marine organisms which allowed for more research into their biological roles. Prostaglandins were discovered to be products of arachidonic acid and with the ability to radio label arachidonic acid in the early 1960s, American chemist E.J. Corey was able to synthesize prostaglandin E2 in the lab in the 1970. This advancement paved the way for later studies that helped define the actions and response of prostaglandin E2. Prostaglandin E2 was approved for medical use in the United States in 1977 and it is on the World Health Organization's List of Essential Medicines. Prostaglandin E2 was approved by the FDA in 1977. References External links Abortifacients Alkene derivatives Aromatase inhibitors AbbVie brands Carboxylic acids Cyclopentanes Ketones Obstetric drugs Prostaglandins Secondary alcohols World Health Organization essential medicines Wikipedia medicine articles ready to translate