In enzymology, a glycine dehydrogenase () is an enzyme that catalyzes the chemical reaction glycine + H2O + NAD+ glyoxylate + NH3 + NADH + H+ The 3 substrates of this enzyme are glycine, H2O, and NAD+, whereas its 4 products are glyoxylate, NH3, NADH, and H+. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH2 group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is glycine:NAD+ oxidoreductase (deaminating). This should not be confused with: the glycine dehydrogenase (decarboxylating), which is another name for the Glycine cleavage system P-protein (). or the glycine dehydroganse (cyanide forming)(). or the glycine dehydrogenase (cytochrome) (). References EC 1.4.1 NADH-dependent enzymes Enzymes of unknown structure