limits its ability to match or replace other amphetamine-related stimulants. Lastly, the undesirable side effects of propylhexedrine at recreational doses are often notably worse than amphetamine, non-IV methamphetamine, and other commonly abused stimulants, making it sub-optimal for long term recreational use. Effects Propylhexedrine has sympathomimetic, adrenergic, vasoconstrictive and psychostimulant effects when taken in higher-than-recommended doses. Effects include increased sweating, talkativeness, mydriasis, emotional lability, anorexia, tachycardia, palpitations, dry mouth, bruxism, anxiety, euphoria or dysphoria, increased aggressiveness, paranoia, headache, dizziness, psychosis, slurred or impaired speech, rarely convulsions and serious heart problems. Propylhexedrine can also cause swelling, dryness and irritation of mucous membranes. Injection risks While propylhexedrine has a limited number of administration routes, attempts to extract the drug from the nasal inhaler and then inject it have been reported. Recreational use by intravenous injection (IV) is dangerous, and could result in serious bodily harm or death. IV use of propylhexedrine is known to cause mild side-effects such as transient diplopia. More serious and potentially fatal effects such as brainstem dysfunction and death have been recorded in the medical literature. Reports indicate that propylhexedrine is prepared for IV use by placing the freebase in a solution with hydrochloric acid, to form propylhexedrine HCl. The solution is then heated to evaporate the solvent, and the resulting crystals are dissolved in water for injection. See also Levmetamfetamine Phenylpropanolamine Ephedrine & Pseudoephedrine Phenylephrine References Anorectics Cyclohexyl compounds Decongestants Euphoriants Norepinephrine-dopamine releasing agents Stimulants Sympathomimetics TAAR1 agonists Vasoconstrictors VMAT inhibitors