the Church of the Gesù in Rome, the Villa Farnese at Caprarola, and the Farnese palace near Lake Bracciano, and the monastery Tre Fontane. Alessandro Farnese is remembered for gathering the greatest collection of Roman sculpture assembled in private hands since Antiquity, now mostly in Naples, after passing by inheritance to the Bourbon-Parma kings. His generosity towards artists made a virtual academy at the house he built at Caprarola, and in his lodgings at Palazzo della Cancellaria and, after his brother Cardinal Ranuccio Farnese died in 1565, at the Palazzo Farnese. In the Palazzo Farnese the best sculptors worked under his eye, to restore fragments of antiquities as complete sculptures, with great scholarly care. He was also a great patron of living artists including, most notably, El Greco. Under the direction of his curator and librarian, the antiquarian iconographer Fulvio Orsini, the Farnese collections were enlarged and systematized. Farnese collected ancient coins and commissioned modern medals. He had paintings by Titian, Michelangelo, and Raphael, and an important collection of drawings. He commissioned the masterpiece of Giulio Clovio, arguably the last major illuminated manuscript, the Farnese Hours, which was completed in 1546 after being nine years in the making (now the property of the Morgan Library, New York). The studiolo built to house this collection appears to be the one re-erected at the Musée de la Renaissance, Écouen. In 1550, Farnese acquired a northern portion of Palatine hill in Rome and had Roman ruins from the palace built by the Roman Emperor Tiberius (A. D. 14–37) at the northwest end filled in, and converted to a summer home and formal gardens. The Farnese Gardens became one of the first botanical gardens in Europe. From these gardens are derived the names of Acacia farnesiana and, from its floral essence, the important biochemical farnesol. Descendants Cardinal Alessandro Farnese had a daughter Clelia Farnese, with Claude de Beaune de Semblançay, dame de Châteaubrun, a lady-in-waiting and confidante of Catherine de Medicis, born in 1556. Claude de Beaune's brother Martin became Bishop of Puy (1557-1561) and her other brother, Renaud, Bishop of Mende (1571–1581) and then Archbishop of Bourges. In 1570, Clelia married Giangiorgio Cesarini, Marchese of Civitanova, Gonfaloniere of the City of Rome (1565-1585). In September 1572, they had a son, Giuliano. Clelia's husband died in 1585. On 2 August 1587, at the Farnese palace in Caprarola, she married her second husband, Marco Pio