Eichinger, head of Constantin Film, was enthusiastic, so Anderson developed it into the script for Resident Evil. In late 2000, Anderson was announced as director and writer, and Resident Evil re-entered pre-production stages. Anderson stated the film would not include any tie-ins with the video game series as "under-performing movie tie-ins are too common and Resident Evil, of all games, deserved a good celluloid representation". Casting In early 2001, Michelle Rodriguez, James Purefoy and Milla Jovovich were the first of the cast to be signed on the project. David Boreanaz was intended to portray the male cop lead of Matt Addison; however, he turned down the role to continue work on the WB series Angel. Boreanaz suggested that he was in negotiations to have a smaller role in the film, claiming "Resident Evil is still there, a possibility, So, yeah, I'll see what happens", but he later declined the role. The role of Matt Addison then went to Eric Mabius who was cast in March 2001, along with Heike Makatsch, who was cast as Matt Addison's sister Lisa Addison, an employee working for Umbrella's Hive facility. Filming and story development In early March 2001, half of the film was to be shot in Adlershof Studios in Berlin and its surroundings. Principal photography began on March 5, 2001 at numerous locations including the then unfinished station U-Bahnhof Bundestag of the Berlin U-Bahn, Landsberger Allee, Kaserne Krampnitz and the Schloss Lindstedt. The film was originally subtitled as Resident Evil: Ground Zero when the movie was considered a prequel to the games, but the subtitle was removed due to 9-11. The film's synopsis as of March 16, 2001 revealed that Jovovich's Alice and Rodriguez's Rain were the leaders of a commando team sent in to prevent a viral outbreak from spreading to the rest of the world. The character of the Red Queen was added into the film's story as an homage to Lewis Carroll's Alice in Wonderland. During production, professional dancers were hired to star as zombies as they had better control of their body movements. While computer effects were used on some zombies, much of the undead appearances were accomplished through make-up while their movements were a more laissez-faire approach, as Anderson told the actors to move however they thought a zombie would, given their conditions. Whilst filming, there was a shortage of manpower where the available dancers were not enough