Cayuse may refer to: Cayuse people, a people native to Oregon, United States Cayuse language, an extinct language of the Cayuse people Cayuse, Oregon, an unincorporated community in the United States Cayuse horse, an archaic term for a feral or low-quality horse or pony OH-6 "Cayuse", a military observation helicopter Cayuse Five, five Cayuse who were hanged for murder See also Cayoosh Flat is also the old name for the town of Lillooet, British Columbia