product. The United Kingdom has a three-tiered classification system: General Sale List (GSL) Pharmacy medicines (P) Prescription Only Medicines (POM) Within POM, certain agents with a high abuse/addiction liability are also separately scheduled under the Misuse of Drugs Act 1971 (amended with the Misuse of Drugs Regulations 2001); and are commonly known as Controlled Drugs (CD). United States Therapeutic goods in the United States are regulated by the U.S. Food and Drug Administration (FDA), which makes some drugs available over the counter (OTC) at retail outlets and others by prescription only. The prescription or possession of some substances is controlled or prohibited by the Controlled Substances Act, under the FDA and the Drug Enforcement Administration (DEA). Some US states apply more stringent limits on the prescription of certain controlled substances C-V and BTC (behind the counter) drugs such as pseudoephedrine. Three primary branches of pharmacovigilance in the U.S. include the FDA, the pharmaceutical manufacturers, and the academic/non-profit organizations (such as RADAR and Public Citizen). See also Council for International Organizations of Medical Sciences (CIOMS, WHO) Counterfeit drug Drug Efficacy Study Implementation (DESI) Drug policy and Drug prohibition law International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use Inverse benefit law List of stringent regulatory authorities Over-the-counter drug Prescription drug Uppsala Monitoring Centre (WHO) Validation (drug manufacture) World Health Organization Legal drug trade Illegal drug trade References External links Central Drugs Standard Control Organisation (India) Presentation on Drug License Audit Process in India Drug control law Drug safety Life sciences industry Pharmaceuticals policy