Center18,422 | 1–2 |- bgcolor="#ffcccc" | 4 | November 5 | @ Utah | | Brandon Roy, LaMarcus Aldridge (18) | Joel Przybilla (16) | Brandon Roy (6) | EnergySolutions Arena19,911 | 1–3 |- bgcolor="#bbffbb" | 5 | November 6 | Houston | | LaMarcus Aldridge (27) | Travis Outlaw (13) | Steve Blake (8) | Rose Garden20,611 | 2–3 |- bgcolor="#bbffbb" | 6 | November 8 | Minnesota | | LaMarcus Aldridge, Brandon Roy (24) | LaMarcus Aldridge (13) | Brandon Roy (9) | Rose Garden20,599 | 3–3 |- bgcolor="#bbffbb" | 7 | November 10 | @ Orlando | | Brandon Roy (27) | LaMarcus Aldridge (11) | Steve Blake, Brandon Roy, Sergio Rodríguez (4) | Amway Arena14,210 | 4–3 |- bgcolor="#bbffbb" | 8 | November 12 | @ Miami | | Rudy Fernández (25) | Joel Przybilla (10) | Sergio Rodríguez (5) | American Airlines Arena15,021 | 5–3 |- bgcolor="#ffcccc" | 9 | November 14 | @ New Orleans | | Brandon Roy (21) | Greg Oden (11) | Sergio Rodríguez (7) | New Orleans Arena16,071 | 5–4 |- bgcolor="#bbffbb" | 10 | November 15 | @ Minnesota | | Brandon Roy (24) | Greg Oden, Joel Przybilla (8) | Brandon Roy (6) | Target Center12,213 | 6–4 |- bgcolor="#ffcccc" | 11 | November 18 | @ Golden State | | Brandon Roy, Greg Oden (22) | Greg Oden (10) | Brandon Roy (9) | Oracle Arena18,284 | 6–5 |- bgcolor="#bbffbb" | 12 | November 19 | Chicago | | Brandon Roy (20) | Greg Oden (10) | Sergio Rodríguez (9) | Rose Garden20,599 | 7–5 |- bgcolor="#bbffbb" | 13 | November 21 | @ Sacramento | | Steve Blake (20) | Joel Przybilla (10) | Steve Blake (5) | ARCO Arena12,056 | 8–5 |- bgcolor="#ffcccc" | 14 | November 22 | @ Phoenix | | Brandon Roy (26) | Channing Frye, Joel Przybilla (8) | Steve Blake (5) | US Airways Center18,422 | 8–6 |- bgcolor="#bbffbb" | 15 | November 24 | Sacramento | | Brandon Roy (28) | Joel Przybilla (12) | Steve Blake (5) | Rose Garden20,467 | 9–6 |- bgcolor="#bbffbb" | 16 | November 26 | Miami | | Channing Frye (17) | Greg Oden (10) | Sergio Rodríguez (11) | Rose Garden20,528 | 10–6 |- bgcolor="#bbffbb" | 17 | November 28 | New Orleans | | Brandon Roy (25) | Greg Oden (8)