The first black slaves arrive in Colombia. The Spanish conquest of Yucatán begins. Erasmus publishes his most famous work, The Praise of Folly (Laus stultitiae). Births January 1 – Henry, Duke of Cornwall, eldest son of Henry VIII of England April 2 – Ashikaga Yoshiharu, Japanese shōgun (d. 1550) April 5 – John III, Count of Nassau-Saarbrücken, German noble (d. 1574) June 4 – Honorat II of Savoy, French Navy admiral (d. 1580) June 6 – Jakob Schegk, German physician (d. 1587) June 18 – Bartolomeo Ammannati, Florentine architect and sculptor (d. 1592) July 9 – Dorothea of Saxe-Lauenburg, consort of Christian III from 1525, and Queen of Denmark and Norway (d. 1571) July 30 – Giorgio Vasari, Italian painter and architect (d. 1574) August 24 – Jean Bauhin, French physician (d. 1582) September 28 – Matsudaira Kiyoyasu, Japanese daimyo (d. 1535) September 29 – Michael Servetus, Spanish theologian (d. 1553) October 22 – Erasmus Reinhold, German astronomer and mathematician (d. 1553) November 8 – Paul Eber, German Lutheran theologian (d. 1569) November 15 – Johannes Secundus, Dutch poet (d. 1536) December 5 – Maldev Rathore, ruler of Marwar (d. 1562) date unknown Amato Lusitano, Portuguese Jewish physician (d. 1568) Birgitte Gøye, Danish county administrator, lady in waiting, landholder and educator (d. 1574) Kimotsuki Kanetsugu, Japanese samurai and warlord (d. 1566) Luís de Velasco, Spanish viceroy of New Spain (d. 1564) Nicola Vicentino, Italian music theorist and composer (d. 1576) Nicholas Bobadilla, one of the first Spanish Jesuits (d. 1590) Pierre Viret, Swiss reformed theologian (d. 1571) Gaspar Cervantes de Gaeta, Spanish cardinal (d. 1575) Deaths January 9 – Demetrios Chalkokondyles, Greek classical scholar (b. 1424) January 20 – Oliviero Carafa, Italian Catholic cardinal (b. 1430) February 22 – Henry, Duke of Cornwall, eldest son of Henry VIII of England April 1 – Francis of Denmark, Danish prince (b. 1497) April 2 – Bernard VII, Lord of Lippe, German nobleman (b. 1428) June 3 – Ahmad ibn Abi Jum'ah, North African Islamic scholar, author of the Oran fatwa June 13 – Hedwig, Abbess of Quedlinburg, Princess-Abbess of Quedlinburg (b. 1445) July 2 – Şahkulu, leader of the Şahkulu Rebellion July 6 – Adolf III of Nassau-Wiesbaden-Idstein, Germany noble (b. 1443) July 12 – Albert I, Duke of Münsterberg-Oels, Count of Kladsko (b. 1468) August 2 – Andrew Barton, Scottish naval leader (b. c. 1466) September 6 Ashikaga Yoshizumi, Japanese shogun