Debrisoquine is a derivative of guanidine. It is an antihypertensive drug similar to guanethidine. Debrisoquine is frequently used for phenotyping the CYP2D6 enzyme, a drug-metabolizing enzyme. See also Isoquinoline#Applications of derivatives The guanidine part of the molecule also appears in guanoxan and guanadrel. The 7-bromo analog of Debrisoquine is called Guanisoquin. References Adrenergic release inhibitors Antihypertensive agents Guanidines Tetrahydroisoquinolines