In enzymology, a vanillin dehydrogenase () is an enzyme that catalyzes the chemical reaction + NAD+ + H2O + NADH + H+ The 3 substrates of this enzyme are vanillin, NAD+, and H2O, whereas its 3 products are vanillate, NADH, and H+. This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is vanillin:NAD+ oxidoreductase. This enzyme participates in 2,4-dichlorobenzoate degradation. References EC 1.2.1 NADH-dependent enzymes Enzymes of unknown structure