identified, their respective roles in CVID development are poorly understood, and not represented in all people with CVID. Finding new ways to study CVID. Given that CVID arises from more than one gene, gene knock-out methods are unlikely to be helpful. It is necessary to seek out disease related polymorphisms by screening large populations of people with CVID, but this is challenging given the rarity of the disease. References (IVIG and Aseptic Meningitis, association with SLE) External links GeneReviews/NCBI/NIH/UW entry on Common Variable Immune Deficiency Overview Genetic diseases and disorders Noninfectious immunodeficiency-related cutaneous conditions Predominantly antibody deficiencies