of alcoholic drinks carry legal penalties. Iran had previously had a thriving wine industry that disappeared after the Islamic Revolution in 1979. In Greater Persia, mey (Persian wine) was a central theme of poetry for more than a thousand years, long before the advent of Islam. Some Alevi sects – one of the two main branches of Islam in Turkey (the other being Sunni Islam) – use wine in their religious services. Certain exceptions to the ban on alcohol apply. Alcohol derived from a source other than the grape (or its byproducts) and the date is allowed in "very small quantities" (loosely defined as a quantity that does not cause intoxication) under the Sunni Hanafi madhab, for specific purposes (such as medicines), where the goal is not intoxication. However, modern Hanafi scholars regard alcohol consumption as totally forbidden. Health effects Short-term Wine contains ethyl alcohol, the chemical in beer and distilled spirits. The effects of wine depend on the amount consumed, the span of time over which consumption occurs, and the amount of alcohol in the wine, among other factors. Drinking enough to reach a blood alcohol concentration (BAC) of 0.03%-0.12% may cause an overall improvement in mood, increase self-confidence and sociability, decrease anxiety, flushing of the face, and impair judgment and fine motor coordination. A BAC of 0.09% to 0.25% causes lethargy, sedation, balance problems and blurred vision. A BAC from 0.18% to 0.30% causes profound confusion, impaired speech (e.g. slurred speech), staggering, dizziness and vomiting. A BAC from 0.25% to 0.40% causes stupor, unconsciousness, anterograde amnesia, vomiting, and death may occur due to respiratory depression and inhalation of vomit during unconsciousness. A BAC from 0.35% to 0.80% causes coma, life-threatening respiratory depression and possibly fatal alcohol poisoning. The operation of vehicles or machinery while drunk can increase the risk of accident, and many countries have laws against drinking and driving. The social context and quality of wine can affect the mood and emotions. Long-term The main active ingredient of wine is ethanol. A 2016 systematic review and meta-analysis found that moderate ethanol consumption brought no mortality benefit compared with lifetime abstention from ethanol consumption. A systematic analysis of data from the Global Burden of Disease study found that consumption of ethanol increases the risk of cancer and increases the risk of all-cause mortality, and that the most healthful dose of ethanol is zero consumption. Some studies have concluded