currently available treatments. The computations of this project target mycolic acids in the bacterium's protective coat, simulating the behaviour of these molecules to better understand how they offer protection to the bacteria. Smash Childhood Cancer Launched in January 2017, the Smash Childhood Cancer project builds on the work from the Help Fight Childhood Cancer project by looking for drug candidates targeting additional childhood cancers. Upon Dr. Akira Nakagawara's retirement in March 2020, the principal investigator changed to Dr. Godfrey Chan, who was one of the original members of the Smash Childhood Cancer team. Additionally, PRDM14 and Fox01 have been added as new targets for investigation. An inhibitor of the osteopontin protein was modeled. Africa Rainfall Project The Africa Rainfall Project (launched October 2019) will use the computing power of World Community Grid, data from The Weather Company, and other data to improve rainfall modelling, which can help farmers in sub-Saharan Africa successfully raise their crops. The amount of RAM that can be involved in calculations is from 1 to 16 gigabytes. Completed subprojects Human Proteome Folding – Phase 1 The first project launched on World Community Grid was the Human Proteome Folding Project, or HPF1, which aims to predict the structure of human proteins. The project was launched on November 16, 2004, and completed on July 18, 2006. This project was unique in that computation was done in tandem with the grid.org distributed computing project. Devised by Richard Bonneau at the Institute for Systems Biology, the project used grid computing to produce the likely structures for each of the proteins using a Rosetta Score. From these predictions, researchers hope to predict the function of the myriad proteins. This increased understanding of the human proteins could prove vital in the search for cures to human diseases. Computing for this project was officially completed on July 18, 2006. Research results for the yeast portion of HPF1 have been published. Human Proteome Folding – Phase 2 Human Proteome Folding - Phase 2 (HPF2) (launched June 23, 2006) was the third project to run on World Community Grid, and completed in 2013. This project, following on from HPF1, focused on human-secreted proteins, with special focus on biomarkers and the proteins on the surface of cells as well as Plasmodium, the organism that causes malaria. HPF2 generates higher-resolution protein models than HPF1. Though these higher-resolution models are more useful, they also require more processing power