Canada's media coverage of serial killer Karla Homolka to the persecution of Jesus Christ, and suggested that DiNovo was unfit to run for parliament. Many argued that Pupatello took DiNovo's words completely out of context, and opposition politicians accused the Liberals of conducting a smear campaign. The effort backfired, and DiNovo was elected by a significant margin. Pupatello has defended her role in the campaign, saying "If I was presented once again with apparently what is factual and has yet to be refuted and that is sermons that were posted on the world wide web ... I would have exactly the same opinion as I do today". Minister of Economic Development and Trade Pupatello was reassigned as Minister of Economic Development and Trade on September 18, 2006, following the resignation of Joe Cordiano. This was generally interpreted as a demotion, although at least one columnist has suggested that holding an economic portfolio could help Pupatello's long-term political ambitions. Pupatello led provincial trade delegations to Alberta in late 2006 and early 2007, promoting Ontario's business sector to the western province's booming economy. She also took part in a trade mission to India and Pakistan in January 2007, and went on a four-day trade mission to Japan in April of the same year. Her department has also set up a growing number of marketing centres around the world. Minister Responsible for Women's Issues In late 2005, Pupatello introduced a program to assist provincial emergency workers in identifying cases of domestic abuse. She has also introduced several initiatives to assist women from low income backgrounds in entering the job market. She introduced "EqualityRules.ca" in November 2006, to encourage equal relationships between young boys and girls. In the same month, she announced $2.1 million for interpreter services for victims of domestic violence. Minister of International Trade and Investment In September 2008, she was appointed the province's Minister of International Trade and Development, which was created with the mandate of attracting new investment in Ontario. Minister of Economic Development and Trade In June 2009, she was appointed the Minister of Economic Development and Trade, a new ministry that combined three previous ministries: Small Business, International Trade and Investment and Economic Development. In June 2011, she announced that she would not seek re-election in the October 2011 general election. 2013 Ontario Liberal leadership bid On 8 November 2012 Pupatello announced that she was leaving her Bay