DDF may refer to: Biology and medicine Digestive Disorders Foundation, a British medical research charity (N,N-dimethyl-amino)-benzenediazonium-fluoroborate, a photoaffinity probe that competes with acetylcholine for receptor binding Sulfoxone, an anti-leprosy drug sold under “DDF” brand Technology Digital distribution frame, a device which terminates digital data streams, allowing arbitrary interconnections to be made 4,4'-Dinitro-3,3'-diazenofuroxan, an experimental high explosive Disk Data Format, a structure describing how data is formatted across disks in a RAID group Other uses Demographic Development Fund, Georgian think thank Drop Dead Fred, a 1991 fantasy comedy film Dubai Duty Free, a duty-free retailer