The Scientific Revolution was a series of events that marked the emergence of modern science during the early modern period, when developments in mathematics, physics, astronomy, biology (including human anatomy) and chemistry transformed the views of society about nature. The Scientific Revolution took place in Europe starting towards the second half of the Renaissance period, with the 1543 Nicolaus Copernicus publication De revolutionibus orbium coelestium (On the Revolutions of the Heavenly Spheres) often cited as its beginning. The era of the Scientific Renaissance focused to some degree on recovering the knowledge of the ancients and is considered to have culminated in the 1687 Isaac Newton publication Principia which formulated the laws of motion and universal gravitation, thereby completing the synthesis of a new cosmology. The subsequent Age of Enlightenment saw the concept of a scientific revolution emerge in the 18th-century work of Jean Sylvain Bailly, who described a two-stage process of sweeping away the old and establishing the new. There continues to be scholarly engagement regarding the boundaries of the Scientific Revolution and its chronology. Introduction Great advances in science have been termed "revolutions" since the 18th century. For example, in 1747, the French mathematician Alexis Clairaut wrote that "Newton was said in his own life to have created a revolution". The word was also used in the preface to Antoine Lavoisier's 1789 work announcing the discovery of oxygen. "Few revolutions in science have immediately excited so much general notice as the introduction of the theory of oxygen ... Lavoisier saw his theory accepted by all the most eminent men of his time, and established over a great part of Europe within a few years from its first promulgation." In the 19th century, William Whewell described the revolution in science itself – the scientific method – that had taken place in the 15th–16th century. "Among the most conspicuous of the revolutions which opinions on this subject have undergone, is the transition from an implicit trust in the internal powers of man's mind to a professed dependence upon external observation; and from an unbounded reverence for the wisdom of the past, to a fervid expectation of change and improvement." This gave rise to the common view of the Scientific Revolution today: The Scientific Revolution is traditionally assumed to start with the Copernican Revolution (initiated in 1543) and to be complete in the "grand synthesis" of Isaac Newton's 1687 Principia. Much of