Astros || 5–1 || Curt Schilling (4–3) || Ramón García (2–2) || None || 12,179 || 10–20 |- style="background:#fbb" | 31 || May 7 || @ Cardinals || 7–14 || John Frascatore (2–1) || Reggie Harris (0–2) || None || 23,388 || 10–21 |- style="background:#fbb" | 32 || May 8 || @ Cardinals || 2–6 || Andy Benes (2–1) || Mike Mimbs (0–3) || None || 32,264 || 10–22 |- style="background:#bfb" | 33 || May 9 || Rockies || 3–1 || Calvin Maduro (3–3) || Roger Bailey (4–2) || Ricky Bottalico (7) || 13,564 || 11–22 |- style="background:#bfb" | 34 || May 10 || Rockies || 5–4 (10) || Ricky Bottalico (1–1) || Steve Reed (0–1) || None || 17,629 || 12–22 |- style="background:#bfb" | 35 || May 11 || Rockies || 3–1 || Curt Schilling (5–3) || John Thomson (0–1) || None || 21,282 || 13–22 |- style="background:#fbb" | 36 || May 12 || Rockies || 2–9 || Mike DeJean (1–0) || Bobby Muñoz (1–5) || None || 12,603 || 13–23 |- style="background:#bfb" | 37 || May 13 || Cardinals || 3–2 || Jerry Spradlin (1–1) || T. J. Mathews (1–2) || Ricky Bottalico (8) || 14,416 || 14–23 |- style="background:#fbb" | 38 || May 14 || Cardinals || 3–12 || Todd Stottlemyre (2–2) || Calvin Maduro (3–4) || None || 14,799 || 14–24 |- style="background:#fbb" | 39 || May 16 || Astros || 7–12 || Chris Holt (5–3) || Mark Leiter (3–4) || None || 13,456 || 14–25 |- style="background:#bfb" | 40 || May 17 || Astros || 4–2 || Curt Schilling (6–3) || Shane Reynolds (4–4) || Ricky Bottalico (9) || 17,138 || 15–25 |- style="background:#bfb" | 41 || May 18 || Astros || 5–3 || Garrett Stephenson (1–0) || Mike Hampton (2–4) || Ricky Bottalico (10) || 17,367 || 16–25 |- style="background:#fbb" | 42 || May 19 || Astros || 5–9 || Darryl Kile (4–2) || Calvin Maduro (3–5) || None || 15,122 || 16–26 |- style="background:#bfb" | 43 || May 20 || @ Cubs || 3–2 || Mark Leiter (4–4) || Frank Castillo (2–6) || Ricky Bottalico (11) || 20,186 || 17–26 |- style="background:#fbb" | 44 || May 21 || @ Cubs || 0–7 || Kevin Foster (5–3) || Edgar Ramos (0–1) || None || 22,881 || 17–27 |- style="background:#fbb" | 45 || May 22 || Mets || 3–10 || Bobby J. Jones (8–2) ||