of origin of cancers of unknown primary, allograft rejection, and resistance to hormone therapy. Computational prediction DNA methylation can also be detected by computational models through sophisticated algorithms and methods. Computational models can facilitate the global profiling of DNA methylation across chromosomes, and often such models are faster and cheaper to perform than biological assays. Such up-to-date computational models include Bhasin, et al., Bock, et al., and Zheng, et al. Together with biological assay, these methods greatly facilitate the DNA methylation analysis. See also 5-Hydroxymethylcytosine 5-Methylcytosine 7-Methylguanosine Decrease in DNA Methylation I (DDM1), a plant methylation gene Demethylating agent Differentially methylated regions DNA demethylation DNA methylation reprogramming Epigenetics, of which DNA methylation is a significant contributor Epigenetic clock, a method to calculate age based on DNA methylation Epigenome Genome Genomic imprinting, an inherited repression of an allele, relying on DNA methylation MethBase DNA Methylation database hosted on the UCSC Genome Browser MethDB DNA Methylation database N6-Methyladenosine References Further reading External links ENCODE threads explorer Non-coding RNA characterization. Nature (journal) PCMdb Pancreatic Cancer Methylation Database. SMART Specific Methylation Analysis and Report Tool Human Methylation Mark Atlas DiseaseMeth Human disease methylation database EWAS Atlas A knowledgebase of epigenome-wide association studies DNA Epigenetics fr:Méthylation#La méthylation de l'ADN