she would reprise her Chloe O'Brian role in the 2014 limited series 24: Live Another Day. Rajskub appeared in Kelsey Grammer's The Sketch Show on Fox Television, The King of Queens as a character named Priscilla, and in numerous films including Mysterious Skin, Legally Blonde 2, Sweet Home Alabama, Dude, Where's My Car?, Man on the Moon, Punch-Drunk Love, The Anniversary Party, Firewall, Little Miss Sunshine, music videos for Beck, Weezer and Sheryl Crow, as well as portraying a blind woman in the film Road Trip. Rajskub was part of a comic duo (with Karen Kilgariff) called Girls Guitar Club. In 2006, she made a cameo appearance in "Partings", the 6th season finale of Gilmore Girls, where she played a trobairitz looking for her big break. (Rajskub had previously appeared on Gilmore Girls as the female lead in A Film by Kirk, a short film made by the character Kirk Gleason.) She has volunteered as an actress with the Young Storytellers Program. She has an educational background as a painter, having attended the San Francisco Art Institute. Rajskub has been nominated twice for a Screen Actors Guild Award; once in 2005, and again in 2007 for Outstanding Performance by an Ensemble in a Drama Series. She guest-starred on Flight of the Conchords episode "Prime Minister" as Karen, an Art Garfunkel fanatic. She guest-starred as "Gail the Snail" in an episode of It's Always Sunny in Philadelphia titled "The Gang Gives Frank an Intervention", and reprised the role in the ninth-season finale, "The Gang Squashes Their Beefs," and season thirteen's "The Gang Beats Boggs: Ladies Reboot." In 2009, she also appeared in the film Julie & Julia as Sarah, one of Julie Powell's close friends. In 2010, Rajskub performed stand-up on John Oliver's New York Stand Up Show. In June 2010, she appeared in the "Lovesick" episode during the second season of the USA series Royal Pains. From July through October 2010, she performed in her solo show, Mary Lynn Spreads Her Legs, at the Steve Allen Theater in Los Angeles. Reviewer F. Kathleen Foley of the Los Angeles Times wrote "that cheerfully vulgar title sums up the overall tone, which is often breezily obscene". The show, written by Rajskub with help from director/developer Amit Itelman, was inspired by Rajskub's experiences with pregnancy, childbirth, and early motherhood. In January 2011, Rajskub guest-starred in the episode "Our Children, Ourselves" on the second