Tylosis may refer to: In medicine Diffuse nonepidermolytic palmoplantar keratoderma, a skin condition of the palms and soles Howel–Evans syndrome, a skin condition of the palms and soles that is also associated with esophageal cancer Other uses Tylosis (botany), a process in tree decay Tylosis (beetle), a genus of longhorn beetle Palmoplantar keratodermas