This is a rare cancer. This report suggested that follow up of sinus polyps in this syndrome may be indicated. Monitoring Some suggestions for surveillance for cancer include the following: Small intestine with small bowel radiography every 2 years, Esophagogastroduodenoscopy and colonoscopy every 2 years, CT scan or MRI of the pancreas yearly, Ultrasound of the pelvis and testes yearly Mammography from age 25 annually Papanicolaou smear (Pap smear) annually beginning at age 18-20 Follow-up care should be supervised by a physician familiar with Peutz–Jeghers syndrome. Genetic consultation and counseling as well as urological and gynecological consultations are often needed. Eponym First described in a published case report in 1921 by Jan Peutz (1886–1957), a Dutch Internist, it was later formalized into the syndrome by American physicians at Boston City Hospital, Harold Joseph Jeghers (1904–1990) and Kermit Harry Katz (1914–2003), and Victor Almon McKusick (1921–2008) in 1949 and published in the New England Journal of Medicine. See also List of cutaneous conditions Sex cord tumour with annular tubules References External links GeneReviews/NCBI/NIH/UW entry on Peutz-Jeghers syndrome Peutz-Jeghers syndrome – Genetics Home Reference Autosomal dominant disorders Gastrointestinal tract disorders Deficiencies of intracellular signaling peptides and proteins Gynaecological neoplasia Syndromes affecting the gastrointestinal tract Urological conditions Disturbances of human pigmentation Melanocytic nevi and neoplasms Oral mucosal pathology Diseases named for discoverer