of Lancet Medical Journal on March 8, 2005, detailed information about a new stem cell line that was derived from human embryos under completely cell- and serum-free conditions. After more than 6 months of undifferentiated proliferation, these cells demonstrated the potential to form derivatives of all three embryonic germ layers both in vitro and in teratomas. These properties were also successfully maintained (for more than 30 passages) with the established stem cell lines. Muse cells Muse cells (Multi-lineage differentiating stress enduring cell) are non-cancerous pluripotent stem cell found in adults. They were discovered in 2010 by Mari Dezawa and her research group. Muse cells reside in the connective tissue of nearly every organ including the umbilical cord, bone marrow and peripheral blood. They are collectable from commercially obtainable mesenchymal cells such as human fibroblasts, bone marrow-mesenchymal stem cells and adipose-derived stem cells. Muse cells are able to generate cells representative of all three germ layers from a single cell both spontaneously and under cytokine induction. Expression of pluripotency genes and triploblastic differentiation are self-renewable over generations. Muse cells do not undergo teratoma formation when transplanted into a host environment in vivo, eradicating the risk of tumorigenesis through unbridled cell proliferation. See also Embryoid body Embryonic Stem Cell Research Oversight Committees Fetal tissue implant Induced stem cells KOSR (KnockOut Serum Replacement) Stem cell controversy References External links Understanding Stem Cells: A View of the Science and Issues from the National Academies National Institutes of Health University of Oxford practical workshop on pluripotent stem cell technology Fact sheet on embryonic stem cells Fact sheet on ethical issues in embryonic stem cell research Information & Alternatives to Embryonic Stem Cell Research A blog focusing specifically on ES cells and iPS cells including research, biotech, and patient-oriented issues Stem cells Biotechnology Embryology 1981 in biotechnology Sociobiology