at that point. Since the announcement by Sanofi, at least 62 children have died, allegedly after receiving a vaccination. The victims' parents blamed the dengue vaccine for the deaths of their children. In July 2020, Sanofi Pasteur announced that it would begin phase three testing of a COVID-19 vaccine in several countries, including Mexico, and that the cost would be US $7 to $10 per dose. If data are positive, a global phase 3 study could start in Q2 2021. If the vaccine meets clinical requirements on safety and effectiveness, approved by regulatory authorities, a vaccine can expected in the fourth quarter of 2021. One of the vaccines ordered by the Netherlands for the mass anti-coronavirus vaccination programme in 2021 seems not to work well in elderly people and the development of the vaccine will face delays. In 2021, Sanofi Toronto announced it was seeking to start a new Biosafety level 3 laboratory. Key dates 1897: Marcel Mérieux creates the Mérieux Biological Institute in Lyon. Richard Slee creates the Pocono Biological Laboratories, in Swiftwater, Pennsylvania in the U.S. 1914: John G. FitzGerald creates Connaught Laboratories, part of the University of Toronto. 1968: Rhône-Poulenc acquires 51% of the capital of the Institut Mérieux. 1974: Pasteur Institute creates Pasteur Production, a subsidiary specializing in manufacturing vaccines. 1978: Connaught Laboratories in Canada acquires the vaccine manufacturing facility (Merrell-National Laboratories) at Swiftwater, Pennsylvania, U.S. 1985: Pasteur Production is acquired by the Mérieux Institute, and Pasteur Vaccins is created. 1989: The Mérieux Institute acquires the Connaught Laboratories in Canada and its subsidiaries and becomes a world leader in human biology. 1990: Creation of Pasteur Mérieux Serums & Vaccins. 1994: Pasteur Mérieux Sérums & Vaccins becomes a wholly owned subsidiary of Rhône-Poulenc. 1996: Pasteur Mérieux Connaught is the new name of Pasteur Mérieux Serums et Vaccins. 1999: Rhône-Poulenc and Hoechst unite their Life Sciences activities in a single company, which takes on the name Aventis. Within this group, Pasteur Mérieux Connaught changes its name to Aventis Pasteur. 2004: merger of Aventis with and into Sanofi. The new Sanofi-Aventis Group becomes the world's 3rd largest pharmaceutical company, behind Pfizer and GlaxoSmithKline. Aventis Pasteur, the vaccine division of the Sanofi-Aventis Group, changes its name to Sanofi Pasteur. 2008: Sanofi Pasteur acquires Acambis plc, a biotech company. 2009: Sanofi Pasteur acquires major stake in Hyderabad-based Shantha Biotechnics. 2020: Sanofi Pasteur and GlaxoSmithKline have said they are starting clinical trials