|- style="background:#fbb" | 6 || April 13 || Cubs || 2–5 || Jamie Moyer (1–0) || Don Carman (0–1) || Lee Smith (1) || 15,366 || 1–5 |- style="background:#fbb" | 7 || April 14 || Mets || 5–7 || Ron Darling (1–0) || Steve Bedrosian (1–1) || Jesse Orosco (3) || 22,836 || 1–6 |- style="background:#fbb" | 8 || April 15 || Mets || 1–4 || Sid Fernandez (2–0) || Kevin Gross (0–2) || Doug Sisk (2) || 21,995 || 1–7 |- style="background:#fbb" | 9 || April 16 || Mets || 3–9 || Rick Aguilera (1–0) || Joe Cowley (0–2) || None || 16,350 || 1–8 |- style="background:#bfb" | 10 || April 17 || @ Pirates || 6–2 (10) || Steve Bedrosian (2–1) || Barry Jones (0–1) || None || 10,105 || 2–8 |- style="background:#bfb" | 11 || April 18 || @ Pirates || 8–6 || Kent Tekulve (1–0) || Don Robinson (2–1) || None || 19,361 || 3–8 |- style="background:#fbb" | 12 || April 19 || @ Pirates || 2–5 || Doug Drabek (1–1) || Bruce Ruffin (0–1) || Don Robinson (2) || 7,962 || 3–9 |- style="background:#bfb" | 13 || April 20 || @ Expos || 4–3 || Dan Schatzeder (1–1) || Jay Tibbs (1–2) || Kent Tekulve (1) || 50,482 || 4–9 |- style="background:#fbb" | 14 || April 22 || @ Expos || 3–7 || Neal Heaton (2–1) || Joe Cowley (0–3) || None || 8,114 || 4–10 |- style="background:#fbb" | 15 || April 23 || @ Expos || 5–6 || Randy St. Claire (1–0) || Mike Jackson (0–1) || Andy McGaffigan (2) || 5,632 || 4–11 |- style="background:#bbb" | – || April 24 || Pirates || colspan=6 | Postponed (rain); Makeup: June 29 as a traditional double-header |- style="background:#bfb" | 16 || April 25 || Pirates || 3–2 || Don Carman (1–1) || Doug Drabek (1–2) || Kent Tekulve (2) || 18,553 || 5–11 |- style="background:#bfb" | 17 || April 26 || Pirates || 6–4 || Bruce Ruffin (1–1) || Rick Reuschel (0–1) || Steve Bedrosian (1) || 30,234 || 6–11 |- style="background:#fbb" | 18 || April 27 || Expos || 4–6 || Neal Heaton (3–1) || Kevin Gross (0–3) || Randy St. Claire (3) || 15,149 || 6–12 |- style="background:#fbb" | 19 || April 28 || Expos || 1–7 || Floyd Youmans (1–2) || Joe Cowley (0–4) || Andy McGaffigan (3) || 11,598 || 6–13