in patients with left main coronary involvement. However, human clinical trials have been slow to provide clinical & medical evidence, partly because the asymptomatic nature of atheromata make them especially difficult to study. Promising results are found using carotid intima-media thickness scanning (CIMT can be measured by B-mode ultrasonography), B-vitamins that reduce a protein corrosive, homocysteine and that reduce neck carotid artery plaque volume and thickness, and stroke, even in late-stage disease. Additionally, understanding what drives atheroma development is complex with multiple factors involved, only some of which, such as lipoproteins, more importantly lipoprotein subclass analysis, blood sugar levels and hypertension are best known and researched. More recently, some of the complex immune system patterns that promote, or inhibit, the inherent inflammatory macrophage triggering processes involved in atheroma progression are slowly being better elucidated in animal models of atherosclerosis. See also Angiogram ApoA-1 Milano Atherosclerosis Atherothrombosis Coronary circulation Coronary catheterization EBT Hemorheologic-Hemodynamic Theory of Atherosclerosis Lipoprotein LDL, HDL, IDL and VLDL References Further reading External links Vascular diseases Diseases of arteries, arterioles and capillaries fr:Athérome