drugs appears to be increased in patients with compromised liver function. Bioavailability is also increased if another drug competing for first pass metabolism enzymes is given concurrently (e.g., propranolol and chlorpromazine). See also ADME, an acronym in pharmacokinetics and pharmacology standing for absorption, distribution, metabolism, and excretion Biopharmaceutics Classification System Drug Enteral administration Partition coefficient References External links National Library of Medicine, Toxicology Tutor II, Influence of Route of Exposure Pharmacokinetics Medicinal chemistry