mint has been a problem for consumers. To protect the reputation of their produce, the Italian government introduced tight controls, including testing and certificates of purity. The Stazione Sperimentale per le Industrie delle Essenze e dei Derivati dagli Agrumi (Experimental Station for Essential Oil and Citrus By-Products) located in Reggio di Calabria, is the quality control body for the essential oil Bergamotto di Reggio Calabria DOP. During World War II, Italy was unable to export to countries such as the Allied powers. Rival products from Brazil and Mexico came on to the market as a substitute, but these were produced from other citrus fruits such as sweet lime. Uses Tea and other uses An essence extracted from the aromatic skin of this sour fruit is used to flavour Earl Grey and Lady Grey teas, as well as confectionery (including Turkish delight). Bergamot is one of the most common "casings" (flavorings) added to Swedish snus, a form of smokeless tobacco product. Fragrance Bergamot oil is one of the most commonly used ingredients in perfumery. It is prized for its ability to combine with an array of scents to form a bouquet of aromas that complement each other. Bergamot is a major component of the original composed by Jean-Marie Farina at the beginning of the 18th century in Germany. The first use of bergamot oil as a fragrance ingredient was recorded in 1714, and can be found in the Farina Archive in Cologne. However, much "Bergamot oil" is today derived instead from eau de Cologne mint, also known as bergamot mint, which is a variety of water mint and is unrelated to citrus. Toxicology In several patch test studies, application of some sources of bergamot oil directly to the skin of guinea pigs was shown to have a concentration-dependent phototoxic effect of increasing redness after exposure to ultraviolet light (due to the chemical bergapten, and possibly also citropten, bergamottin, geranial, and neral). This is a property shared by many other citrus fruits and other members of Rutaceae, including rue. Skin effects Used in cosmetics and perfume products, bergamot may cause skin irritation. In the past, psoralen extracted from bergamot oil was used in tanning accelerators and sunscreens. Known to be photocarcinogenic since 1959, the substances nonetheless were used in tanning activators until 1995, contributing to many cases of melanoma and death. Research As of 2017, clinical research conducted on bergamot oil has