a half-life of at least 100 years. Every known isotope of the remaining 25 elements is highly radioactive; these are used in academic research and sometimes in industry and medicine. Some of the heavier elements in the periodic table may be revealed to have yet-undiscovered isotopes with longer lifetimes than those listed here. About 338 nuclides are found naturally on Earth. These comprise 251 stable isotopes, and with the addition of the 35 long-lived radioisotopes with half-lives longer than 100 million years, a total of 286 primordial nuclides, as noted above. The nuclides found naturally comprise not only the 286 primordials, but also include about 52 more short-lived isotopes (defined by a half-life less than 100 million years, too short to have survived from the formation of the Earth) that are daughters of primordial isotopes (such as radium from uranium); or else are made by energetic natural processes, such as carbon-14 made from atmospheric nitrogen by bombardment from cosmic rays. Elements by number of primordial isotopes An even number of protons or neutrons is more stable (higher binding energy) because of pairing effects, so even–even nuclides are much more stable than odd–odd. One effect is that there are few stable odd–odd nuclides: in fact only five are stable, with another four having half-lives longer than a billion years. Another effect is to prevent beta decay of many even–even nuclides into another even–even nuclide of the same mass number but lower energy, because decay proceeding one step at a time would have to pass through an odd–odd nuclide of higher energy. (Double beta decay directly from even–even to even–even, skipping over an odd-odd nuclide, is only occasionally possible, and is a process so strongly hindered that it has a half-life greater than a billion times the age of the universe.) This makes for a larger number of stable even–even nuclides, up to three for some mass numbers, and up to seven for some atomic (proton) numbers and at least four for all stable even-Z elements beyond iron (except strontium and lead). Since a nucleus with an odd number of protons is relatively less stable, odd-numbered elements tend to have fewer stable isotopes. Of the 26 "monoisotopic" elements that have only a single stable isotope, all but one have an odd atomic number—the single exception being beryllium. In addition, no odd-numbered element has more than two stable isotopes, while every even-numbered element