| February 1 | Minnesota | | Paul Pierce (36) | Kendrick Perkins (11) | Rajon Rondo (8) | TD Banknorth Garden18,624 | 40–9 |- bgcolor="#bbffbb" | 50 | February 3 | @ Philadelphia | | Paul Pierce (29) | Glen Davis (11) | Rajon Rondo (8) | Wachovia Center16,831 | 41–9 |- bgcolor="#ffcccc" | 51 | February 5 | L. A. Lakers | | Ray Allen (22) | Kendrick Perkins (9) | Rajon Rondo (12) | TD Banknorth Garden18,624 | 41–10 |- bgcolor="#bbffbb" | 52 | February 6 | @ New York | | Paul Pierce (26) | Kevin Garnett (11) | Rajon Rondo (7) | Madison Square Garden19,763 | 42–10 |- bgcolor="#ffcccc" | 53 | February 8 | San Antonio | | Kevin Garnett (26) | Kevin Garnett (12) | Rajon Rondo (16) | TD Banknorth Garden18,624 | 42–11 |- bgcolor="#bbffbb" | 54 | February 11 | @ New Orleans | | Paul Pierce (30) | Kevin Garnett (10) | Rajon Rondo (11) | New Orleans Arena18,080 | 43–11 |- bgcolor="#bbffbb" | 55 | February 12 | @ Dallas | | Paul Pierce (31) | Rajon Rondo (15) | Rajon Rondo (14) | American Airlines Center20,285 | 44–11 |- align="center" | colspan="9" style="background:#bbcaff;" | All-Star Break |- bgcolor="#ffcccc" | 56 | February 19 | @ Utah | | Paul Pierce (20) | Kendrick Perkins (11) | Rajon Rondo (7) | EnergySolutions Arena19,911 | 44–12 |- bgcolor="#bbffbb" | 57 | February 22 | @ Phoenix | | Rajon Rondo (32) | Eddie House, Rajon Rondo, Paul Pierce, Kendrick Perkins, Leon Powe (6) | Rajon Rondo (10) | US Airways Center18,422 | 45–12 |- bgcolor="#bbffbb" | 58 | February 23 | @ Denver | | Ray Allen (26) | Rajon Rondo (8) | Rajon Rondo (8) | Pepsi Center19,784 | 46–12 |- bgcolor="#ffcccc" | 59 | February 25 | @ L. A. Clippers | | Paul Pierce (20) | Kendrick Perkins, Leon Powe (9) | Ray Allen (6) | Staples Center18,609 | 46–13 |- bgcolor="#bbffbb" | 60 | February 27 | Indiana | | Ray Allen (30) | Kendrick Perkins (11) | Rajon Rondo (17) | TD Banknorth Garden18,624 | 47–13 |- bgcolor="#ffcccc" | 61 | March 1 | Detroit | | Paul Pierce (26) | Glen Davis, Rajon Rondo, Paul Pierce, Kendrick Perkins (6) | Rajon Rondo (6) | TD Banknorth Garden18,624 | 47–14 |- bgcolor="#bbffbb" | 62 |