Delta Air Lines is a major United States airline based in Atlanta, Georgia. As of December 31, 2021, Delta mainline aircraft fly to 242 destinations serving 52 countries across six continents. The airline has nine domestic hubs. Destinations Delta Air Lines has flown to the cities below; the table does not show cities that have only seen Delta Connection flights. See also List of Delta Connection destinations References Lists of airline destinations Destinations SkyTeam destinations