on October 31, 1993, the night he died at Cedars-Sinai Hospital of a drug overdose after collapsing outside The Viper Room in West Hollywood, California. In the autopsy report, the LASD detailed that Mathis refused several times to give more details surrounding the death of Phoenix and had told deputies at the time of Phoenix's death that she had no knowledge of his drug use. Mathis took a