staining light microscopy and its electron density for electron microscopy, appears first in carbohydrates before it stains unsaturated lipids. He also demonstrated the presence of a carbohydrate-containing moiety in myelin (later shown by others to be different proteoglycans) and its importance in myelin breakdown. His research was focused on the oxidation of lipids, the formation of lipid peroxides, their polymerization, and the pathogenesis and nature of lipid pigments. In 1959, Wolman was appointed head of the Department of Pathology of the Tel Hashomer Government Hospital (later renamed as the Chaim Sheba Medical Center). He continued to study peripheral nerve demyelinization and membrane structures. Using enzyme histochemical methods, he and his coworkers were able to prove that changes in ion concentrations can induce phase changes in cell membranes. Another study dealt with the substance (or substances) called amyloid (Wolman 1971). Understanding of the chemistry involved in histological techniques enabled Moshe Wolman in the 1950s to determine that the storage disease, that was later named after him is known as lysosomal acid lipase deficiency or Wolman disease, is caused by accumulation in cells of a mixture of cholesterol and triglycerides and differed substantially from Niemann–Pick disease. (Wolman, 1989). Wolman formulated the theory and use of polarization microscopy in routine pathology and diagnostic molecular research. He was one of the first to recognize that polarized light microscopy is a powerful tool, which allows the detection of structures that otherwise be obtained only with great difficulty (Wolman, 1970). In 1964, Wolman was appointed full professor and head of the Department of Pathology at the newly founded Medical School of Tel Aviv University. In 1967, he was also appointed chair of the Department of Cell Biology and Histology. Wolman authored more than 200 publications and contributions to books. Over the years, he contributed chapters to many textbooks and served on numerous editorial boards including Histochemie. He was deeply interested in educational and ethical questions. He published a book on ethics and demagoguery and served as chairperson of the ethics committee of the Israel Medical Association. He was concerned with the issues of medical errors and published a book on the subject together with his daughter, Ruth Manor, "Doctor's Errors and Mistakes of Medicine: Must Health Care Deteriorate?" (2004). Awards and legacy Wolman was a member of the Histochemical Society (USA), the Society for Experimental Biology and Medicine and the Israel Association of Pathologists and the