colliculus of the mesencephalon to the medial geniculate nucleus. The inferior colliculus receives input from both the ipsilateral and contralateral cochlear nucleus and respectively the corresponding ears. There is some lateralization, the dorsal projections (containing vertical data) only project to the contralateral inferior colliculus. This inferior colliculus contralateral to the ear it is receiving the most information from, then projects to its ipsilateral medial geniculate nucleus. The inferior colliculus also receives descending inputs from the auditory cortex and auditory thalamus (or medial geniculate nucleus). The medial geniculate body (MGB) is the output connection from inferior colliculus and the last subcortical way station. The MGB is composed of ventral, dorsal, and medial divisions, which are relatively similar in humans and other mammals. The ventral division receives auditory signals from the central nucleus of the IC. Function of IC The majority of the ascending fibers from the lateral lemniscus project to IC, which means major ascending auditory pathways converge here. IC appears as an integrative station and switchboard as well. It is involved in the integration and routing of multi-modal sensory perception, mainly the startle response and vestibulo-ocular reflex. It is also responsive to specific amplitude modulation frequencies and this might be responsible for detection of pitch. In addition, spatial localization by binaural hearing is a related function of IC as well. The inferior colliculus has a relatively high metabolism in the brain. The Conrad Simon Memorial Research Initiative measured the blood flow of the IC and put a number at 1.80 cc/g/min in the cat brain. For reference, the runner up in the included measurements was the somatosensory cortex at 1.53. This indicates that the inferior colliculus is metabolically more active than many other parts of the brain. The hippocampus, normally considered to use up a disproportionate amount of energy, was not measured or compared. Skottun et al. measured the interaural time difference sensitivity of single neurons in the inferior colliculus, and used these to predict behavioural performance. The predicted just noticeable difference was comparable to that achieved by humans in behavioral tests. This suggested that by the level of the inferior colliculus, integration of information over multiple neurons is unnecessary (see population code). Axiomatically determined functional models of spectro-temporal receptive fields in inferior colliculus have been determined by Lindeberg and Friberg in terms of derivatives of Gaussian functions over the log-spectral domain and either Gaussian kernels over time in the