species of poison dart frogs are Neotropical in origin. Wild-caught specimens can maintain toxicity for some time (this can be obtained through a form of bioaccumulation), so appropriate care should be taken when handling them. While scientific study on the lifespan of poison dart frogs is scant, retagging frequencies indicate it can range from one to three years in the wild. However, these frogs typically live for much longer than that in captivity, having been reported to live as long as 25 years. These claims also seem to be questionable, since many of the larger species take a year or more to mature, and Phyllobates species can take more than two years. In captivity, most species thrive where the humidity is kept constant at 80 to 100% and where the temperature is around to during the day and no lower than to at night. Some species tolerate lower temperatures better than others. Conservation status Many species of poison dart frogs have recently experienced habitat loss, chytrid diseases, and collection for the pet trade. Some are listed as threatened or endangered as a result. Zoos have tried to counteract this disease by treating captive frogs with an antifungal agent that is used to cure athlete's foot in humans. Behavior as tadpoles The poison dart frog is known for its aggressive and predatory behavior. As tadpoles, the individuals of the genus Dendrobates are said to exhibit some unique cannibalistic tendencies, along with many other forms of predatory behavior. Dendrobates tadpoles that either consumed three or more conspecific tadpoles and/or relatively large larvae of a specific species of mosquito by the name of Trichoprosopon digitatum common in their environment led them to having a much higher growth rate and typically lived much longer lives. Reasons for this behavior could be that predation and aggression was selected for and favored for a few reasons. One reason is to eliminate predators, and the second reason is that it serves as a source of food in habitats that were low in resources. This predation could have evolved over time and led to cannibalism as another form of predatory behavior that had benefitted individuals survival fitness. However one observation has been noted in the general characteristic of Dendrobates tadpoles including D. arboreus, D. granuliferus, D. lehmanni, D. occultator, D. pumilio, D. speciosus, and many other Dendrobates species is that they have reduced mouth parts as young tadpoles