That deployment also saw her on patrol in the Taiwan Strait during the American show of force over the Quemoy and Matsu bombardment by the Chinese communists. The remainder of her deployments were more routine in nature consisting of plane guard duty with TF 77, port visits, training exercises, and periods of time with the Taiwan Strait patrol. When not in the Orient, she conducted type training, upkeep, and periodic overhauls on the west coast. The warship departed San Diego on 5 August 1964 to begin her 11th deployment to the Far East. Four days before, the Gulf of Tonkin incident occurred, signaling a stepped-up American involvement in the strife in South Vietnam. That involvement dictated the nature of Wedderburn's 7th Fleet assignments for the remainder of her active career. During the fall of 1964, she operated off the Vietnamese coast as plane guard and escort for TF 77, duplicating her service during World War II and the Korean War. She departed the newly established combat zone in November for a SEATO weapons demonstration and then put into Subic Bay in the Philippines for upkeep. 1965 – 1969 After Christmas liberty at Yokosuka, Japan, she returned to active operations in the South China Sea in January 1965. At the conclusion of that duty, late in the month, she set course for home, arriving in San Diego on 6 February. She spent the remainder of 1965 in the eastern Pacific. After a month of post-deployment stand-down followed by four weeks of local operations out of San Diego, she entered the Long Beach Naval Shipyard for a month-long availability. In June and July, she embarked NROTC midshipmen for their summer cruise, during which she visited San Francisco and the islands of Kauai and Oahu in Hawaii. Returning to San Diego on 4 August, the warship conducted three weeks of repairs and then resumed training operations which continued until she began preparations for another Far Eastern cruise in November. On 7 January 1966, Wedderburn departed San Diego in company with Worden (DLG-18), Richard B. Anderson (DD-786), and Bausell (DD-845). After stops at Oahu, Midway, and Guam, she arrived in Subic Bay on 28 January. On 1 February, she headed for the South China Sea where she became a unit of TG 77.5 and served as escort and plane guard for the carriers until 28 February. Following a brief return to Subic Bay, she