Science and technology in Colombia refers to the development of scientific research and technological innovation in Colombia, and how these in turn affect Colombian society, politics, and culture. Colciencias is a government agency that supports fundamental and applied research in Colombia. Research groups in science and technology Colombia has more than 3,950 research groups in science and technology. Colombia was ranked 68th in the Global Innovation Index in 2020, down from 67th in 2019. iNNpulsa, a government body that promotes entrepreneurship and innovation in the country, provides grants to startups, in addition to other services it and institutions provide. Co-working spaces have arisen to serve as communities for startups large and small. Organizations such as the Corporation for Biological Research (CIB) for the support of young people interested in scientific work has been successfully developed in Colombia. The International Center for Tropical Agriculture based in Colombia investigates the increasing challenge of global warming and food security. Some leading Colombian scientists are Joseph M. Tohme, researcher recognized for his work on the genetic diversity of food, Manuel Elkin Patarroyo who is known for his groundbreaking work on synthetic vaccines for malaria, Francisco Lopera who discovered the "Paisa Mutation" or a type of early-onset Alzheimer's, Rodolfo Llinás known for his study of the intrinsic neurons properties and the theory of a syndrome that had changed the way of understanding the functioning of the brain, Jairo Quiroga Puello recognized for his studies on the characterization of synthetic substances which can be used to fight fungus, tumors, tuberculosis and even some viruses and Ángela Restrepo who established accurate diagnoses and treatments to combat the effects of a disease caused by the Paracoccidioides brasiliensis, among other scientists. Aerospace Colombia is seventh of the eight Latin American countries to have satellites in orbit. On April 7, 2007 Libertad I (CubeSat), was sent from Baikonur cosmodrome, to orbit around the planet offering telemetry information and as a research purpose. It represents a milestone in the history of Colombia and the first step of the Colombian aerospace development. Aeronautic With the establishment in Colombia of the Aeroleaver factory more than 50 years ago, and with a joint effort of the government, it was managed to develop the first Colombian airship, completely with Colombian technology and elaborated in the country, the "Sparrowhawk". At the moment Armed Forces of Colombia uses some of these airplanes, and others are of commercial