In enzymology, a diaminopimelate dehydrogenase () is an enzyme that catalyzes the chemical reaction meso-2,6-diaminoheptanedioate + H2O + NADP+ L-2-amino-6-oxoheptanedioate + NH3 + NADPH + H+ The 3 substrates of this enzyme are meso-2,6-diaminoheptanedioate, H2O, and NADP+, whereas its 4 products are L-2-amino-6-oxoheptanedioate, NH3, NADPH, and H+. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH2 group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is meso-2,6-diaminoheptanedioate:NADP+ oxidoreductase (deaminating). Other names in common use include meso-alpha,epsilon-diaminopimelate dehydrogenase, and meso-diaminopimelate dehydrogenase. This enzyme participates in lysine biosynthesis. Structural studies As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes , , , and . References EC 1.4.1 NADPH-dependent enzymes Enzymes of known structure