while the etiology of the condition continues to be debated, various manmade poisons have been suggested as possible causes Yuri Shchekochikhin (d. 2003), Russian investigative journalist; died presumably from poisoning by radioactive thallium Yasser Arafat (d. 2004); reputedly died from liver cirrhosis, which may be a consequence of chronic alcohol use or poisoning. Some Arafat supporters feel it is unlikely that Arafat habitually used alcohol (forbidden by Islam), and so suspect poisoning. However, it is also important to note that cirrhosis is not necessarily caused by alcohol use, or indeed any poison at all. Ardeshir Hosseinpour (d. 2007), Iranian nuclear scientist; possibly assassinated by Mossad with "radioactive poisoning" or "gas poisoning" Poisoners Locusta, professional poisoner hired by Roman emperor Nero and his mother Agrippina the Younger for several murders Lucrezia Borgia (d. 1519), alleged by rivals of the Borgia family to be a poisoner, using a hollow ring to poison drinks with white arsenic Edward Squire (d. 1598), English scrivener and sailor executed for conspiring to poison Queen Elizabeth I and Robert Devereux, 2nd Earl of Essex George Chapman, hanged after murdering three common-law wives Mary Ann Cotton, 19th-century woman who poisoned family members for financial gain Maria Swanenburg, Dutch serial killer who murdered at least 27 and was suspected of killing more than 90 people Thomas Neill Cream (d. 1892), British serial killer Vera Renczi, Romanian serial killer who used arsenic to kill two husbands, a son, and 32 suitors Nannie Doss, black widow Anna Marie Hahn (d. 1938), American serial killer Dr. John Bodkin Adams, British doctor acquitted in 1957 but suspected of killing 163 patients via morphia and barbiturates. Anjette Lyles, American restauranteur responsible for the poisoning deaths of four relatives between 1952–1958 in Macon, Georgia, apprehended on May 6, 1958 and sentenced to death yet later was involuntary commitmented due her to diagnosis of paranoid schizophrenic, died aged 52 on December 4, 1977 at the Central State Hospital, Milledgeville in Georgia. Genene Jones, homicidal nurse Grigory Mairanovsky, received Soviet PhD degree for testing poisons on political prisoners Stella Nickell, used cyanide-laced Excedrin to kill her husband and another woman in suburban Seattle in 1986 Charles Sobhraj, serial killer who preyed on Western tourists throughout Southeast Asia during the 1970s Jim Jones, cult leader responsible for the mass murder–suicide of 918 of his followers in 1978, using cyanide-laced Flavor-Aid at Jonestown, Guyana Michael Swango, American physician and