of the visual areas in the extrastriate visual cortex. In macaques, it is located anterior to V2 and posterior to posterior inferotemporal area (PIT). It comprises at least four regions (left and right V4d, left and right V4v), and some groups report that it contains rostral and caudal subdivisions as well. It is unknown whether the human V4 is as expansive as that of the macaque homologue which is a subject of debate. V4 is the third cortical area in the ventral stream, receiving strong feedforward input from V2 and sending strong connections to the PIT. It also receives direct input from V1, especially for central space. In addition, it has weaker connections to V5 and dorsal prelunate gyrus (DP). V4 is the first area in the ventral stream to show strong attentional modulation. Most studies indicate that selective attention can change firing rates in V4 by about 20%. A seminal paper by Moran and Desimone characterizing these effects was the first paper to find attention effects anywhere in the visual cortex. Like V2, V4 is tuned for orientation, spatial frequency, and color. Unlike V2, V4 is tuned for object features of intermediate complexity, like simple geometric shapes, although no one has developed a full parametric description of the tuning space for V4. Visual area V4 is not tuned for complex objects such as faces, as areas in the inferotemporal cortex are. The firing properties of V4 were first described by Semir Zeki in the late 1970s, who also named the area. Before that, V4 was known by its anatomical description, the prelunate gyrus. Originally, Zeki argued that the purpose of V4 was to process color information. Work in the early 1980s proved that V4 was as directly involved in form recognition as earlier cortical areas. This research supported the two-streams hypothesis, first presented by Ungerleider and Mishkin in 1982. Recent work has shown that V4 exhibits long-term plasticity, encodes stimulus salience, is gated by signals coming from the frontal eye fields, and shows changes in the spatial profile of its receptive fields with attention. Middle temporal visual area (V5) The middle temporal visual area (MT or V5) is a region of extrastriate visual cortex. In several species of both New World monkeys and Old World monkeys the MT area contains a high concentration of direction-selective neurons. The MT in primates is thought to play a major role in the