(stress response pathway activation) may be the development of dental fluorosis after childhood exposure (between the ages of 2 to 8 years old) to excess consumption of fluoride, an elemental agent used to increase enamel hardness and as a result, prevent dental caries. See also Ameloblastin Ameloblastoma Amelogenesis imperfecta Dentin Enamel Odontoblast Tooth development List of human cell types derived from the germ layers References External links Non-terminally differentiated (blast) cells Animal cells Human cells