Masters but lost to Rita Kuti-Kis in the first round of the main draw. She received a wildcard for the Miami Masters, but lost in the first round. Hantuchová played three Fed Cup matches for Slovakia in April, and then in the German Open in May, where she lost in the second qualifying round to Francesca Schiavone. At the Rome Masters, Hantuchová lost in the singles to eventual finalist Amélie Mauresmo in the third round. She also competed in the doubles with Nagyová. They beat Kerry-Anne Guse and Alicia Molik in the first round, Martina Navratilova and Arantxa Sánchez Vicario in the second round, Mary Pierce and Ai Sugiyama in the quarterfinal and lost to Paola Suárez and Patricia Tarabini in the semifinal. Hantuchová's form saw her qualify automatically for the French Open, beating Alexandra Stevenson in the first round and losing to eighth seed Conchita Martínez in the second round. She again teamed up with Nagyová in the doubles, reaching the third round. Hantuchová reached her second semifinal of the year at the Birmingham Classic in June. She beat Nathalie Dechy, Eleni Daniilidou, Nicole Pratt, and Virginie Razzano, before falling to Miriam Oremans in the semifinals. At the Eastbourne International a week later, Hantuchová entered the doubles with the previous year's champion Ai Sugiyama. They reached the semifinals, where they lost to second seeds Cara Black and Elena Likhovtseva. At Wimbledon the week after, she beat Oremans in a rematch in the first round and lost to Venus Williams in the second round. She also entered the doubles, losing in the third round with Karina Habšudová; and the mixed doubles with Leoš Friedl. Unseeded, they beat Devin Bowen and María José Martínez Sánchez in the first round, first seeds Rennae Stubbs and Todd Woodbridge in the second round, thirteenth seeds Jiří Novák and Miriam Oremans in the third round, fifteenth seeds Donald Johnson and Karina Habšudová in the quarterfinal and Kimberly Po and David Rikl in the semifinal. In the final, they faced Mike Bryan and Liezel Huber, winning in three sets. It was then-18-year-old Hantuchová's first ever Grand Slam final appearance and victory. In July, Hantuchová was knocked out in the first round of the Austrian Open by Maja Palaveršić and played in the PreCon Open in Basel, losing to Marie-Gaianeh Mikaelian in the quarterfinal. She also took part in the doubles, partnering with Magüi Serna and reaching