to anaerobic conditions. This can lead to increased bacteria levels when there is ample food supply. Many aquatic species will fail to reproduce at elevated temperatures. Primary producers (e.g. plants, cyanobacteria) are affected by warm water because higher water temperature increases plant growth rates, resulting in a shorter lifespan and species overpopulation. The increased temperature can also change the balance of microbial growth, including the rate of algae blooms which reduce dissolved oxygen concentrations. Temperature changes of even one to two degrees Celsius can cause significant changes in organism metabolism and other adverse cellular biology effects. Principal adverse changes can include rendering cell walls less permeable to necessary osmosis, coagulation of cell proteins, and alteration of enzyme metabolism. These cellular level effects can adversely affect mortality and reproduction. A large increase in temperature can lead to the denaturing of life-supporting enzymes by breaking down hydrogen- and disulphide bonds within the quaternary structure of the enzymes. Decreased enzyme activity in aquatic organisms can cause problems such as the inability to break down lipids, which leads to malnutrition. Increased water temperature can also increase the solubility and kinetics of metals, which can increase the uptake of heavy metals by aquatic organisms. This can lead to toxic outcomes for these species, as well as build up of heavy metals in higher trophic levels in the food chain, increasing human exposures via dietary ingestion. In limited cases, warm water has little deleterious effect and may even lead to improved function of the receiving aquatic ecosystem. This phenomenon is seen especially in seasonal waters. An extreme case is derived from the aggregational habits of the manatee, which often uses power plant discharge sites during winter. Projections suggest that manatee populations would decline upon the removal of these discharges. Cold water Releases of unnaturally cold water from reservoirs can dramatically change the fish and macroinvertebrate fauna of rivers, and reduce river productivity. In Australia, where many rivers have warmer temperature regimes, native fish species have been eliminated, and macroinvertebrate fauna have been drastically altered. Survival rates of fish have dropped up to 75% due to cold water releases. Thermal shock When a power plant first opens or shuts down for repair or other causes, fish and other organisms adapted to particular temperature range can be killed by the abrupt change in water temperature, either an increase or decrease, known as "thermal shock". Biogeochemical effects Water warming