May 13 || @ Dodgers || 3–6 || Vito Tamulis (1–0) || Ike Pearson (1–2) || None || 5,337 || 6–11 |- style="background:#bfb" | 18 || May 14 || Cardinals || 4–0 || Hugh Mulcahy (3–1) || Ernie White (1–1) || None || 1,500 || 7–11 |- style="background:#bfb" | 19 || May 15 || Cardinals || 6–3 || Kirby Higbe (3–3) || Gene Lillard (0–1) || None || 2,000 || 8–11 |- style="background:#bbb" | – || May 16 || Cardinals || colspan=6 | Postponed (rain); Makeup: July 25 |- style="background:#fbb" | 20 || May 17 || Reds || 2–7 || Whitey Moore (1–0) || Lloyd Brown (0–3) || Elmer Riddle (2) || 1,731 || 8–12 |- style="background:#bfb" | 21 || May 18 || Reds || 8–3 || Hugh Mulcahy (4–1) || Paul Derringer (3–3) || None || 8,000 || 9–12 |- style="background:#bfb" | 22 || May 19 || Pirates || 6–5 || Si Johnson (1–1) || Rip Sewell (0–1) || None || 8,981 || 10–12 |- style="background:#bfb" | 23 || May 20 || Pirates || 8–7 || Lefty Hoerst (1–0) || Dick Lanahan (0–2) || None || 1,000 || 11–12 |- style="background:#bbb" | – || May 21 || Pirates || colspan=6 | Postponed (rain); Makeup: June 26 as a traditional double-header |- style="background:#bbb" | – || May 22 || Cubs || colspan=6 | Postponed (rain); Makeup: May 23 |- style="background:#fbb" | 24 || May 23 || Cubs || 3–4 || Vern Olsen (2–1) || Hugh Mulcahy (4–2) || Vance Page (1) || 7,801 || 11–13 |- style="background:#bbb" | – || May 24 || Dodgers || colspan=6 | Postponed (rain, cold, threatening weather); Makeup: September 5 |- style="background:#bbb" | – || May 25 || Dodgers || colspan=6 | Postponed (rain); Makeup: September 6 as a traditional double-header |- style="background:#fbb" | 25 || May 26 || Dodgers || 1–2 || Vito Tamulis (2–0) || Kirby Higbe (3–4) || None || 3,281 || 11–14 |- style="background:#fbb" | 26 || May 27 || @ Dodgers || 0–6 || Whit Wyatt (4–2) || Lefty Smoll (1–3) || None || 3,578 || 11–15 |- style="background:#fbb" | 27 || May 28 || @ Dodgers || 2–4 || Freddie Fitzsimmons (4–0) || Hugh Mulcahy (4–3) || None || 28,918 || 11–16 |- style="background:#fbb" | 28 || May 29 || @ Bees || 1–3 || Dick Errickson (2–0) || Boom-Boom Beck (0–1) || None || 1,143 || 11–17 |-