The bond-dissociation energy (BDE, D0, or DH°) is one measure of the strength of a chemical bond . It can be defined as the standard enthalpy change when is cleaved by homolysis to give fragments A and B, which are usually radical species. The enthalpy change is temperature-dependent, and the bond-dissociation energy is often defined to be the enthalpy change of the homolysis at 0 K (absolute zero), although the enthalpy change at 298 K (standard conditions) is also a frequently encountered parameter. As a typical example, the bond-dissociation energy for one of the C−H bonds in ethane () is defined as the standard enthalpy change of the process , DH°298() = ΔH° = 101.1(4) kcal/mol = 423.0 ± 1.7 kJ/mol = 4.40(2) eV (per bond). To convert a molar BDE to the energy needed to dissociate the bond per molecule, the conversion factor 23.060 kcal/mol (96.485 kJ/mol) for each eV can be used. A variety of experimental techniques, including spectrometric determination of energy levels, generation of radicals by pyrolysis or photolysis, measurements of chemical kinetics and equilibrium, and various calorimetric and electrochemical methods have been used to measure bond dissociation energy values. Nevertheless, bond dissociation energy measurements are challenging and are subject to considerable error. The majority of currently known values are accurate to within ±1 or 2 kcal/mol (4–10 kJ/mol). Moreover, values measured in the past, especially before the 1970s, can be especially unreliable and have been subject to revisions on the order of 10 kcal/mol (e.g., benzene C–H bonds, from 103 kcal/mol in 1965 to the modern accepted value of 112.9(5) kcal/mol). Even in modern times (between 1990 and 2004), the O−H bond of phenol has been reported to be anywhere from 85.8 to 91.0 kcal/mol. On the other hand, the bond dissociation energy of H2 at 298 K has been measured to high precision and accuracy: DH°298(H−H) = 104.1539(1) kcal/mol or 435.780 kJ/mol. Definitions and related parameters The term bond-dissociation energy is similar to the related notion of bond-dissociation enthalpy (or bond enthalpy), which is sometimes used interchangeably. However, some authors make the distinction that the bond-dissociation energy (D0) refers to the enthalpy change at 0 K, while the term bond-dissociation enthalpy is used for the enthalpy change at 298 K (unambiguously denoted DH°298). The former parameter tends to be favored in theoretical and computational work, while the latter is more convenient for thermochemical studies. For