Pirates || 2–3 || Bruce Kison (2–0) || Steve Carlton (0–3) || Dave Giusti (2) || 5,726 || 6–8 |- style="background:#fbb" | 15 || April 26 || @ Pirates || 3–7 || Jim Rooker (2–0) || Wayne Twitchell (1–3) || None || 13,120 || 6–9 |- style="background:#fbb" | 16 || April 27 || @ Pirates || 0–2 || Dock Ellis (1–2) || Tom Underwood (2–2) || None || 14,074 || 6–10 |- style="background:#bfb" | 17 || April 29 || Expos || 5–0 || Jim Lonborg (2–1) || Dennis Blair (0–3) || None || 5,477 || 7–10 |- style="background:#bfb" | 18 || April 30 || Expos || 2–1 || Steve Carlton (1–3) || Steve Rogers (0–4) || None || 8,750 || 8–10 |- |- style="background:#bfb" | 19 || May 2 || Pirates || 9–5 || Wayne Twitchell (2–3) || Bruce Kison (2–1) || Tug McGraw (1) || 20,257 || 9–10 |- style="background:#bfb" | 20 || May 3 (1) || Pirates || 6–2 || Tom Underwood (3–2) || Jim Rooker (2–1) || Gene Garber (2) || see 2nd game || 10–10 |- style="background:#bfb" | 21 || May 3 (2) || Pirates || 4–3 (11) || Tug McGraw (1–0) || Ramón Hernández (0–1) || None || 44,501 || 11–10 |- style="background:#bbb" | – || May 4 || Pirates || colspan=6 | Postponed (rain); Makeup: June 24 as a traditional double-header |- style="background:#fbb" | 22 || May 5 || @ Cardinals || 3–11 || Bob Gibson (1–3) || Steve Carlton (1–4) || None || 9,198 || 11–11 |- style="background:#bbb" | – || May 6 || @ Cardinals || colspan=6 | Postponed (rain); Makeup: July 25 as a traditional double-header |- style="background:#bfb" | 23 || May 7 || @ Cardinals || 4–1 || Wayne Twitchell (3–3) || Bob Forsch (2–3) || Tug McGraw (2) || 9,735 || 12–11 |- style="background:#bfb" | 24 || May 8 || @ Cardinals || 6–2 || Jim Lonborg (3–1) || John Denny (2–2) || None || 10,293 || 13–11 |- style="background:#fbb" | 25 || May 9 || @ Braves || 1–3 || Roric Harrison (2–1) || Tom Underwood (3–3) || None || 7,444 || 13–12 |- style="background:#fbb" | 26 || May 10 || @ Braves || 1–2 (11) || Phil Niekro (2–3) || Gene Garber (1–2) || None || 6,510 || 13–13 |- style="background:#fbb" | 27 || May 11 || @ Braves || 3–7 || Buzz Capra (3–4) || Wayne