style="background:#fbb" | 6 || April 14 || Pirates || 1–3 (10) || Cecilio Guante (1–0) || Steve Bedrosian (1–1) || Jim Winn (1) || 16,200 || 3–3 |- style="background:#bbb" | – || April 15 || Pirates || colspan=6 | Postponed (rain); Makeup: August 15 as a traditional double-header |- style="background:#bbb" | – || April 16 || Pirates || colspan=6 | Postponed (rain); Makeup: August 16 as a traditional double-header |- style="background:#fbb" | 7 || April 18 || @ Mets || 2–5 || Ron Darling (1–0) || Steve Carlton (0–2) || Jesse Orosco (2) || 26,906 || 3–4 |- style="background:#fbb" | 8 || April 19 || @ Mets || 2–3 || Dwight Gooden (2–0) || Shane Rawley (1–1) || None || 38,333 || 3–5 |- style="background:#fbb" | 9 || April 20 || @ Mets || 0–8 || Sid Fernandez (1–0) || Kevin Gross (0–2) || None || 41,848 || 3–6 |- style="background:#fbb" | 10 || April 22 || @ Expos || 2–8 || Andy McGaffigan (1–0) || Charles Hudson (1–1) || Tim Burke (2) || 4,276 || 3–7 |- style="background:#bfb" | 11 || April 23 || @ Expos || 5–4 || Steve Carlton (1–2) || Joe Hesketh (0–3) || Steve Bedrosian (1) || 6,293 || 4–7 |- style="background:#bfb" | 12 || April 24 || @ Pirates || 4–2 || Shane Rawley (2–1) || Rick Rhoden (2–1) || None || 14,622 || 5–7 |- style="background:#bfb" | 13 || April 25 || @ Pirates || 6–3 || Kevin Gross (1–2) || Rick Reuschel (2–2) || Steve Bedrosian (2) || 11,847 || 6–7 |- style="background:#bfb" | 14 || April 26 || @ Pirates || 6–5 || Charles Hudson (2–1) || Larry McWilliams (0–2) || Steve Bedrosian (3) || 16,373 || 7–7 |- style="background:#fbb" | 15 || April 27 || @ Pirates || 5–13 || Mike Bielecki (1–0) || Steve Carlton (1–3) || Bob Walk (1) || 17,218 || 7–8 |- style="background:#bfb" | 16 || April 29 || Astros || 12–4 || Shane Rawley (3–1) || Nolan Ryan (3–3) || None || 16,313 || 8–8 |- style="background:#fbb" | 17 || April 30 || Astros || 0–1 || Mike Scott (3–2) || Kevin Gross (1–3) || Dave Smith (7) || 17,134 || 8–9 |- |- style="background:#fbb" | 18 || May 2 || Braves || 1–7 || David Palmer (2–1) || Steve Carlton (1–4) || None || 20,237 || 8–10 |- style="background:#fbb" | 19 || May 3