Lieutenant of Ireland in the ministry of Earl Grey, with Richard Wellesley, 1st Marquess Wellesley, Littleton's father-in-law, as Lord Lieutenant. The appointments met with the approval of Daniel O'Connell. However, Littleton was part of a shaky coalition of Whigs and Radicals. The Whigs were much more concerned with defending property rights and the position of the established church than the Radicals, who were prepared to sacrifice both if they perceived injustice. He was often forced to take positions which might normally have gone against his political instincts, and he also allowed his loose tongue to get him into further trouble. The main point of conflict was the issue of Irish Tithes. Incensed by the legal requirement to pay tithes to the Protestant Church of Ireland, the Repealers had launched a campaign of refusal to pay among the mainly Catholic (otherwise Presbyterian) peasantry. This sporadically flared into violence in the Tithe War. Littleton was compelled by the alliance with Whigs to bring in a Tithe Arrears (Ireland) Bill, which set out some concessions in the payment terms but reaffirmed the government's determination to impose tithes on Ireland for the foreseeable future. It was accompanied by one of the many Irish Coercion bills which partially suspended civil rights in Ireland to suppress rural violence. Initially, Littleton seemed to be steering a compromise course fairly successfully. On the one hand he portrayed the recovery of tithes as a painful necessity, while denouncing unwarranted and sometimes illegal police violence. However, this could not last. As early as 10 July, Littleton upset the Irish Repealers in the Commons. Feargus O'Connor, one of the most radical of the Irish party, brought forward a petition demanding the repeal of the Acts of Union 1800. Littleton responded that: "That was a proposition so utterly devoid of commonsense, that it was scarcely necessary for him to say, that when it was brought forward, it would be met by the most strenuous opposition. He need scarcely use such strong language, for the proposition was so extremely absurd — so opposed to the feelings and interests of both Englishmen and Irishmen, that any strenuous exertion would be totally unnecessary, in order to ensure it a signal defeat." This was clearly far beyond what was necessary to dissociate himself from O'Connor. However, there was no real chance of repeal going through at that point. Rather hastily he made a compact with O'Connell