The history of Italy from 1559 to 1814 was characterized by the domination of foreign nations over Italy, and corresponds to the period that began in 1559 with the end of the Italian Wars and ended in 1814 with the fall of Napoleon. The following period was characterized by political and social unrest which then led to the unification of Italy, which culminated in 1861 with the proclamation of the Kingdom of Italy. The Italian economy declined during the 1600s and 1700s, as the peninsula was excluded from the rising Atlantic slave trade. After 1600 Italy experienced an economic catastrophe. In 1600 Northern and Central Italy comprised one of the most advanced industrial areas of Europe. There was an exceptionally high standard of living. By 1870 Italy was an economically backward and depressed area; its industrial structure had almost collapsed, its population was too high for its resources, its economy had become primarily agricultural. Wars, political fractionalization, limited fiscal capacity and the shift of world trade to north-western Europe and the Americas were key factors. Following the Peace of Cateau Cambrésis (1559), France renounced its claims in the Duchy of Milan and on the Spanish viceroyalties of the Mezzogiorno. Some of the Italian states were under the rule of powerful dynasties: the Medici in Tuscany, the Farnese in Parma, the Este in Modena, and the Savoy in Piedmont. While the southern kingdoms of Naples, Sicily and Sardinia were under the direct rule of the Spanish Empire. Piedmont returned to the Savoy from France due to the role played by the duke Emmanuel Philibert in the battle of St Quentin during the Italian War of 1551–1559. The House of Savoy was "Italianized" at the end of the Italian wars, as Emmanuel Philibert made Turin the capital of the savoyard state and Italian the official language. The House of Medici kept ruling Florence, thanks to an agreement signed between the Pope and Charles V in 1530, and was later recognized as the ruling family of the Grand Duchy of Tuscany by Pope Pius V. The same Pope arranged the Holy League, a coalition of Venice and other maritime states that defeated the invading Ottoman forces at the naval battle of Lepanto (1571). The Papal States launched the Counter-Reformation, which lasted from the Council of Trent (1545–1563) to the Peace of Westphalia in 1648. This period coincides with the European wars of religion