Bastad and Portoroz. Her bad form continued when she lost three straight first-round matches during the US Open Series. She fell in the first round of the US Open to qualifier Chang Kai-chen in three sets. Kanepi lost to Chang again in the first round at Tokyo. She suffered a first-round loss at the China Open in Beijing to Serena Williams in a match where she had more break points than Serena and lost 5–7, 4–6. This was her 12th straight loss. Kanepi ended her losing streak at an ITF tournament Dubai in December, where she defeated Yuliana Fedak in straight sets in the first round. She then lost to Regina Kulikova. 2010: Wimbledon and US Open quarterfinals By the start of the new season, Kanepi seemed to be in better physical shape than in 2009. Kanepi reached the second round at the Auckland Open, defeating world No. 15, Li Na, in straight sets, before losing to Maria Kirilenko in the second round. She fell in the first round of the Hobart International to seventh seed Zheng Jie in a tight three-setter. At the first Grand Slam of the year at the Australian Open, Kanepi defeated Chan Yung-jan in the first round, but fell to 19th seed Nadia Petrova in the second round. Kanepi was seeded fifth at the Cellular South Cup in Memphis. She was in the same half of the draw as Maria Sharapova. She defeated Arantxa Rus in the first round, and former world No. 7, Nicole Vaidišová, in the second round. She fell in three sets to fifth seed Petra Kvitová in the quarterfinals. Despite this, Kanepi's ranking fell to world No. 96, due to the fact that she did not defend her points from Dubai from the previous year. Kanepi reached the second round in Acapulco, but lost to top seed and defending champion Venus Williams. Kanepi also fell in the second round of the Monterrey Open to second seed Daniela Hantuchová in straight sets. Kanepi then competed in two Premier Mandatory tournaments. At the Indian Wells Open and the Miami Open, she fell in the first rounds to Sorana Cîrstea and Lucie Šafářová respectively. Kanepi's ranking fell out of the top 100 following these tournaments. She then represented Estonia in the 2010 Fed Cup World Group Play-offs against Belgium. She was defeated by world No. 12 Yanina Wickmayer in her first match, but defeated