Descartes envisioned a new kind of medicine that could grant both physical immortality and stronger minds. In his first edition of Political Justice (1793), William Godwin included arguments favoring the possibility of "earthly immortality" (what would now be called physical immortality). Godwin explored the themes of life extension and immortality in his gothic novel St. Leon, which became popular (and notorious) at the time of its publication in 1799, but is now mostly forgotten. St. Leon may have provided inspiration for his daughter Mary Shelley's novel Frankenstein. There is debate about whether the philosophy of Friedrich Nietzsche can be considered an influence on transhumanism, despite its exaltation of the "Übermensch" (overman or superman), due to its emphasis on self-actualization rather than technological transformation. The transhumanist philosophies of Max More and Stefan Lorenz Sorgner have been influenced strongly by Nietzschean thinking. By way of contrast, The Transhumanist Declaration "...advocates the well-being of all sentience (whether in artificial intellects, humans, posthumans, or non-human animals)". The late 19th to early 20th century movement known as Russian cosmism, by Russian philosopher N. F. Fyodorov, is noted for anticipating transhumanist ideas. Early transhumanist thinking Fundamental ideas of transhumanism were first advanced in 1923 by the British geneticist J. B. S. Haldane in his essay Daedalus: Science and the Future, which predicted that great benefits would come from the application of advanced sciences to human biology—and that every such advance would first appear to someone as blasphemy or perversion, "indecent and unnatural". In particular, he was interested in the development of the science of eugenics, ectogenesis (creating and sustaining life in an artificial environment), and the application of genetics to improve human characteristics, such as health and intelligence. His article inspired academic and popular interest. J. D. Bernal, a crystallographer at Cambridge, wrote The World, the Flesh and the Devil in 1929, in which he speculated on the prospects of space colonization and radical changes to human bodies and intelligence through bionic implants and cognitive enhancement. These ideas have been common transhumanist themes ever since. The biologist Julian Huxley is generally regarded as the founder of transhumanism after using the term for the title of an influential 1957 article. The term itself, however, derives from an earlier 1940 paper by the Canadian philosopher W. D. Lighthall. Huxley describes transhumanism in these terms: Huxley's definition differs, albeit not substantially, from the one commonly in use since the