the director is furious at Kaori and the children's escape, and has her security guard Kimiko and the two artificial nurses pursue them on the surface, much to their chagrin. After several years of living on the surface, Kaori's health deteriorates as she cannot stomach real food, only Pure Trance, whereas the children thrive and grow into adults. While the children are out tripping on hallucinogenic mushrooms one day, Kimiko and the nurses encounter Seiko, who unwittingly leads them to Kaori, whom they capture and take back to the director. When the children return home, the twins use their powers to locate Kaori, but unfortunately witness the director poisoning her to death. The incident leaves them very weak and their hair turns white. Meanwhile, a hole develops in the dilapidated dome covering Tokyo, and plants and animals from the surface begin creeping into the underground. A research team is formed by Professor Kajiwara to explore and determine the habitability of the surface. The children, saddened by Kaori's death and frightened by the explorers, hide in the ruins of a love motel. The director however has a nightmare about the children and a mysterious dark haired woman, and upon waking forces Kimiko and the artificial nurses to venture once more to the surface, this time to kill the children. Rika, who is popular among the brain creatures of the surface, gets pregnant from one of her boyfriends, while the twins have a vision that they will die soon and Rika will die in childbirth. They suggest combining their powers with Yuriko, and perform a ritual that transfers their souls into her body. Rika gives birth to a daughter, Yuka, but dies in the process and becomes one of the brain creatures. At Center 102, a patient spots a bird that flies in through the window and eats it, causing her to recover from her overeating illness quickly. The few remaining human nurses utilize this information to create a cheap and effective cure for overeating, causing the center to be shut down and the director to be arrested. They then open a successful pachinko parlor in the building. With the director gone, Kimiko becomes a female wrestling star while the artificial nurses are taken in at a nurse themed hostess bar. Deconstruction of the dome over Tokyo begins and real food as well as the integration of the brain creatures and the