at the former site of the House of the Virgins of the Sun. During the Siege of Cuzco of 1536 by Manco Inca Yupanqui, a leader of the Sapa Inca, he took control of the city from the Spanish. Although the siege lasted 10 months, it was ultimately unsuccessful. Manco's forces were able to reclaim the city for only a few days. He eventually retreated to Vilcabamba, the capital of the newly established small Neo-Inca State. There his state survived another 36 years but he was never able to return to Cuzco. Throughout the conflict and years of the Spanish colonization of the Americas, many Incas died of smallpox epidemics, as they had no acquired immunity to a disease by then endemic among Europeans. Cusco was built on layers of cultures. The Tawantinsuyu (former Inca Empire) was built on Killke structures. The Spanish replaced indigenous temples with Catholic churches, and Inca palaces with mansions for the invaders. Cusco was the center for the Spanish colonization and spread of Christianity in the Andean world. It became very prosperous thanks to agriculture, cattle raising and mining, as well as its trade with Spain. The Spanish colonists constructed many churches and convents, as well as a cathedral, university and archdiocese. Present A major earthquake on 21 May hit in 1950, and caused damage in more than one third of the city's structures. The Dominican Priory and Church of Santo Domingo, which were built on top of the impressive Qurikancha (Temple of the Sun), were among the affected colonial era buildings. Inca architecture withstood the earthquake. Many of the old Inca walls were at first thought to have been lost after the earthquake, but the granite retaining walls of the Qurikancha were exposed, as well as those of other ancient structures throughout the city. Restoration work at the Santo Domingo complex exposed the Inca masonry formerly obscured by the superstructure without compromising the integrity of the colonial heritage. Many of the buildings damaged in 1950 had been impacted by an earthquake only nine years previously. Since the 1990s, tourism has increased. Currently, Cusco is the most important tourist destination in Peru. Under the administration of mayor Daniel Estrada Pérez, a staunch supporter of the Academia Mayor de la Lengua Quechua, between 1983 and 1995 the Quechua name Qosqo was officially adopted for the city. Honors In 1933, the Congress of Americanists met in La