Louis Brian Piccolo (October 31, 1943 – June 16, 1970) was an American professional football player, a halfback for the Chicago Bears of the National Football League (NFL) for four years. He died at age 26 from embryonal cell carcinoma, an aggressive form of germ cell testicular cancer, first diagnosed after it had spread to his chest cavity. Piccolo was the subject of the 1971 TV movie Brian's Song, with a remake TV movie of the same name filmed in 2001. He was portrayed in the original film by James Caan and by Sean Maher in the 2001 remake. Early life Piccolo was born in Pittsfield, Massachusetts, the youngest of three sons of Joseph and Irene Piccolo. The family moved south to Fort Lauderdale, Florida, when Piccolo was three, due to his parents' concerns for his brother Don's health. Piccolo and his brothers were athletes, and he was a star running back on his high school football team although he considered baseball his primary sport. He graduated from the former Central Catholic High School (now St. Thomas Aquinas High School) in Fort Lauderdale in 1961. Piccolo played college football at Wake Forest in Winston-Salem, North Carolina; his only other scholarship offer was from Wichita State. He led the nation in rushing and scoring during his senior season in 1964, and was named the Atlantic Coast Conference (ACC) Player of the Year, yet went unselected in both the AFL and NFL drafts. In the balloting for the Heisman Trophy won by John Huarte of Notre Dame, Piccolo was tenth, just ahead of Joe Namath of Alabama and future teammate Gale Sayers of Kansas. A season earlier in 1963, Darryl Hill of the University of Maryland was the first and only African-American football player in the ACC. According to Lee Corso, a Maryland assistant coach at that time, Wake Forest had "the worst atmosphere" of any campus the Maryland football team visited. Piccolo went over to the Maryland bench, walked Hill over to the area in front of the student section and put his arm around him, silencing the crowd. Following his spectacular senior season, Piccolo married his high school sweetheart, Joy Murrath, on December 26, 1964. They had three daughters: Lori, Traci, and Kristi. NFL career Because he was not selected in the 1965 NFL draft or AFL draft, Piccolo tried out for the Chicago Bears as a free agent. He