the structural equations is unknown, an instrumental variable can still be defined through the equations: where and are two arbitrary functions and is independent of . Unlike linear models, however, measurements of and do not allow for the identification of the average causal effect of on , denoted ACE Balke and Pearl [1997] derived tight bounds on ACE and showed that these can provide valuable information on the sign and size of ACE. In linear analysis, there is no test to falsify the assumption the is instrumental relative to the pair . This is not the case when is discrete. Pearl (2000) has shown that, for all and , the following constraint, called "Instrumental Inequality" must hold whenever satisfies the two equations above: Interpretation under treatment effect heterogeneity The exposition above assumes that the causal effect of interest does not vary across observations, that is, that is a constant. Generally, different subjects will respond in different ways to changes in the "treatment" x. When this possibility is recognized, the average effect in the population of a change in x on y may differ from the effect in a given subpopulation. For example, the average effect of a job training program may substantially differ across the group of people who actually receive the training and the group which chooses not to receive training. For these reasons, IV methods invoke implicit assumptions on behavioral response, or more generally assumptions over the correlation between the response to treatment and propensity to receive treatment. The standard IV estimator can recover local average treatment effects (LATE) rather than average treatment effects (ATE). Imbens and Angrist (1994) demonstrate that the linear IV estimate can be interpreted under weak conditions as a weighted average of local average treatment effects, where the weights depend on the elasticity of the endogenous regressor to changes in the instrumental variables. Roughly, that means that the effect of a variable is only revealed for the subpopulations affected by the observed changes in the instruments, and that subpopulations which respond most to changes in the instruments will have the largest effects on the magnitude of the IV estimate. For example, if a researcher uses presence of a land-grant college as an instrument for college education in an earnings regression, she identifies the effect of college on earnings in the subpopulation which would obtain a college degree if a college is present but which