Francisco Bay area during this period. Herbert Boyer, a Professor of UCSF’s biochemistry and biophysics department co-founded Genentech, the first therapeutic biotech firm, and UCSF scientists were also involved in the formation of most other major biotech firms in the San Francisco region that date back to the late 1970s and early 1980s. Furthermore, a 2006 analysis of the roots of the ten largest biotech firms measured in terms of their market capitalization in the San Francisco region highlighted the central position of UCSF continued to play within the region’s industry: six biotech firms out of the top ten were either directly or indirectly linked to UCSF—a direct link meaning that the firm was founded by a UCSF scientist, an indirect link meaning that the firm was spun-off from a firm founded by a UCSF scientist. On the clinical side, great advances in patient care, diagnostics, and treatments advanced UCSF's reputation in the health field. 1975 also saw the opening of the UCSF Center in Fresno. Julius R. Krevans, the fifth Chancellor from 1982 to 1993, was a strong advocate of biomedical research and public policy in the health sciences. During his tenure, UCSF rose to become one of the leading recipients of NIH funding. This led to the need for new space, and additions included the Marilyn Reed Lucia Child Care Center in 1978, the Dental Clinics Building (1980), the new Joseph M. Long Hospital in 1983 (which was integrated with the existing Moffitt Hospital), the Beckman Vision Center and the Koret Vision Research Laboratory (1988), and the Kalmanovitz Library (1990). Due to the space constraints of the Parnassus Heights campus, UCSF started looking into expanding into other areas of the city. The university opened UCSF Laurel Heights in 1985 in the Laurel Heights neighborhood. Initially intended for pharmacy school laboratory research and instruction, neighborhood concerns pushed the university to instead employ the building for academic desktop research, social and behavioral science departments, and administrative offices. On the western side of the city, the university acquired Mount Zion Hospital in 1990, which became the second major clinical site and since 1999 has hosted the first comprehensive cancer center in Northern California. Under the chancellorship of Joseph B. Martin, UCSF attempted a short-lived merger of its health system with Stanford Health and laid the groundwork for the expansion into Mission Bay. 21st century A pivotal moment in UCSF history was