as The Boss, the Creator of the Universe William H. Macy as Glenn, an angel Mel Brooks as Joe Snow (voice only), parodying Sam the Snowman from Rudolph the Red-Nosed Reindeer Chantal Strand as Nancy Nut-What Dave "Squatch" Ward as Sally Ann Santa Claus Muppets performers Steve Whitmire as Kermit the Frog, Rizzo the Rat, Beaker, Bean Bunny Dave Goelz as The Great Gonzo, Dr. Bunsen Honeydew, Waldorf, Zoot, Beauregard Bill Barretta as Pepé the King Prawn, Bobo the Bear, Johnny Fiama, Swedish Chef, Lew Zealand, Howard Tubman, Rowlf the Dog Eric Jacobson as Miss Piggy, Fozzie Bear, Animal, Yoda Brian Henson as Scooter, Janice, Sal Minella Kevin Clash as Sam Eagle John Henson as Sweetums John Kennedy as Dr. Teeth Jerry Nelson as Robin the Frog, Statler, Floyd Pepper, Announcer Allan Trautman as Joe Snow (puppetry only), Eugene the Tuba Player Additional Muppet Performers: Alice Dinnean, Geoff Redknap, Denise Cheshire, Drew Massey, Adam Behr, and Gord Robertson. Cameo guest stars Zach Braff as Himself/Dr. John "J.D." Dorian Sarah Chalke as Herself/Dr. Elliot Reid Carson Daly as Himself Snoop Dogg as Himself (deleted scene) Neil Flynn as Himself/Janitor Bill Lawrence as Himself John C. McGinley as Himself/Dr. Perry Cox Judy Reyes as Herself/Nurse Carla Espinosa Kelly Ripa as Herself Joe Rogan as Himself Molly Shannon as Herself Robert Smigel as Triumph the Insult Comic Dog Production notes Veteran Muppet performer Jerry Nelson was ill during filming, so most of his characters were puppeteered on set by others and later dubbed by Nelson in post-production. The exception was Nelson's character Lew Zealand, who was performed by Bill Barretta. Sam Eagle, a character originally performed by Frank Oz, was voiced in the film by Kevin Clash, while John Kennedy provided the on set puppetry. Scooter, performed in the film by Brian Henson, makes his first major appearance since the death of his initial performer, Richard Hunt. Hunt's character Janice was also performed by Henson and has a speaking role for the first time since Hunt's death. The film contains an original song, "Everyone Matters", performed by Kermit and Gonzo as part of the world in which he had never been born, and then reprised at the end. The film also makes reference to the classic Muppet song "Rainbow Connection", featuring a statue of Kermit in a park, erected in dedication "for the lovers, the dreamers and you". The movie was filmed prior