opera Another World, and New York Undercover. In 1998, he was cast as series regular in the short-lived CBS primetime soap opera Four Corners. Chambers has also appeared in several television movies, such as Harvest of Fire, Rose Hill, and Seasons of Love. Chambers starred in several movies, notably Liberty Heights (1999, as Trey, alongside Adrien Brody), The Wedding Planner (2001, as Massimo, alongside Jennifer Lopez), The Musketeer (2001), Southern Belles (2005), The Zodiac (2005), and the HBO original movie Hysterical Blindness (2002). In 2003, Chambers was cast as one of the leads in the CBS crime drama Cold Case but left after appearing in only three of the show's first four episodes. In August 2004, Chambers was cast as surgical intern Alex Karev in Shonda Rhimes's medical drama series Grey's Anatomy, opposite Ellen Pompeo, Sandra Oh, Katherine Heigl, and T. R. Knight. In 2006, along with other cast members, he was awarded a Screen Actors Guild Award for Outstanding Performance by an Ensemble in a Drama Series. In 2009, he also guest-starred on the Grey's Anatomy spin-off, Private Practice, for the Grey's Anatomy/Private Practice crossover event. On January 10, 2020, Chambers officially announced his departure from Grey's Anatomy and that his final episode had aired on November 14, 2019, with a farewell episode airing on March 5, 2020. Personal life In 1993, he married Keisha Chambers, a former model agency booker. The two met while Chambers was working for ad campaigns for Calvin Klein and Keisha was working at a modeling agency. They have five children: Isabella (b. December 1994), twins Maya and Kaila (b. June 1997), Eva (b. March 1999) and Jackson (b. January 2002). They have adopted two rescue dogs and own a beagle. Chambers is involved with the nonprofit organization Pentecostal Christian Church mission Dream Center of Los Angeles. In late January 2008, he revealed that he suffered from a sleep disorder and had checked himself into UCLA Medical Center to treat exhaustion after a period of only two hours of sleep each week. Chambers practices hot yoga. Filmography Film Television Awards and nominations References External links 1970 births Living people Male actors from Ohio American male film actors American male television actors American male voice actors People from Springfield, Ohio 20th-century American male actors 21st-century American male actors American twins