M3 muscarinic receptor signalling, resulting in increased Gαq activity. The M3 muscarinic receptor normally activates delayed rectifier potassium channels in the atria, thus increased Gαq activity is thought to result in an altered potassium flux, a decreased refractory period, increased chance of current re-entry and inappropriate contraction. Interactions RGS2 has been shown to interact with PRKG1 and ADCY5. References Further reading