| – || July 1 || @ Cardinals || colspan=6 | Game cancelled: players' strike |- style="background:#bbb" | – || July 2 || @ Cardinals || colspan=6 | Game cancelled: players' strike |- style="background:#bbb" | – || July 3 || Expos || colspan=6 | Game cancelled: players' strike |- style="background:#bbb" | – || July 4 || Expos || colspan=6 | Game cancelled: players' strike |- style="background:#bbb" | – || July 5 || Expos || colspan=6 | Game cancelled: players' strike |- style="background:#bbb" | – || July 7 || @ Pirates || colspan=6 | Game cancelled: players' strike |- style="background:#bbb" | – || July 8 || @ Pirates || colspan=6 | Game cancelled: players' strike |- style="background:#bbb" | – || July 9 || @ Pirates || colspan=6 | Game cancelled: players' strike |- style="background:#bbb" | – || July 10 || Mets || colspan=6 | Game cancelled: players' strike |- style="background:#bbb" | – || July 11 (1) || Mets || colspan=6 | Game cancelled: players' strike |- style="background:#bbb" | – || July 11 (2) || Mets || colspan=6 | Game cancelled: players' strike |- style="background:#bbb" | – || July 12 || Mets || colspan=6 | Game cancelled: players' strike |- style="background:#bbb" | – || July 14 || colspan=7 | 1981 Major League Baseball All-Star Game at Cleveland Stadium in Cleveland Cancelled (players' strike), then postponed to August 9|- style="background:#bbb" | – || July 16 || Giants || colspan=6 | Game cancelled: players' strike|- style="background:#bbb" | – || July 17 || Giants || colspan=6 | Game cancelled: players' strike|- style="background:#bbb" | – || July 18 || Dodgers || colspan=6 | Game cancelled: players' strike|- style="background:#bbb" | – || July 19 || Dodgers || colspan=6 | Game cancelled: players' strike|- style="background:#bbb" | – || July 20 || Dodgers || colspan=6 | Game cancelled: players' strike|- style="background:#bbb" | – || July 21 || Padres || colspan=6 | Game cancelled: players' strike|- style="background:#bbb" | – || July 22 || Padres || colspan=6 | Game cancelled: players' strike|- style="background:#bbb" | – || July 23 || Padres || colspan=6 | Game cancelled: players' strike|- style="background:#bbb" | – || July 24 || @ Giants || colspan=6 | Game cancelled: players' strike|- style="background:#bbb" | – || July 25 || @ Giants || colspan=6 | Game cancelled: players' strike|- style="background:#bbb" | – || July 26 || @ Giants || colspan=6 | Game cancelled: players' strike|- style="background:#bbb" | – || July 27