In her first tournament after the US Open, she won her first title in the Luxembourg Open, ousting Francesca Schiavone 6–3, 6–2 in the final. She was the second lowest-ranked player ever to win a Tier-II title, being ranked No. 62, the record is held by Kim Jones-Schaefer who was ranked No. 64. She also made it through the top 50 after her first title. She then failed to qualify in the Kremlin Cup and the Zurich Open and ended the year ranked No. 32. 2007 Bondarenko started with a second-round loss to Alicia Molik at the Hobart International, 3–6, 5–7. At the Australian Open she made a valiant effort, beating two unseeded players to advance to the third round, losing to fourth seed Kim Clijsters. She then lost in the first round of the Qatar Total Open, third round of Indian Wells and second round of the Miami Masters. She also reached the third round at Amelia Island, losing to Jelena Janković. On 7 May 2007 she finished runner-up to Justine Henin at the Tier II J&S Cup held in Warsaw, losing 1–6, 3–6. In the semifinals, she got the first top-ten win of her career over then No. 5 Svetlana Kuznetsova, in straight sets. The performance saw her rise into the top 30 for the first time, at No. 29. She then followed it up with third-round appearances at German Open and Italian Open, losing to Serbians Ivanovic (retiring at 3–6, 0–5 down) and Janković respectively, which both of them eventually captured the title. She followed it by making the semifinals of the İstanbul Cup, losing to Dementieva 6–7, 2–6, once again, and this was the fourth time in a row that she has lost to the eventual champion. Despite this good performances she lost to the unseeded and lower-ranked Karin Knapp of Italy in three sets. She however bounced back with good showings at the grass season, reaching the quarterfinals of both the DFS Classic and Rosmalen Open, losing both to Janković; this was her fourth loss to her in that year. She then hit her career high shortly after Wimbledon, where she made the third round before losing to Patty Schnyder 4–6, 6–3, 6–8 after holding a 4–1 lead in the final set. She then came out with a three straight loss in the second round of the Acura Classic, first rounds of East West Bank