Galerius defeats Sasanian king Narseh at the Battle of Satala, capturing Ctesiphon and forcing the Peace of Nisibis upon Persia, ending hostilities between the Roman and Sasanian Empires. 311: The emperor Galerius issues the Edict of Serdica, ending the Diocletianic Persecution of Christianity in the Roman Empire. 313: Constantine I defeats the augustus Maxentius at the Battle of the Milvian Bridge and becomes augustus of the West. Constantine and Licinius issued the Edict of Milan. 324: Constantine I and Crispus defeat Licinius and Licinius II at the Battles of Chrysopolis and of the Hellespont. 325: First Council of Nicaea is convened by Constantine I. 330: 11 May dedication of the Column of Constantine at Constantinople marks the inauguration of the new city, New Rome. 363: The pagan emperor Julian attacks the Sasanian Empire in his Persian War and is decisively defeated by Shapur II. Jovian becomes the new emperor and cedes lands in a Perso-Roman Peace Treaty. 376: The Thervingi under Fritigern, fleeing the Hunnic Invasion, are allowed to cross the Danube into Moesia. 378: At the Battle of Adrianople, Eastern Roman Emperor Valens is defeated and killed by Gothic rebels. First Siege of Constantinople by the Goths. 380: Theodosius I, Gratian, and Valentinian II issue the Edict of Thessalonica, establishing Nicene Christianity as the state church of the Roman Empire. 381: First Council of Constantinople is convened by Theodosius in the Church of Hagia Irene. 382: Influenced by Saint Ambrose, Roman Emperor Gratian persecutes paganism, removing the Altar of Victory. 394: At the Battle of the Frigidus, Theodosius I defeats Eugenius, last pagan Roman augustus. 395: The Huns invade Persia. 395: Roman Emperor Theodosius I outlaws all pagan religions in favour of Christianity. 405: The Vulgate Bible is completed, mostly by the theologian Jerome. The Vulgate will be the only Bible widely used in the Latin West until the Reformation. 406: The Crossing of the Rhine by a confederacy of Germanic tribes marks a turning point in the Migration Period. 410: Alaric I sacks Rome for the first time since 390 BC. Council of Seleucia-Ctesiphon convoked by Yazdegerd I, organizing the Church of the East. Final Roman departure from Britain. 413: Theodosian Walls around Constantinople are completed, as the largest system of fortifications in Europe. Constantinople as a result will not be conquered by a siege until 1204. 415: Hypatia of Alexandria, pagan female mathematician is murdered by a