Instead of the active ingredient orlistat, the counterfeit drugs contain sibutramine, and at concentrations at least twice the amount recommended for weight loss. In March 2010 Health Canada advised the public that illegal "Herbal Diet Natural" had been found on the market, containing sibutramine, which is a prescription drug in Canada, without listing sibutramine as an ingredient. In October 2010 FDA notified consumers that "Slimming Beauty Bitter Orange Slimming Capsules contain the active pharmaceutical ingredient sibutramine, a prescription-only drug which is a stimulant. Sibutramine is not listed on the product label." In October 2010 the MHRA in the UK issued a warning regarding "Payouji tea" and "Pai You Guo Slim Capsules" which were found to contain undeclared quantities of sibutramine. On December 30, 2010 the FDA released a warning regarding "Fruta Planta" dietary products, which were found to contain undeclared amounts of sibutramine. The recall stated that "there is NO SAFE formula on the US market and that all versions of Fruta Planta contain sibutramine. All versions of the formula are UNSAFE and should not be purchased from any source." In 2011, some illegal weight loss products imported into Ireland have been found to contain sibutramine. In 2012, similar concerns were raised in Australia, where illegal imported supplements have been found to contain sibutramine, resulting in public alerts from Australia's Therapeutic Goods Administration. In October 2011, the FDA warned that 20 brands of dietary supplements were tainted with sibutramine. In a 2018 study the FDA found synthetic additives including sibutramine in over 700 diet supplements marketed as "natural", "traditional" or "herbal remedies". References External links Abbott Press Release on Meridia Withdrawal Sibutramine drug information from Merck Manual. Includes dosage information and a comprehensive list of international brand names U.S. Food and Drug Administration (FDA) product safety website Anorectics Chlorobenzenes Cyclobutanes Dimethylamino compounds AbbVie brands Phenethylamines Prodrugs Serotonin–norepinephrine–dopamine reuptake inhibitors Stimulants Substituted amphetamines Withdrawn drugs World Anti-Doping Agency prohibited substances