|| 12–3 || Ron Reed (4–1) || Vida Blue (6–3) || None || 32,585 || 22–9 |- style="background:#fbb" | 33 || May 15 || @ Cubs || 1–7 || Lynn McGlothen (5–4) || Nino Espinosa (5–2) || None || 13,834 || 22–10 |- style="background:#bfb" | 34 || May 16 || @ Cubs || 13–0 || Steve Carlton (4–5) || Rick Reuschel (2–5) || None || 18,015 || 23–10 |- style="background:#bfb" | 35 || May 17 || @ Cubs || 23–22 (10) || Rawly Eastwick (1–0) || Bruce Sutter (1–1) || None || 14,952 || 24–10 |- style="background:#fbb" | 36 || May 18 || Expos || 3–5 || Stan Bahnsen (1–1) || Dick Ruthven (6–1) || Elías Sosa (4) || 31,481 || 24–11 |- style="background:#fbb" | 37 || May 19 || Expos || 5–10 || Rudy May (2–0) || Rawly Eastwick (1–1) || Dan Schatzeder (1) || 33,212 || 24–12 |- style="background:#fbb" | 38 || May 20 || Expos || 6–10 || Stan Bahnsen (2–1) || Nino Espinosa (5–3) || Elías Sosa (5) || 48,631 || 24–13 |- style="background:#bfb" | 39 || May 21 || Cardinals || 5–3 || Steve Carlton (5–5) || John Denny (3–3) || None || 28,192 || 25–13 |- style="background:#bfb" | 40 || May 22 || Cardinals || 3–1 || Tug McGraw (2–0) || Bob Forsch (1–4) || None || 33,379 || 26–13 |- style="background:#fbb" | 41 || May 23 || Cardinals || 1–3 || Silvio Martínez (2–1) || Dick Ruthven (6–2) || Mark Littell (3) || 32,349 || 26–14 |- style="background:#fbb" | 42 || May 25 || Cubs || 0–3 || Lynn McGlothen (6–5) || Nino Espinosa (5–4) || Bruce Sutter (8) || 34,456 || 26–15 |- style="background:#fbb" | 43 || May 26 || Cubs || 1–4 || Dennis Lamp (4–1) || Larry Christenson (0–1) || Dick Tidrow (3) || 32,313 || 26–16 |- style="background:#bfb" | 44 || May 27 || Cubs || 6–4 || Steve Carlton (6–5) || Bill Caudill (0–1) || None || 47,087 || 27–16 |- style="background:#fbb" | 45 || May 28 || Cubs || 1–4 || Dick Tidrow (3–1) || Randy Lerch (2–3) || Bruce Sutter (9) || 51,381 || 27–17 |- style="background:#fbb" | 46 || May 29 || @ Expos || 0–9 || Steve Rogers (5–2) || Dick Ruthven (6–3) || None || 32,078 || 27–18 |- style="background:#fbb" | 47 || May 30 || @ Expos || 0–2 || Bill Lee