That level of complexity is one of the primary impediments to the growth of combination therapy in oncology. T has recently highlighted combination therapy as a top research priority in oncology. Bacterial infections Combination therapy with two or more antibiotics are often used in an effort to treat multi-drug resistant Gram-negative bacteria. Contrast to monotherapy Monotherapy, or the use of a single therapy, can be applied to any therapeutic approach, but it is most commonly used to describe the use of a single medication. Normally, monotherapy is selected because a single medication is adequate to treat the medical condition. However, monotherapies may also be used because of unwanted side effects or dangerous drug interactions. See also Polypill, a medication which contains a combination of multiple active ingredients Combination drug References External links Drug combination database. covers information on more than 1300 drug combinations in either clinical use or different testing stages. Perturbation biology method for the discovery of anti-resistance drug combinations with network pharmacology. Medical treatments Medical terminology Pharmacology