effective in many ways, its high opiate content also made it very addictive, and deaths from overdoses, either accidental or deliberate, became a frequent occurrence. A common feature of the coroner's report in such cases would be the description of the deceased's body being found in a flat or bedsit littered with empty Chlorodyne bottles. Over the decades of the twentieth century, the cannabis was removed from the formulation, and the amount of opiates in the medicine were progressively reduced. The name of Collis Browne lives on in Britain in a mixture sold under the trade name "J Collis Browne's Mixture" for the relief of coughs and diarrhea. This modern formulation contains morphine and peppermint oil. The active ingredients per 5ml are: morphine hydrochloride equivalent to 1.0mg anhydrous morphine, peppermint oil 1.5 microlitres. The other ingredients are: ethanol (alcohol), benzoic acid (E210), capsicum tincture, caramel (E150), menthol, citric acid (E330), hypromellose, sorbitol solution (E420), treacle (containing sucrose and fructose), purified water. References Analgesics Patent medicines