ARCO Arena10,593 | 4–20 |- bgcolor="#ffcccc" | 25 | December 17 | Cleveland | | Al Jefferson (20) | Al Jefferson (11) | Randy Foye (3) | Target Center14,899 | 4–21 |- bgcolor="#ffcccc" | 26 | December 20 | Houston | | Al Jefferson (34) | Al Jefferson (13) | Al Jefferson, Rashad McCants (4) | Target Center12,115 | 4–22 |- bgcolor="#ffcccc" | 27 | December 23 | @ San Antonio | | Al Jefferson (28) | Randy Foye (16) | Kevin Ollie (4) | AT&T Center17,996 | 4–23 |- bgcolor="#bbffbb" | 28 | December 26 | @ New York | | Rashad McCants (23) | Al Jefferson (15) | Sebastian Telfair (8) | Madison Square Garden19,763 | 5–23 |- bgcolor="#ffcccc" | 29 | December 27 | Orlando | | Rashad McCants (21) | Kevin Love (10) | Rashad McCants (4) | Target Center17,003 | 5–24 |- bgcolor="#bbffbb" | 30 | December 29 | Memphis | | Al Jefferson (38) | Al Jefferson (16) | Randy Foye, Craig Smith (5) | Target Center12,207 | 6–24 |- bgcolor="#ffcccc" | 31 | December 30 | @ Dallas | | Al Jefferson (21) | Al Jefferson (9) | Kevin Ollie (6) | American Airlines Center20,264 | 6–25 |- bgcolor="#bbffbb" | 32 | January 2 | Golden State | | Al Jefferson (32) | Al Jefferson, Ryan Gomes (10) | Randy Foye (7) | Target Center11,921 | 7–25 |- bgcolor="#bbffbb" | 33 | January 3 | @ Chicago | | Randy Foye (21) | Al Jefferson (14) | Sebastian Telfair (6) | United Center20,516 | 8–25 |- bgcolor="#bbffbb" | 34 | January 6 | @ Memphis | | Randy Foye (23) | Al Jefferson (12) | Sebastian Telfair (9) | FedExForum10,156 | 9–25 |- bgcolor="#bbffbb" | 35 | January 7 | Oklahoma City | | Randy Foye (32) | Kevin Love (15) | Randy Foye (6) | Target Center10,272 | 10–25 |- bgcolor="#bbffbb" | 36 | January 10 | Milwaukee | | Rodney Carney (22) | Kevin Love (12) | Sebastian Telfair (11) | Target Center15,007 | 11–25 |- bgcolor="#ffcccc" | 37 | January 13 | Miami | | Randy Foye (29) | Al Jefferson (10) | Randy Foye (8) | Target Center10,856 | 11–26 |- bgcolor="#bbffbb" | 38 | January 16 | @ Phoenix | | Al Jefferson (22) | Kevin Love (14) | Mike Miller (5) | US Airways Center18,422 | 12–26