In enzymology, a glutamate synthase (ferredoxin) () is an enzyme that catalyzes the chemical reaction 2 L-glutamate + 2 oxidized ferredoxin L-glutamine + 2-oxoglutarate + 2 reduced ferredoxin + 2 H+ Thus, the two substrates of this enzyme are L-glutamate and oxidized ferredoxin, whereas its 4 products are L-glutamine, 2-oxoglutarate, reduced ferredoxin, and H+. Classification This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH2 group of donors with an iron-sulfur protein as acceptor. Nomenclature The systematic name of this enzyme class is L-glutamate:ferredoxin oxidoreductase (transaminating). Other names in common use include: ferredoxin-dependent glutamate synthase, ferredoxin-glutamate synthase, glutamate synthase (ferredoxin-dependent), and ferredoxin-glutamine oxoglutarate aminotransferase (Fd-GOGAT). Biological role This enzyme participates in nitrogen metabolism. It has 5 cofactors: FAD, iron, sulfur, iron-sulfur, and flavoprotein. See also Glutamate synthase (NADH) Glutamate synthase (NADPH) References Flavoproteins Iron enzymes Sulfur enzymes Iron-sulfur enzymes Enzymes of known structure EC 1.4.7