especially in view of the Royal Proclamation of 1763 (which prohibited settlement west of the Appalachian Mountains), and was a foundation of one of the major irritants for the colonials leading up to the American Revolution. See also Cherokee–American wars Sycamore Shoals References Sources See ch. 47, "The Cherokee War and Amherst's Reforms in Indian Policy", pp. 457–71. Also Dover, 1995. Colonial American and Indian wars Conflicts in 1758 Conflicts in 1759 Conflicts in 1760 Conflicts in 1761 French and Indian War 18th century Cherokee history Pre-statehood history of South Carolina Pre-statehood history of Tennessee Wars involving Great Britain Wars involving the indigenous peoples of North America