McGraw (1) || 16,441 || 1–1 |- style="background:#fbb" | 3 || April 9 || @ Cubs || 0–2 || Bill Bonham (1–0) || Ron Schueler (0–1) || None || 30,601 || 1–2 |- style="background:#fbb" | 4 || April 10 || @ Cubs || 6–7 || Ray Burris (1–0) || Mac Scarce (1–1) || None || 6,535 || 1–3 |- style="background:#bfb" | 5 || April 11 || @ Cubs || 4–3 || Frank Linzy (1–0) || Horacio Piña (0–1) || Eddie Watt (1) || 2,292 || 2–3 |- style="background:#bbb" | – || April 13 || @ Mets || colspan=6 | Postponed (rain); Makeup: April 14 as a traditional double-header |- style="background:#bfb" | 6 || April 14 (1) || @ Mets || 2–1 (11) || Mike Wallace (1–0) || Tug McGraw (0–2) || None || see 2nd game || 3–3 |- style="background:#bfb" | 7 || April 14 (2) || @ Mets || 5–3 || Mac Scarce (2–1) || Bob Miller (0–1) || None || 14,201 || 4–3 |- style="background:#bfb" | 8 || April 15 || Cardinals || 3–2 || Dick Ruthven (1–0) || Alan Foster (0–1) || Mac Scarce (1) || 6,713 || 5–3 |- style="background:#bfb" | 9 || April 16 || Cardinals || 10–3 || Steve Carlton (1–0) || Bob Gibson (0–1) || None || 8,107 || 6–3 |- style="background:#bfb" | 10 || April 17 || Cardinals || 12–5 || George Culver (1–0) || Sonny Siebert (1–1) || None || 11,237 || 7–3 |- style="background:#fbb" | 11 || April 18 || Cardinals || 2–6 || Lynn McGlothen (2–0) || Ron Schueler (0–2) || None || 8,106 || 7–4 |- style="background:#bfb" | 12 || April 19 || Cubs || 9–2 || Jim Lonborg (1–1) || Bill Bonham (1–2) || None || 12,318 || 8–4 |- style="background:#fbb" | 13 || April 20 || Cubs || 4–5 (13) || Ray Burris (2–0) || Mac Scarce (2–2) || None || 16,534 || 8–5 |- style="background:#bfb" | 14 || April 21 || Cubs || 7–3 || Steve Carlton (2–0) || Burt Hooton (1–1) || None || 17,172 || 9–5 |- style="background:#fbb" | 15 || April 23 || @ Dodgers || 3–5 || Jim Brewer (2–0) || Frank Linzy (1–1) || None || 14,984 || 9–6 |- style="background:#fbb" | 16 || April 24 || @ Dodgers || 1–6 || Don Sutton (4–1) || Jim Lonborg (1–2) || None || 14,756 || 9–7 |- style="background:#fbb" | 17 ||