represents a spin-off of Hood's labs at UW. Achievements ISB is in the top ranks of scientific institutions worldwide. In 2012, the SCImago Research Group, based in Spain, ranked ISB 4th worldwide on its Excellence Rate scale. ISB currently hosts 12 research groups with expertise ranging across genetics, microbial genetics, complex molecular machines, macromolecular complexes, gene regulatory networks, immunology, molecular and cell biology, cancer biology, genomics, proteomics, protein chemistry, computational biology and biotechnology. The ISB website lists 985 peer-reviewed publications for the years 2000 through early 2012. In late 2005, ISB began to emphasize the application of systems biology to P4 medicine (predictive, preventive, personalized, participatory), i.e. the development of techniques for predicting and preventing disease, possibly before patients even know they are sick. The P4 Medicine institute was co-founded in 2010 by ISB and Ohio State University. The Education and Outreach efforts of ISB include creating the Logan Center for Education whose mission is to enable educators to produce STEM literate students. ISB offers paid research internships for high school and undergraduate students, and offers advanced systems science courses throughout the year. ISB partnered in several high-profile research projects, the most significant one thus far being with the Grand Duchy of Luxembourg to create the Center for Systems Biology Luxembourg and the Seattle Proteome Center. ISB faculty members have launched several companies, including: Cytopeia (acquired by BD in 2008), Integrated Diagnostics, Macrogenics, NanoString Technologies, and Accelerator Corporation. Accelerator Corporation, in particular, is an investment company that provides venture capital funding and management for biotech startup companies. Its portfolio companies and graduates have focused on improved biotherapeutics, vaccines, biomarkers and other such products. See also List of systems sciences organizations References External links ISB website Seattle Proteome Center Bioinformatics organizations Systems biology Systems science institutes Research institutes in Seattle Research institutes established in 2000 2000 establishments in Washington (state)