Aumale, François de Lorraine, Grand Prior and René, Marquis of Elbeuf were born in 1519, 1524, 1526, 1534 and 1536 respectively. Meanwhile his sister Marie de Guise, mother of Mary, Queen of Scots was born in 1515. To avoid a fracturing of the families inheritance, Louis was destined for a career in the church. Ecclesiastic empire While Cardinal Guise could not claim the same number of benefices as his older brother, he was not without many abbeys, and together they formed a large ecclesiastical empire. Guise for his part controlled the abbey of Notre Dame des Trois Fontaines, Saint-Pierre and Saint-Thierri in Champagne alone. With his elevation to Cardinal in 1553, the family could boast of having two Cardinals in the same generation. To maintain the families ecclesiastical empire more effectively, they engaged in benefice juggling. Cardinal Guise bequeathed several abbeys in commendam to his nephew Claude, Chevalier d'Aumale. In total these provided revenues of 40,000 livres to the young chevalier. Just one of these abbey's, which Guise resigned in 1572, that of Bec, had annual revenues of 24,000 livres which was twice the revenues provided by his brothers' duchy of Aumale. Upon Cardinal Guise's death in 1578, the chevalier acquired many more of his abbeys. Cardinal des bouteilles Cardinal Guise acquired in his lifetime the derisive moniker of 'cardinal des bouteilles' due to his reputed fondness for drinking. He acquired great wealth during his lifetime, and was the longest living of all the Guise brothers of his generation. However he lacked the capacity or inclination to be a leader in the way his brothers Lorraine and Guise had been in the previous decade. His nephew was Louis II, Cardinal of Guise (made cardinal, 1578). His great-nephew was Louis III, Cardinal of Guise (made cardinal, 1615). Reign of Henri II Troyes and Albi Guise was made Bishop of Troyes on 11 May 1545, at the age of 18, a position he had to hold as administrator until he reached the canonical age of 27. Upon the death of François I in 1547, Cardinal Guise had reached an age at which he could participate actively in court life. During 1550 in his capacity as bishop of Troyes, he had been sent 5 suspects who had been accused of blasphemy and heresy. They had originally been sent to the Parlement of Paris for trial, but the Parlement simply sent them back for