the years. By 2001, director Sidney Lumet cast her in 100 Centre Street playing three different roles (Ellen, Paris and Rebecca). Ryan went on to feature prominently in the second season of HBO's The Wire, playing Port Authority Officer Beadie Russell. She appeared for a six-episode arc on The Office as dorky HR rep Holly Flax. She reprised her role on The Office in seasons 5 and 7. Ryan joined the cast of HBO's In Treatment for its third season, playing the therapist of Dr. Paul Weston. Film Because of the deletion of the scene where she played Eric Stoltz's wife in Allison Anders's Grace of My Heart, Ryan made her 1999 film debut in Roberta. She then briefly appeared in You Can Count on Me, which starred Laura Linney and Mark Ruffalo, and the mystery/thriller Keane. Albert Brooks chose her to play his wife in Looking for Comedy in the Muslim World in 2005, and 2007 brought both Dan in Real Life and Before the Devil Knows You're Dead. Her role as a star-struck sheriff's wife in Capote earned her positive reviews, but it was playing a hardened welfare mom in Ben Affleck's Gone Baby Gone that finally brought her national attention. After being voted Best Supporting Actress for Gone Baby Gone by the National Board of Review, as well as the critics circles in New York, Los Angeles, Boston, San Francisco and Washington, D.C., Ryan's performance was also nominated for a Golden Globe Award, a Screen Actors Guild Award, and an Oscar for Best Performance by an Actress in a Supporting role at the 80th Academy Awards. Ryan appeared in Changeling (2008), directed by Clint Eastwood, and opposite Matt Damon in Paul Greengrass's Green Zone (2010). In September 2010, she completed filming a role in Philip Seymour Hoffman's directorial film debut, Jack Goes Boating, taking over the role of Connie originally played by Beth Cole in the stage version. Ryan received strong notices for her performance in Tom McCarthy's Win Win the next year, winning Best Supporting Actress awards from multiple regional critics groups. Ryan was a part of the core ensemble of the 2014 Best Picture Academy Award winning film Birdman, sharing in the cast's Screen Actors Guild Award for Outstanding Performance by a Cast in a Motion Picture victory. In 2015, she starred as Mary Donovan opposite Tom Hanks in the film Bridge of Spies, and