may be particularly important after the induction of NOS2. Inhibitors Ronopterin (VAS-203), also known as 4-amino-tetrahydrobiopterin (4-ABH4), an analogue of BH4 (a cofactor of NOS), is an NOS inhibitor that is under development as a neuroprotective agent for the treatment of traumatic brain injury. Other NOS inhibitors that have been or are being researched for possible clinical use include cindunistat, A-84643, ONO-1714, L-NOARG, NCX-456, VAS-2381, GW-273629, NXN-462, CKD-712, KD-7040, and guanidinoethyldisulfide, among others. See also Biological functions of nitric oxide Nitric-oxide synthase (NAD(P)H-dependent) Nitric oxide synthase 2 (inducible) References External links The Nobel Prize in Physiology or Medicine 1998 University of Edinburgh, School of Chemistry - NO Synthase Nitric Oxide Synthase in Proteopedia EC 1.14.13 Heme-thiolate proteins