revert to normal. The ACh diffuses across the synaptic cleft and binds to receptors on the post synaptic membrane, causing an influx of sodium (Na+,) resulting in depolarization. If large enough, this depolarization results in an action potential. To prevent constant stimulation once the ACh is released, an enzyme called acetylcholinesterase is present in the endplate membrane close to the receptors on the post synaptic membrane, and quickly hydrolyses ACh. Names Pyridostigmine bromide is available under the trade names Mestinon (Valeant Pharmaceuticals), Regonol and Gravitor (SUN Pharma). References External links Acetylcholinesterase inhibitors Dimethylamino compounds Pyridinium compounds Aromatic carbamates Peripherally selective drugs World Health Organization essential medicines Wikipedia medicine articles ready to translate