Isham Randolph (February 24, 1687 – November 2, 1742) was a planter, a merchant, a public official, and a shipmaster. He was the maternal grandfather of United States President Thomas Jefferson. Early life Isham Randolph was born on the Turkey Island plantation in Henrico County, Virginia on February 24, 1687. He was the third son of William Randolph (1650–1711) and Mary Isham ( 1659–1735). His father was a colonist, landowner, planter, and merchant who served as the 26th Speaker of the Virginia House of Burgesses. Randolph graduated from the College of William & Mary. Marriage and children In 1717, Isham Randolph married Jane Rogers in London at St. Paul's Church in the Shadwell parish (today east London). Jane was from a wealthy landed gentry family of England and Scotland. Isham and Jane Randolph moved to Virginia. Together, they had nine children and were familially connected to many other prominent individuals: Jane Randolph (born 1720), who married Peter Jefferson and had nine children, including Thomas Jefferson, the third President of the United States. Mary Randolph (born October 1725 in Colonial Williamsburg), who married Colonel Charles Lewis of Buck Island and had eight children, including Charles Lilburn Lewis, one of the founders of Milton, Virginia. Isham Randolph (born ~1725), married Sarah Hargreaves in 1749, in Philadelphia. William Randolph (born ~1727), married Elizabeth Little on 31 July, 1761, in London. Thomas Randolph (born ~1728), who married Jane Cary, the daughter of Archibald Cary, in 1768. Elizabeth Randolph (born ~1730) Dorothea Randolph (born ~1732) Ann Randolph (born ~1735), who had four children in three marriages. She was the mother of James Pleasants Jr., the 22nd Governor of Virginia, via her last marriage to James Pleasants Sr. Susannah Randolph (born September 25, 1738), who married Carter Henry Harrison I (the brother of Benjamin Harrison V, the son of Benjamin Harrison IV, and the grandson of Benjamin Harrison III and Robert "King" Carter) and had six children. She was the great-grandmother of Carter Henry Harrison III, a five-time mayor of Chicago. Career and death Following his father, he was a prominent planter, merchant, public official, and also was a shipmaster. In London, Randolph was a well-established merchant and agent for the colony of Virginia. By the birth of his second daughter, Mary, in October 1725, he returned to Colonial Virginia. In 1730, he built Dungeness, with English manor house style architecture on what became a large