with CIPA die of hyperthermia by age 3. Anaesthetic Management Some patients have been operated without anesthesia, but anxiety might still need to be alleviated. Patients might have tactical hyperesthesia, in which case anesthesia necessary. Bradycardia, hypotension, and hyperthermia also require management/attention, before, during and after surgery. References Further reading Autosomal recessive disorders Neurocutaneous conditions Peripheral nervous system disorders Rare diseases