style="background:#fbb" | 41 || June 1 (2) || Cubs || 0–1 || Jake Mooty (3–1) || Lee Grissom (0–3) || None || 4,365 || 12–29 |- style="background:#bfb" | 42 || June 2 || Cubs || 3–2 || Johnny Podgajny (3–2) || Larry French (2–6) || None || 1,000 || 13–29 |- style="background:#bfb" | 43 || June 3 || Cubs || 7–0 || Tommy Hughes (3–4) || Bill Lee (5–5) || None || 1,000 || 14–29 |- style="background:#bbb" | – || June 4 || Reds || colspan=6 | Postponed (rain and wet grounds); Makeup: July 19 as a traditional double-header |- style="background:#bbb" | – || June 5 || Reds || colspan=6 | Postponed (rain); Makeup: August 18 as a traditional double-header |- style="background:#fbb" | 44 || June 6 || Reds || 0–7 || || Si Johnson (1–2) || None || 7,044 || 14–30 |- style="background:#bfb" | 45 || June 7 || Pirates || 2–0 || Cy Blanton (5–1) || Johnny Lanning (1–3) || None || 3,802 || 15–30 |- style="background:#fbb" | 46 || June 8 (1) || Pirates || 2–12 || Joe Bowman (2–1) || Tommy Hughes (3–5) || Rip Sewell (1) || see 2nd game || 15–31 |- style="background:#bfb" | 47 || June 8 (2) || Pirates || 5–2 || Johnny Podgajny (4–2) || Russ Bauers (1–3) || None || 11,604 || 16–31 |- style="background:#fbb" | 48 || June 9 || Pirates || 0–5 || Lefty Wilkie (2–1) || Lee Grissom (0–4) || None || 892 || 16–32 |- style="background:#fbb" | 49 || June 10 || Cardinals || 0–3 || Lon Warneke (7–1) || Si Johnson (1–3) || None || 3,792 || 16–33 |- style="background:#fbb" | 50 || June 11 || Cardinals || 2–3 (10) || Howie Krist (5–0) || Boom-Boom Beck (0–3) || None || 6,710 || 16–34 |- style="background:#fbb" | 51 || June 14 || @ Cubs || 0–3 || Vern Olsen (3–2) || Cy Blanton (5–2) || None || 2,838 || 16–35 |- style="background:#fbb" | 52 || June 15 (1) || @ Cubs || 0–6 || Claude Passeau (6–5) || Tommy Hughes (3–6) || None || see 2nd game || 16–36 |- style="background:#bfb" | 53 || June 15 (2) || @ Cubs || 8–4 || Johnny Podgajny (5–2) || Charlie Root (4–3) || None || 7,001 || 17–36 |- style="background:#fbb" | 54 || June 16 || @ Cubs || 1–3 || Jake Mooty (4–2) || Lee Grissom