|| Jim Bunning (1–2) || Don Shaw (3) || 5,093 || 4–3 |- style="background:#bfb" | 8 || April 22 || @ Mets || 4–3 || Larry Jackson (2–0) || Bob Shaw (0–2) || None || 15,032 || 5–3 |- style="background:#bfb" | 9 || April 23 (1) || @ Mets || 10–6 || Grant Jackson (1–0) || Don Shaw (0–1) || None || see 2nd game || 6–3 |- style="background:#bfb" | 10 || April 23 (2) || @ Mets || 3–1 || Dick Ellsworth (1–0) || Bill Denehy (0–2) || None || 38,081 || 7–3 |- style="background:#fbb" | 11 || April 25 || @ Pirates || 3–7 || Billy O'Dell (1–0) || Jim Bunning (1–3) || None || 5,585 || 7–4 |- style="background:#bbb" | – || April 26 || @ Pirates || colspan=6 | Postponed (rain); Makeup: August 31 |- style="background:#fbb" | 12 || April 27 || @ Pirates || 4–5 || Pete Mikkelsen (1–0) || Dick Hall (0–1) || Bill Short (1) || 4,979 || 7–5 |- style="background:#fbb" | 13 || April 28 || @ Braves || 8–9 || Clay Carroll (2–2) || Dick Hall (0–2) || None || 12,921 || 7–6 |- style="background:#fbb" | 14 || April 29 || @ Braves || 2–3 || Pat Jarvis (2–0) || Chris Short (1–2) || Phil Niekro (3) || 12,200 || 7–7 |- style="background:#bfb" | 15 || April 30 (1) || @ Braves || 6–4 || Grant Jackson (2–0) || Clay Carroll (2–3) || Dick Hall (1) || see 2nd game || 8–7 |- style="background:#fbb" | 16 || April 30 (2) || @ Braves || 3–6 || Bob Bruce (1–0) || Rick Wise (1–1) || Phil Niekro (4) || 27,644 || 8–8 |- |- style="background:#fbb" | 17 || May 2 || Astros || 3–10 || Mike Cuellar (2–1) || Larry Jackson (2–1) || None || 4,568 || 8–9 |- style="background:#bfb" | 18 || May 3 || Astros || 1–0 || Chris Short (2–2) || Larry Dierker (2–2) || None || 4,428 || 9–9 |- style="background:#fbb" | 19 || May 4 || Astros || 1–4 || Turk Farrell (1–0) || Dick Ellsworth (1–1) || Carroll Sembera (1) || 3,591 || 9–10 |- style="background:#bfb" | 20 || May 5 || Dodgers || 3–1 || Jim Bunning (2–3) || Jim Brewer (0–1) || Chris Short (1) || 12,805 || 10–10 |- style="background:#bbb" | – || May 6 || Dodgers || colspan=6 | Postponed (rain); Makeup: