|| 42–56 |- style="background:#fbb" | 99 || July 30 || @ Giants || 2–7 || Mike McCormick (10–8) || Robin Roberts (9–10) || None || 10,114 || 42–57 |- style="background:#fbb" | 100 || July 31 || @ Dodgers || 4–5 || Don Drysdale (14–6) || Gene Conley (9–7) || None || 21,900 || 42–58 |- style="background:#fbb" | 101 || August 1 || @ Dodgers || 3–5 || Clem Labine (5–8) || Jim Owens (7–9) || None || 30,536 || 42–59 |- style="background:#fbb" | 102 || August 2 || @ Dodgers || 3–4 || Larry Sherry (2–2) || Don Cardwell (5–7) || None || 10,201 || 42–60 |- style="background:#bbcaff;" | – || August 3 ||colspan=7 |1959 Major League Baseball All-Star Game at the Los Angeles Memorial Coliseum in Los Angeles |- style="background:#bfb" | 103 || August 4 || @ Cubs || 2–1 || Robin Roberts (10–10) || Bob Anderson (7–8) || None || 8,348 || 43–60 |- style="background:#bfb" | 104 || August 5 || @ Cubs || 6–4 || Gene Conley (10–7) || Bill Henry (6–5) || Taylor Phillips (1) || 9,128 || 44–60 |- style="background:#fbb" | 105 || August 6 || @ Cubs || 2–4 || Don Elston (6–4) || Humberto Robinson (2–2) || None || 6,477 || 44–61 |- style="background:#fbb" | 106 || August 7 || @ Cardinals || 1–3 || Lindy McDaniel (11–10) || Rubén Gómez (1–8) || None || 8,764 || 44–62 |- style="background:#fbb" | 107 || August 8 || @ Cardinals || 3–4 || Bob Miller (1–0) || Robin Roberts (10–11) || None || || 44–63 |- style="background:#fbb" | 108 || August 8 || @ Cardinals || 4–5 || Lindy McDaniel (12–10) || Turk Farrell (1–3) || None || 11,296 || 44–64 |- style="background:#bfb" | 109 || August 9 || @ Cardinals || 8–3 || Gene Conley (11–7) || Ernie Broglio (6–8) || None || || 45–64 |- style="background:#bfb" | 110 || August 9 || @ Cardinals || 4–2 || Jim Owens (8–9) || Marshall Bridges (4–3) || Turk Farrell (4) || 20,129 || 46–64 |- style="background:#bfb" | 111 || August 11 || Pirates || 6–4 || Don Cardwell (6–7) || Bob Friend (4–15) || Turk Farrell (5) || 12,127 || 47–64 |- style="background:#fbb" | 112 || August 12 || Pirates || 2–6 || Harvey Haddix (9–9) || Robin Roberts (10–12) || None || 11,163 || 47–65 |- style="background:#fbb" | 113 || August 14 || Reds