Patrick, and Nicholai Ginovaef—have set up subway trains to evacuate civilians from the city. Jill helps them reactivate power to the subway and departs on a train with Nicholai and Mikhail, while Carlos and Tyrell remain behind to find Dr. Nathaniel Bard, an Umbrella scientist who may have developed a vaccine for the T-virus. After Mikhail expresses his suspicions towards Nicholai over how their platoon was ambushed by zombies, Nemesis attacks the train and kills the civilians. Nicholai then betrays and locks Jill and Mikhail out, with the latter sacrificing himself by detonating an explosive that derails the train. Meanwhile, reaching the police department on the notion that Bard is at the S.T.A.R.S. office, Carlos and Tyrell learn the scientist took refuge at a nearby hospital. Carlos is then contacted by Jill, who survived the crash while being pursued by a mutating Nemesis. She manages to escape Nemesis, only to lose consciousness after the monster infects her with the T-virus. Carlos finds Jill half a day later and takes her to the hospital, finding Bard murdered along with the scientist's video entry revealing that Umbrella's board is wiping out the vaccines and any evidence connecting the company to the T-Virus. After Carlos retrieves Bard's vaccine and administers it to Jill, Tyrell discovers that the U.S. government plans to destroy Raccoon City in a missile strike to eradicate the T-virus infestation. Carlos travels to a lab underneath the hospital to find more vaccines, while Tyrell tries to contact whoever he can to prevent the missile strike. Jill awakens on the day of the missile strike, October 1, and pursues Carlos to the lab. Tyrell then informs her that the U.S. government will not launch the missiles if they can retrieve a vaccine from the lab within a few hours. Although Nemesis kills Tyrell shortly afterwards, Jill manages to synthesize a vaccine. She also learns that Nicholai is a supervisor hired by an unknown contractor to sabotage Umbrella's efforts to hide their involvement while collecting combat data on the company's bioweapons, including Nemesis. An encounter with Nemesis prompts Nicholai to retrieve the vaccine from Jill as he leaves her to fight the monster. Jill eliminates Nemesis with a railgun and then meets up with Nicholai at a helipad. Nicholai destroys the vaccine, acknowledging that the city's fate is not important as long as he gets paid for sabotaging Umbrella. Carlos intervenes and