HPC may refer to: Computing High-performance computing HPC Challenge Benchmark Hasty Pudding cipher, in cryptography Science and medicine Health Professions Council, a UK regulator, later Health and Care Professions Council Hemangiopericytoma, a type of soft tissue sarcoma Hilbert system, also referred to as Hilbert Propositional Calculus History of presenting complaint, in a medical history in UK Hot potassium carbonate, a method for carbon dioxide removal in gas streams Hydroxypropyl cellulose, a derivative of cellulose Heterotrophic Plate Count a procedure for estimating the number of live, culturable heterotrophic bacteria in water Other uses Hinkley Point C nuclear power station, under construction in England Hmar People's Convention, a political party in India Ho-Ping Power Company, an independent power producer in Taiwan Hydraulic Press Channel, a YouTube channel Hydrometeorological Prediction Center, former name of the US Weather Prediction Center Croatian Orthodox Church () Hi-Point Carbine, a pistol-caliber rifle manufactured by Hi-Point Firearms See also Windows HPC Server 2008, an operating system for high-performance computing by Microsoft