Research has pointed to anthraquinones found in noni roots, leaves and fruit as potentially toxic to the liver and other organs. In 2005, two published clinical case reports described incidents of acute hepatitis caused by ingesting Tahitian Noni juice. These case reports were reviewed in 2006 by the European Food Safety Authority (EFSA), which initially reported that data available at the time of the case reports were not sufficient to establish a causal relationship between consumption of the juice and hepatotoxicity; however, an increasing number of subsequent case reports suggested that some individuals may be particularly sensitive to hepatotoxic effects of noni fruit products. The U.S. National Center for Complementary and Integrative Health advised against consumption of noni products if one has a history of liver disorders. The potential for toxicity caused by noni juices remained under surveillance by EFSA, individual food safety authorities in France, Finland and Ireland, and medical investigators in Germany. Noni products may contain high amounts of potassium, leading to one advisory that people on potassium-restricted diets because of kidney problems should avoid using noni. American Cancer Society opinion Although noni plants and juices have been promoted by practitioners of alternative medicine as a cure for a number of human maladies including HIV, heart disease and cancer, the American Cancer Society concluded that "there is no reliable clinical evidence that noni juice is effective in preventing or treating cancer or any other disease in humans". See also List of unproven and disproven cancer treatments Tahitian Noni juice References Further reading Juice Pseudoscience