136 Bill Doak | 131 Bill Sherdel | 127 Bob Forsch |- | Winning percentage | .719 Ice Box Chamberlain64 dec. | .718 Ted Wilks71 dec. | .705 John Tudor88 dec. | .704 Dave Foutz162 dec. | .700 Silver King (160 dec.),Tony Mullane (50 dec.) |- | Games played | 554 Jesse Haines | 528 Bob Gibson | 465 Bill Sherdel | 457 Adam Wainwright | 455 Bob Forsch |- | Games started | 482 Bob Gibson | 401 Bob Forsch | 390 Adam Wainwright | 387 Jesse Haines | 320 Bill Doak |- | Innings pitched | 3,884.1 Bob Gibson | 3,203.2 Jesse Haines | 2,658.2 Bob Forsch | 2,567.1 Adam Wainwright | 2,450.2 Bill Sherdel |- | Complete games | 255 Bob Gibson | 209 Jesse Haines | 198 Ted Breitenstein | 156 Dave Foutz | 154 Silver King |- | Shutouts | 56 Bob Gibson | 30 Bill Doak | 28 Mort Cooper | 25 Harry Brecheen | 23 Dizzy Dean, Jesse Haines |- | Saves | 217 Jason Isringhausen | 160 Lee Smith | 129 Todd Worrell | 127 Bruce Sutter | 121 Trevor Rosenthal |- | Games finished | 332 Jason Isringhausen | 232 Todd Worrell | 209 Lee Smith | 203 Bruce Sutter | 188 Lindy McDaniel |- | Hits allowed | 3,455 Jesse Haines | 3,279 Bob Gibson | 2,721 Bill Sherdel | 2,602 Bob Forsch | 2,426 Adam Wainwright |- | Earned runs allowed | 1,297 Jesse Haines | 1,258 Bob Gibson | 1,085 Bob Forsch | 992 Bill Sherdel | 964 Adam Wainwright |- | Strikeouts | 3,117 Bob Gibson | 2,147 Adam Wainwright | 1,095 Dizzy Dean | 1,085 Chris Carpenter | 1,079 Bob Forsch |- | Bases on balls allowed | 1,336 Bob Gibson | 870 Jesse Haines | 843 Ted Breitenstein | 780 Bob Forsch | 740 Bill Doak |- | Home runs allowed | 257 Bob Gibson | 213 Adam Wainwright | 204 Bob Forsch | 165 Jesse Haines | 152 Larry Jackson |- | Hit batsmen | 102 Bob Gibson | 80 Adam Wainwright | 72 Willie Sudhoff | 68 Silver King | 59 Carlos Martínez |- | Wild pitches | 111 Jumbo McGinnis | 108 Bob Gibson | 88 Bob Forsch | 78 Silver King | 77 Dave Foutz |- | Batters faced | 16,068 Bob Gibson | 13,624 Jesse Haines | 11,088 Bob Forsch