triennial prize of 300 guineas for his essay on "The Coagulation of the Blood." Epilogue Richardson died at 25 Manchester Square on 21 November 1896, and his body was cremated at Brookwood, Surrey. Richardson was a sanitary reformer, who busied himself with many of the smaller details of domestic sanitation which tend, in the aggregate, to prolong the average life in each generation. He spent many years in attempts to relieve pain among men by discovering and adapting substances capable of producing general or local anaesthesia, and among animals by more humane methods of slaughter. He brought into use, no less than fourteen anaesthetics, of which methylene bichloride is the best known, and he invented the first double-valved mouthpiece for use in the administration of chloroform. He also produced local insensibility by freezing the part with an ether spray, and he gave animals euthanasia by means of a lethal chamber. Richardson was an ardent and determined champion of total abstinence, for he held that alcohol was so powerful a drug that it should only be used by skilled hands in the greatest emergencies. He was also one of the earliest advocates of bicycling; he wrote 'Cycling as an Intellectual Pursuit' for Longman's Magazine in 1883. In 1863, he made known the peculiar properties of amyl nitrite, a drug which was largely used in the treatment of breast-pang (angina pectoris), and he introduced the bromides of quinine, iron and strychnia, ozonized ether, styptic and iodized colloid, peroxide of hydrogen, and ethylate of soda, substances which were soon largely used by the medical profession. Richardson was a vice-president of the Bread Reform League. The League formed in 1880 to spread "knowledge of the dietetic advantage of Wheat-Meal Bread." Richardson opposed the slaughter of animals but was not a vegetarian. He wrote that "It is quite true that I lean strongly towards the vegetarian movement. I have not, however, become a strict vegetarian, but have rather busied myself in showing how animals can be painlessly killed and carefully cleansed for the meat-market." Richardson was one of the most prolific writers of his generation. He wrote biographies, plays, poems, and songs, in addition to his more strictly scientific work. He wrote the Asclepiad, a series of original researches in the science, art, and literature of medicine. A single volume was issued in 1861, after which it appeared quarterly from 1884 to 1895. He was