manifestations of the disease, and more especially when these manifestations have been of a serious nature, one or more of the offspring almost invariably suffer from the disease, if they live to adult age” Those who suffered from it showed suicidal tendencies and dementia: “mind and body both gradually fail until death relieves them of their sufferings” The illness manifested itself in adulthood and worsened with age: “these movements gradually increase, when muscles hitherto unaffected take on the spasmodic action, until every muscle in the body becomes affected” A summary was published in the German literature of Adolf Kussmaul and Carl Wilhelm Hermann Nothnagel in 1872 and, subsequently, the eponym was used more often by European authors. Huntington recognized the hereditary characteristic of the disease, stating in his original document: “when either or both of the parents have shown manifestations of the disease…one or more of the offspring almost invariably suffer from the disease…it never skips a generation to again manifest itself in another; once having yielded its claims, it never regains them.” In a 1908 review article, the eminent physician William Osler said of this paper: "In the history of medicine, there are few instances in which a disease has been more accurately, more graphically or more briefly described." Currently there is a tendency to use the term Huntington’s disease rather than Huntington’s chorea, but the original title is still very well-known, accepted, and understood. Jelliffe and Tilney were given the task of tracing the ancestry of affected families, a study that was finished some years later by Vessie (1932). They found that it came from two brothers and their families who had left Bures (in Essex) from Suffolk, England, and later sailed to the Boston Bay in 1630. Over the course of those three centuries, close to 1,000 descendants of the original colonists are known to have arrived with the disease. More than a few of these unlucky people were tried for witchcraft in colonial courts, and also in other ways, were persecuted because their involuntary movements were interpreted as “a derisive pantomime of the sufferings of the Savior during crucifixion.” Progressive and hereditary chorea had been described before 1872. The most complete clinical description, even including the dementia component, was published as early as 1859 by Johan Christian Lind, the doctor from the Setesdal district in Norway. This paper did not get international attention and was certainly