Argentinian Leonardo Mayer in three sets, despite saving 21 of 24 break points in the match. At the French Open, Baghdatis was beaten by Britain's Andy Murray in the third round in four sets. He suffered a surprisingly poor run in the 2010 grass-court season. He went out in the first rounds in all three grass court tournaments he entered by Philipp Petzschner in Halle, Peter Luczak in s-Hertogenbosch, and Lukáš Lacko at Wimbledon. It was the worst showing he had had in Wimbledon, and even more disappointing as he had a good history record in the past few years there. However, a reshuffle behind the scenes after the grass court season has resulted in Baghdatis once again working with Guillaume Perye. Since then, he reached the quarterfinals at the Farmers Classic tournament in Los Angeles, where he lost to Janko Tipsarević for the first time in their third meeting, and reached the final at the Legg Mason Tennis Classic in Washington, where he lost to in-form David Nalbandian, who marked his thorough comeback on the tour there. Baghdatis was ousted in the opening round at the Rogers Cup in Toronto, losing to Jérémy Chardy in three sets. At the Cincinnati Masters, he found decent form. In the first round, he beat Marin Čilić for the first time. In the second round, he toughed out a three-sets victory over Brazilian Thomaz Bellucci, followed by a two-sets victory in the third round against Tomáš Berdych. In the quarterfinals, after six successive losses against the Spaniard, he finally defeated Rafael Nadal for the first time in his career. It was his second win over a world No. 1 that year, having earlier defeated then-No. 1 Roger Federer at the Indian Wells Masters. Oddly, he defeated a world-number-one player on his seventh attempt again. As he stated back in March 2010 after beating Federer, "Seven is my lucky number." For only the second time, he made the semifinals of a Masters 1000 tournament, but here he could not beat Roger Federer again, as he succumbed to his in-form opponent in two sets. Just before his campaign at the US Open, he made an appearance at the last tune-up tournament, the 2010 Pilot Pen Tennis in New Haven, Connecticut. Baghdatis had a chance to win the year's US Open Series if he won this tournament. Appearing as the top seeded player, he beat Igor