the utmost humiliation and had materially diminished their numbers. In southern Italy there were almost none left; in each of the important communities of Rome, Venice, and Mantua there were about 2,000 Jews; while in all Lombardy there were hardly 1,000. Gregory XIII was not less fanatical than his predecessors; he noticed that, despite papal prohibition, Christians employed Jewish physicians; he therefore strictly prohibited the Jews from attending Christian patients, and threatened with the most severe punishment alike Christians who should have recourse to Hebrew practitioners, and Jewish physicians who should respond to the calls of Christians. Furthermore, the slightest assistance given to the Maranos of Portugal and Spain, in violation of the canonical laws, was sufficient to deliver the guilty one into the power of the Inquisition, which did not hesitate to condemn the accused to death. Gregory also induced the Inquisition to consign to the flames a large number of copies of the Talmud and of other Hebrew books. Special sermons, designed to convert the Jews, were instituted; and at these at least one-third of the Jewish community, men, women, and youths above the age of twelve, was forced to be present. The sermons were usually delivered by baptized Jews who had become friars or priests; and not infrequently the Jews, without any chance of protest, were forced to listen to such sermons in their own synagogues. These cruelties forced many Jews to leave Rome, and thus their number was still further diminished. Varied fortunes Under the following pope, Sixtus V (1585–1590), the condition of the Jews was somewhat improved. He repealed many of the regulations established by his predecessors, permitted Jews to reside in all parts of his realm, and gave Jewish physicians freedom to practice their profession. David de Pomis, an eminent physician, profited by this privilege and published a work in Latin, entitled De Medico Hebraeo, dedicated to Duke Francis of Urbino, in which he proved to the Jews their obligation to consider the Christians as brothers, to assist them, and to attend them. The Jews of Mantua, Milan, and Ferrara, taking advantage of the favorable disposition of the pope, sent to him an ambassador, Bezaleel Massarano, with a present of 2,000 scudi, to obtain from him permission to reprint the Talmud and other Jewish books, promising at the same time to expurgate all passages considered offensive to Christianity. Their demand was granted, partly through