By the time of the Second Punic War (218–201 BC), they also controlled areas as far south as the coastal mountains near Massalia. Conflicts between Rome and the Salyes lasted during nearly eighty years from the end of the Second Punic War (201 BC), during which the eastern part of Iberia came under Roman control and Massalia remained a faithful ally of Rome, up until the rendition of the Salluvian chief town Entremont ca. 122 BC. Involved in piracy and raids, the Ligurians threatened throughout the 2nd century BC the Massaliotes colonies along the Mediterranean coast, and more generally the trade route between the Iberian Peninsula and Italy. This culminated in a Roman military intervention in 154 BC against the Deciates and Oxybii, two Ligurian tribes that were presumably part of the Salluvian confederation. Roman conquest In 125 BC, the Salyes waged war on Massalia, leading the Roman Senate to send the consul Marcus Fulvius Flaccus to Massalia's assistance. The establishment of a Greek colony at Glanum, on Salluvian territory, may have been the casus belli. Flaccus defeated the Salyes, along with the Vocontii and some other Ligurian tribes presumably part of the Salluvian confederation on the eastern borders of the Massaliote territory, then celebrated his triumph in Rome in 123 BC. Shortly after, another consul, Gaius Sextius Calvinus, sacked their chief town, Entremont, and established near its ruin a Roman garrison post, thereafter to be known as Aquae Sextiae (modern Aix-en-Provence). Sextius also forced the Salyes to cede the areas they controlled near the Mediterranean coast; part of their territory was granted to the Massaliotes. During the conflict, the leaders of the Salyes, including their king Toutomotulos (or Teutomalius), fled with the rest of their armies to their allies the Allobroges, who refused to hand them over to Rome. A further and larger Roman force, including war elephants, was sent under the command of Gnaeus Domitius Ahenobarbus, who defeated the Allobroges at the Battle of Vindalium in 121 BC. In August of the same year, the Roman army, strengthened by the troops of Quintus Fabius Maximus, inflicted a decisive defeat on a massive combined force of Allobroges, Arveni and the remaining Salyes at the Battle of the Isère River. Toutomotulus' followers were killed, enslaved, or driven into exile, while Crato, the Salluvian leader of the pro-Graeco-Roman faction, was granted 900 of his fellow citizens from slavery. Between 120 and