|- style="background:#bfb" | 27 || May 12 || Cardinals || 3–2 || Lefty Hoerst (3–2) || Max Lanier (2–2) || None || 2,000 || 8–19 |- style="background:#fbb" | 28 || May 13 || Cardinals || 1–9 || Lon Warneke (2–2) || Si Johnson (1–3) || None || 5,000 || 8–20 |- style="background:#fbb" | 29 || May 14 || Cubs || 3–5 || Bill Lee (5–1) || Rube Melton (2–3) || None || 2,000 || 8–21 |- style="background:#fbb" | 30 || May 15 || Cubs || 1–2 || Claude Passeau (4–3) || Tommy Hughes (1–5) || None || 1,500 || 8–22 |- style="background:#bbb" | – || May 16 || Cubs || colspan=6 | Postponed (inclement weather); Makeup: June 25 |- style="background:#fbb" | 31 || May 17 (1) || Pirates || 2–7 || Luke Hamlin (2–1) || Lefty Hoerst (3–3) || None || see 2nd game || 8–23 |- style="background:#bfb" | 32 || May 17 (2) || Pirates || 5–4 (11) || Rube Melton (3–3) || Bob Klinger (2–1) || None || 10,079 || 9–23 |- style="background:#bfb" | 33 || May 19 || Pirates || 5–4 || Johnny Podgajny (2–3) || Max Butcher (4–3) || Lefty Hoerst (1) || 3,366 || 10–23 |- style="background:#fbb" | 34 || May 20 || Reds || 3–10 || Ray Starr (4–1) || Tommy Hughes (1–6) || None || 1,145 || 10–24 |- style="background:#bfb" | 35 || May 21 || Reds || 3–2 || Si Johnson (2–3) || Paul Derringer (0–2) || None || 1,068 || 11–24 |- style="background:#fbb" | 36 || May 22 || Braves || 7–10 || Lou Tost (3–2) || Earl Naylor (0–2) || Johnny Sain (2) || 4,007 || 11–25 |- style="background:#bfb" | 37 || May 23 || Braves || 6–5 || Si Johnson (3–3) || Manny Salvo (1–2) || None || 1,663 || 12–25 |- style="background:#bfb" | 38 || May 24 (1) || Braves || 3–2 (11) || Sam Nahem (1–0) || Jim Tobin (5–5) || None || see 2nd game || 13–25 |- style="background:#fbb" | 39 || May 24 (2) || Braves || 3–6 || Dick Errickson (2–0) || Earl Naylor (0–3) || Johnny Sain (3) || 10,965 || 13–26 |- style="background:#fbb" | 40 || May 25 || @ Dodgers || 0–3 || Curt Davis (6–1) || Lefty Hoerst (3–4) || None || 9,572 || 13–27 |- style="background:#fbb" | 41 || May 27 || Giants || 2–6 || Bob Carpenter (4–2)