colspan=6 | Postponed (rain); Makeup: April 10 |- style="background:#bfb" | 4 || April 10 || Pirates || 7–3 || Dick Ruthven (1–0) || Enrique Romo (0–2) || None || 48,235 || 1–2 |- style="background:#bfb" | 5 || April 11 || Pirates || 5–4 || Steve Carlton (1–1) || Bert Blyleven (0–1) || None || 26,281 || 2–2 |- style="background:#fbb" | 6 || April 12 || @ Mets || 2–3 || Pat Zachry (2–0) || Randy Lerch (0–1) || None || 8,719 || 2–3 |- style="background:#bbb" | – || April 14 || @ Mets || colspan=6 | Postponed (rain); Makeup: August 2 as a traditional double-header |- style="background:#bfb" | 7 || April 15 (1) || @ Mets || 3–2 || Dick Ruthven (2–0) || Craig Swan (1–1) || Tug McGraw (1) || see 2nd game || 3–3 |- style="background:#bfb" | 8 || April 15 (2) || @ Mets || 6–3 || Nino Espinosa (1–0) || Neil Allen (0–1) || Ron Reed (1) || 18,401 || 4–3 |- style="background:#bbb" | – || April 16 || @ Pirates || colspan=6 | Postponed (rain); Makeup: August 3 as a traditional double-header |- style="background:#bfb" | 9 || April 17 || @ Pirates || 13–2 || Steve Carlton (2–1) || Bert Blyleven (0–2) || None || 7,739 || 5–3 |- style="background:#bfb" | 10 || April 18 || @ Pirates || 3–2 || Randy Lerch (1–1) || Don Robinson (1–1) || None || 12,195 || 6–3 |- style="background:#bfb" | 11 || April 20 || Mets || 8–0 || Dick Ruthven (3–0) || Craig Swan (1–2) || None || 33,253 || 7–3 |- style="background:#bfb" | 12 || April 21 || Mets || 3–0 || Nino Espinosa (2–0) || Neil Allen (0–2) || Tug McGraw (2) || 31,851 || 8–3 |- style="background:#fbb" | 13 || April 22 || Mets || 2–4 || Jesse Orosco (1–0) || Steve Carlton (2–2) || Skip Lockwood (2) || 35,020 || 8–4 |- style="background:#bfb" | 14 || April 23 || Dodgers || 4–3 (10) || Tug McGraw (1–0) || Lance Rautzhan (0–2) || None || 32,826 || 9–4 |- style="background:#bfb" | 15 || April 24 || Dodgers || 7–6 (10) || Ron Reed (1–1) || Jerry Reuss (1–2) || None || 31,140 || 10–4 |- style="background:#bfb" | 16 || April 25 || Dodgers || 5–4 || Ron Reed (2–1) || Rick Sutcliffe (1–1) || None || 34,303 || 11–4 |- style="background:#bfb" | 17 ||