series progresses, Conan befriends biochemist Shiho Miyano, a former member of the Black Organization and inventor of the APTX-4869 drug. She and her sister had grown up within the organization, as their scientist parents had been members too, before their deaths. After her sister was killed by Gin, she took the poison to commit suicide. However, like Shinichi, her age regressed and she shrank back to a small child's size. She then escapes and adopts the pseudonym Ai Haibara (Anita Hailey). Dr. Agasa ends up taking her in, and she vows to help Conan take down the Black Organization. She later invents a prototype antidote to the APTX-4869 allowing Conan to temporarily become Shinichi again, which Conan uses on occasion to fool Ran when she suspects his true identity. During the events of Holmes' Revelation, Shinichi, while in his original form, confesses his feelings to Ran in London. In The Scarlet School Trip, Ran returns those feelings by giving Shinichi a kiss on the cheek. Conan's investigation of the Black Organization leads him to discover the American FBI's existence in Japan, as they are also investigating the syndicate. The head of the syndicate, often referred to as 'that person' and 'boss' by syndicate members, who is at least one-hundred and thirty, is Renya Karasuma. However, the FBI and Conan are currently unaware of this. His collaboration with FBI agents Jodie Starling and Shuichi Akai allows them to capture organization member Kir. They discover she is really an undercover CIA agent and return her to the organization to continue to spy from within. In other media Shinichi Kudo has appeared in all of the feature films of the series, both the original video animation series (Shōnen Sunday Original animations and the Magic Files), the two-hour cross-over television special Lupin the 3rd vs Detective Conan, and is the protagonist in all Case Closed-related video games. He is the protagonist in the novels of the series. In the 2006–2007 live-action series, he is portrayed by Shun Oguri as a teenager and Nao Fujisaki in child form. In the 2011 live-action movie and TV drama series, Junpei Mizobata portrays the teenage Shinichi. In 2006, the Japanese government used Conan in campaigns to help promote crime awareness among children. Targeting the same audience, Japan's Ministry of Foreign Affairs used Conan and his friends in two pamphlets: one to promote the ministry's mission, the other to