Blood Canticle is a 2003 horror novel by American writer Anne Rice, the tenth book in her The Vampire Chronicles series. The novel includes some characters who cross over from Rice's Lives of the Mayfair Witches trilogy (1990–1994), concluding the unified story begun in Merrick (2000) and continued in Blackwood Farm (2002). Blood Canticle was originally intended to conclude the saga of Rice's famed vampire Lestat de Lioncourt, but in March 2014 she announced a sequel titled Prince Lestat. Plot summary Narrated by the vampire Lestat de Lioncourt, Blood Canticle finds young Mayfair witch and heiress Mona slowly dying, afflicted with a mysterious disease brought on by the birth of her daughter Morrigan. Over time, Mona and her guardian, Rowan Mayfair, reveal more and more about the powerful genetic plague that has haunted the Mayfairs for generations: their connection to the Taltos, an advanced species of human to which both women have given birth. Mona and the young vampire Tarquin "Quinn" Blackwood are in love. Lestat turns a dying Mona into a vampire so that the lovers can be together forever. While trying to prevent Mona's family from discovering her transformation, Lestat falls in love with the married Rowan, and she secretly pines for him as well. As Mona adjusts to her new power, Lestat enlists the ancient vampire Maharet to help find Mona's Taltos child. Lestat, Quinn and Mona arrive at the remote island colony of the Taltos, but instead of finding a secluded utopia, they discover that years of criminal intrigue and civil war have taken their toll. The remaining Taltos join the Mayfair clan at the Mayfair Medical Center where they intend to safely learn and grow as a family. Mona and Quinn are instructed in the proper ways of vampirism by Maharet and her twin Mekare. Rowan seeks out Lestat, half in love with him but torn by her love for her husband Michael. Exhausted by her life, she requests that he make her a vampire. Lestat declines, pained though he is, because she is a guiding force for the Mayfair family and he cannot take her away from it. Crossovers Some characters from Rice's Lives of the Mayfair Witches trilogy (1990–1994) appear in Merrick (2000), and later Blackwood Farm (2002) and Blood Canticle. Audiobooks In 2003, Penguin Random House Audio released an abridged audiobook adaptation of Blood Canticle, narrated by Stephen Spinella, as well as