|| September 5 || Cubs || 4–1 || Terry Mulholland (8–8) || Steve Wilson (4–8) || Roger McDowell (19) || 16,177 || 63–72 |- style="background:#fbb" | 136 || September 6 || Cubs || 2–5 || José Núñez (2–6) || Jason Grimsley (1–1) || Mitch Williams (14) || 13,849 || 63–73 |- style="background:#bfb" | 137 || September 7 || Mets || 4–1 || José DeJesús (5–6) || David Cone (11–8) || None || 29,744 || 64–73 |- style="background:#fbb" | 138 || September 8 || Mets || 2–12 || Dwight Gooden (16–6) || Bruce Ruffin (6–13) || None || 37,489 || 64–74 |- style="background:#bfb" | 139 || September 9 || Mets || 6–2 || Pat Combs (7–9) || Sid Fernandez (9–12) || Joe Boever (12) || 36,502 || 65–74 |- style="background:#fbb" | 140 || September 10 || Pirates || 2–3 || Stan Belinda (3–4) || Joe Boever (3–6) || None || 18,970 || 65–75 |- style="background:#fbb" | 141 || September 11 || Pirates || 1–5 || Randy Tomlin (3–2) || Jason Grimsley (1–2) || None || 20,289 || 65–76 |- style="background:#fbb" | 142 || September 12 || @ Cubs || 3–9 || Greg Maddux (13–13) || José DeJesús (5–7) || None || 16,258 || 65–77 |- style="background:#fbb" | 143 || September 13 || @ Cubs || 5–6 || Paul Assenmacher (5–2) || Roger McDowell (6–7) || Les Lancaster (6) || 15,495 || 65–78 |- style="background:#bfb" | 144 || September 14 || @ Mets || 4–1 || Pat Combs (8–9) || Sid Fernandez (9–13) || None || 36,339 || 66–78 |- style="background:#fbb" | 145 || September 15 || @ Mets || 2–4 || Frank Viola (19–9) || Terry Mulholland (8–9) || John Franco (33) || 45,202 || 66–79 |- style="background:#bfb" | 146 || September 16 || @ Mets || 8–3 || José DeJesús (6–7) || David Cone (12–9) || None || 44,813 || 67–79 |- style="background:#bfb" | 147 || September 18 || @ Cardinals || 6–3 || Jason Grimsley (2–2) || Bob Tewksbury (10–7) || Joe Boever (13) || 15,588 || 68–79 |- style="background:#bfb" | 148 || September 19 || @ Cardinals || 8–4 || Pat Combs (9–9) || Joe Magrane (9–16) || None || 15,828 || 69–79 |- style="background:#fbb" | 149 || September 20 || @ Cardinals || 4–5 || Mike Pérez (1–0) || Roger McDowell (6–8) || None || 14,744 || 69–80 |- style="background:#bfb" | 150 || September 21 || Expos