is no evidence to support these concerns." As of August 2021, such demands are rare in the US. Doctors in Alberta, Canada, warned in November 2022 that the demands were becoming more common. In Italy and New Zealand, parents have gone to court to stop their children's urgent heart surgery, unless COVID-19 vaccine free blood was provided. In both cases the parents were ruled against, though they stated that they could provide willing donors they found acceptable. The New Zealand Blood Service does not label blood according to the donor's COVID-19 vaccine history, and as of 2022, about 90% of New Zealand's population over twelve years of age has had two COVID-19 vaccinations. In another Italian case, a blood transfusion for a sick 90-year-old man was refused by his two daughters, due to vaccine hesitancy concerns. Another New Zealand couple stated that they were trying to arrange their child to have her next heart surgery in India, to avoid her being given blood from COVID-19 vaccinated donors. Other safety concerns Other safety concerns about vaccines have been promoted on the Internet, in informal meetings, in books, and at symposia. These include hypotheses that vaccination can cause epileptic seizures, allergies, multiple sclerosis, and autoimmune diseases such as type1 diabetes, as well as hypotheses that vaccinations can transmit bovine spongiform encephalopathy, hepatitis C virus, and HIV. These hypotheses have been investigated, with the conclusion that currently used vaccines meet high safety standards and that criticism of vaccine safety in the popular press is not justified. Large well-controlled epidemiologic studies have been conducted and the results do not support the hypothesis that vaccines cause chronic diseases. Furthermore, some vaccines are probably more likely to prevent or modify than cause or exacerbate autoimmune diseases. Another common concern parents often have is about the pain associated with administering vaccines during a doctor's office visit. This may lead to parental requests to space out vaccinations; however, studies have shown a child's stress response is not different when receiving one vaccination or two. The act of spacing out vaccinations may actually lead to more stressful stimuli for the child. Psychology The rise in vaccine hesitancy has led to research on the psychology of those who oppose vaccines. A 24-nation investigation led by the University of Queensland and reported in Health Psychology in 2018 found that the largest psychological factors leading to anti-vaccination attitudes were conspiratorial thinking, reactance,