Matagalpa () is a department in central Nicaragua. It covers an area of 6,804 km2 and has a population of 600,057 (2021 est). The capital is the city of Matagalpa with a population of about 111,000. Matagalpa is the second largest region of the country in population size, and the fifth in area (after the North Atlantic, the South Atlantic, Jinotega and Río San Juan). Matagalpa is the most diversified region producing coffee, cattle, milk products, vegetables, wood, gold, flowers. Its extensive forests, rivers and geography are suited for ecotourism. Municipalities Ciudad Darío Esquipulas Matagalpa Matiguas Muy Muy Rancho Grande Río Blanco San Dionisio San Isidro San Ramón Sébaco Terrabona Tuma-La Dalia References External links Portal del Norte de Nicaragua Departments of Nicaragua