35,783 || 28–35 |- style="background:#fbb" | 64 || June 14 || Orioles || 3–7 || B. J. Ryan (1–0) || Ricky Bottalico (0–3) || None || 16,888 || 28–36 |- style="background:#bfb" | 65 || June 15 || Orioles || 4–3 (10) || Rhéal Cormier (3–4) || Buddy Groom (2–2) || None || 20,634 || 29–36 |- style="background:#fbb" | 66 || June 16 || Orioles || 2–4 || Travis Driskill (4–0) || Terry Adams (3–5) || Jorge Julio (13) || 41,079 || 29–37 |- style="background:#fbb" | 67 || June 18 || White Sox || 3–6 (12) || Antonio Osuna (4–1) || David Coggin (0–2) || Rocky Biddle (1) || 17,424 || 29–38 |- style="background:#bfb" | 68 || June 19 || White Sox || 4–3 || Dan Plesac (2–2) || Rocky Biddle (1–1) || None || 21,905 || 30–38 |- style="background:#fbb" | 69 || June 20 || White Sox || 1–6 || Mark Buehrle (10–5) || Robert Person (2–4) || None || 22,132 || 30–39 |- style="background:#bfb" | 70 || June 21 || Twins || 3–0 || Brandon Duckworth (4–4) || Kyle Lohse (6–5) || José Mesa (19) || 17,039 || 31–39 |- style="background:#fbb" | 71 || June 22 || Twins || 1–4 (11) || LaTroy Hawkins (2–0) || Dan Plesac (2–3) || Eddie Guardado (21) || 18,759 || 31–40 |- style="background:#fbb" | 72 || June 23 || Twins || 1–5 || Tony Fiore (6–2) || Randy Wolf (3–6) || None || 38,158 || 31–41 |- style="background:#bfb" | 73 || June 24 || @ Marlins || 15–4 || Vicente Padilla (10–4) || Julián Tavárez (5–4) || None || 5,465 || 32–41 |- style="background:#bfb" | 74 || June 25 || @ Marlins || 7–6 (11) || José Mesa (2–4) || Vic Darensbourg (1–2) || Dan Plesac (1) || 5,355 || 33–41 |- style="background:#fbb" | 75 || June 26 || @ Marlins || 2–6 || Michael Tejera (3–1) || Brandon Duckworth (4–5) || None || 6,503 || 33–42 |- style="background:#bfb" | 76 || June 27 || @ Marlins || 7–3 || Terry Adams (4–5) || Kevin Olsen (0–5) || None || 6,079 || 34–42 |- style="background:#bfb" | 77 || June 28 || @ Orioles || 6–2 || Randy Wolf (4–6) || Travis Driskill (5–1) || None || 48,937 || 35–42 |- style="background:#fbb" | 78 || June 29 || @ Orioles || 1–11 || Jason Johnson (3–5) || Vicente Padilla (10–5) || None || 48,692