any U.S. nuclear test, 15 Mt, though again, a substantial fraction came from fission. In the Teller–Ulam design, the fission and fusion stages were kept physically separate in a reflective cavity. The radiation from the exploding fission primary brought the fuel in the fusion secondary to critical density and pressure, setting off thermonuclear (fusion) chain reactions, which in turn set off a tertiary fissioning of the bomb's U fusion tamper and casing. Consequently, this type of bomb is also known as a "fission-fusion-fission" device. The Soviet researchers, led by Andrei Sakharov, developed and tested their first Teller–Ulam device in 1955. The publication of the Bravo fallout analysis was a militarily sensitive issue, with Joseph Rotblat possibly deducing the staging nature of the Castle Bravo device by studying the ratio and presence of tell-tale isotopes, namely uranium-237, present in the fallout. This information could potentially reveal the means by which megaton-yield nuclear devices achieve their yield. Soviet scientist Andrei Sakharov hit upon what the Soviet Union regarded as "Sakharov's third idea" during the month after the Castle Bravo test, the final piece of the puzzle being the idea that the compression of the secondary can be accomplished by the primary's X-rays before fusion began. The Shrimp device design later evolved into the Mark 21 nuclear bomb, of which 275 units were produced, weighing and measuring long and in diameter. This 18-megaton bomb was produced until July 1956. In 1957, it was converted into the Mark 36 nuclear bomb and entered into production again. Health impacts Following the test, the United States Department of Energy estimated that 253 inhabitants of the Marshall Islands were impacted by the radioactive fallout. This single test exposed the surrounding populations to varying levels of radiation. The fallout levels attributed to the Castle Bravo test are the highest in history. Populations neighboring the test site were exposed to high levels of radiation resulting in mild radiation sickness of many (nausea, vomiting, diarrhea). Several weeks later, many people began suffering from alopecia (hair loss) and skin lesions as well. The exposure to fallout has been linked to increase the likelihood of several types of cancer such as leukemia and thyroid cancer. The relationship between Iodine-131 levels and thyroid cancer is still being researched. There are also correlations between fallout exposure levels and diseases such as thyroid disease like hypothyroidism. Populations of the Marshall Islands that received significant exposure