(b. 1461) December 2 – Muhammad Shaybani, Khan of Bukhara (b. 1451) December 14 – Friedrich of Saxony (b. 1473) December 31 – Bianca Maria Sforza, Holy Roman Empress (b. 1472) date unknown Agüeybaná, Taino chief Giovanna d'Aragona, Duchess of Amalfi, Italian regent (b. 1478) Ambrogio Calepino, Italian lexicographer (b. 1450) Giorgione, Italian painter (b. c. 1477) Mandukhai Khatun, Mongolian queen References