Phosphatidylinositol 3-kinase regulatory subunit beta is an enzyme that in humans is encoded by the PIK3R2 gene. A recent study on gene expression indicated that the PIK3R2 gene might have a key role in pan-cancer prognosis. Interactions PIK3R2 has been shown to interact with: CRKL Cbl gene, Epidermal growth factor, FYN, HER2/neu, Macrophage colony-stimulating factor, and PIK3CD. Clinical relevance PIK3R2 mutations were recently shown to be associated with polymicrogyria. References Further reading