In enzymology, a p-benzoquinone reductase (NADPH) () is an enzyme that catalyzes the chemical reaction NADPH + H+ + p-benzoquinone NADP+ + hydroquinone The 3 substrates of this enzyme are NADPH, H+, and p-benzoquinone, whereas its two products are NADP+ and hydroquinone. This enzyme belongs to the family of oxidoreductases, specifically those acting on NADH or NADPH with a quinone or similar compound as acceptor. The systematic name of this enzyme class is NADPH:p-benzoquinone oxidoreductase. This enzyme participates in gamma-hexachlorocyclohexane degradation. References EC 1.6.5 NADPH-dependent enzymes Enzymes of unknown structure