spread to Pentapolis from Egypt; Synesius of Cyrene (370–414), bishop of Ptolemais, received his instruction at Alexandria in both the Catechetical School and the Museion, and he entertained a great deal of reverence and affection for Hypatia, the last pagan Neoplatonist, whose classes he had attended. Synesius was raised to the episcopate by Theophilus, patriarch of Alexandria, in AD 410. Since the First Council of Nicaea in AD 325, Cyrenaica had been recognized as an ecclesiastical province of the See of Alexandria, in accordance with the ruling of the Nicaean Fathers.The patriarch of the Coptic Church to this day includes the Pentapolis in his title as an area within his jurisdiction. The Eparchy of the Western Pentapolis was part of the Coptic Orthodox Church of Alexandria, as the Pope of Alexandria was the Pope of Africa. The most senior position in The Holy Synod of the Coptic Orthodox Church after the Pope was the Metropolitan of Western Pentapolis, although, since its demise as a major Archiepiscopal Metropolis in the days of Pope John VI of Alexandria, it was held as a Titular See attached to another Diocese. After being repeatedly destroyed and restored during the Roman period Pentapolis became a mere borough, but was nevertheless the site of a diocese. Its bishop, Zopyrus, was present at the First Council of Nicaea in 325. The subscriptions at Ephesus (431) and Chalcedon (451) give the names of two other bishops, Zenobius and Theodorus. Although it retained the title "Pentapolis", the ecclesiastic province actually included all of the Cyrenaica, not just the five cities. Pentapolis is still included in the title of Popes of the Coptic Orthodox Church and the Greek Orthodox Church of Alexandria. Arab and Ottoman rule Cyrenaica was conquered by Muslim Arabs under command of Amr ibn al-As during the tenure of the second caliph, Omar, in , and became known as Barqah after its provincial capital, the ancient city of Barce. After the breakdown of the Ummayad caliphate it was essentially annexed to Egypt, although still under the same name, first under the Fatimid caliphs. In the middle of the 11th century, the Bedouin Banu Hilal confederation devastated the North African coast under Muslim control. Barqa was ravaged by the Hilalian invasion and left to be settled by the Banu Sulaym while the Banu Hilal marched westwards. The invasion contributed to the decline of the port cities and maritime