Paired amphipathic helix protein Sin3a is a protein that in humans is encoded by the SIN3A gene. Function The protein encoded by this gene is a transcriptional regulatory protein. It contains paired amphipathic helix (PAH) domains, which are important for protein-protein interactions and may mediate repression by the Mad-Max complex. Interactions SIN3A has been shown to interact with: CABIN1 HBP1, HDAC1, HDAC9, Histone deacetylase 2, Host cell factor C1, IKZF1, ING1, KLF11, MNT, MXD1, Methyl-CpG-binding domain protein 2, Nuclear receptor co-repressor 2, OGT, PHF12, Promyelocytic leukemia protein, RBBP4, RBBP7, SAP130, SAP30, SMARCA2, SMARCA4, SMARCC1, SUDS3, TAL1, and Zinc finger and BTB domain-containing protein 16. See also Transcription coregulator References Further reading External links Gene expression Transcription coregulators