Schiavone, Yanina Wickmayer and Naomi Osaka, reaching the second week at a major since the 2014 US Open. She then defeated Daria Kasatkina to advance to her second US Open quarterfinal, her sixth Grand Slam quarterfinal overall, and her first quarterfinal at a major since Wimbledon 2013. She lost her quarterfinal match to 15th seed and eventual finalist, Madison Keys. Nonetheless, she made history by becoming only the second qualifier in US Open history to make the quarterfinals and the first to do so since Barbara Gerken in 1981. Following the US Open, Kanepi's ranking skyrocketed from 418 to 110. Getting past qualifying at the Kremlin Cup, Kanepi was defeated in the first round by Natalia Vikhlyantseva. As the top seed at the Open Nantes Atlantique, Kanepi won the tournament defeating Richèl Hogenkamp in the final. Kanepi played her final tournament of the year at the Open de Limoges. Seeded seventh, she lost in her quarterfinal match to third seed Pauline Parmentier. Kanepi managed to finish the year ranked at 107, her best end-of-year ranking since 2014. 2018 Kanepi began season at the Brisbane International. Qualifying for the main draw, she reached the quarterfinal round beating Daria Kasatkina and Lesia Tsurenko. She lost her quarterfinal match to second seed and defending champion Karolína Plíšková. This helped propel her back into the top 100 for the first time since August 2015. At the Australian Open, Kanepi upset 24th seed Dominika Cibulková in the opening round. She then defeated Monica Puig in the second round to advance to the third round of the Australian Open for the first time since 2009. Her run ended as she was defeated in the third round by Carla Suárez Navarro. In March, Kanepi competed at Indian Wells; she lost in the second round to 17th seed CoCo Vandeweghe. She then retired during her first-round match at Miami against Christina McHale. Kanepi began her clay-court season at the Porsche Tennis Grand Prix. She lost in the final round of qualifying to Zarina Diyas. Even though she qualified for the Italian Open, Kanepi was defeated in the second round by ninth seed Sloane Stephens. Coming through the qualifying round at Strasbourg, Kanepi lost in the first round to eighth seed Hsieh Su-wei. At the French Open, Kanepi was defeated in the first round by 14th seed Daria Kasatkina. Despite the loss, she returned to the top 50 of