Whittington Hospital is a district general and teaching hospital of UCL Medical School and Middlesex University School of Health and Social Sciences. Located in Upper Holloway, it is managed by Whittington Health NHS Trust, operating as Whittington Health, an integrated care organisation providing hospital and community health services in the north London boroughs of Islington and Haringey. Its Jenner Building, a former smallpox hospital, is a Grade II listed building. History The first hospital on the site was St Anthony's Chapel and Lazar House, a facility built for lepers in 1473. It closed during the Dissolution of the Monasteries in the mid-16th century. The current hospital has its origins in the Small Pox and Vaccination Hospital, built in 1848. It was designed by the architect Samuel Daukes as one of two isolation hospitals in London (the other was the London Fever Hospital in Liverpool Road) intended to care for smallpox patients during the epidemic at that time. The hospital, instituted in 1746, was removed from the original central London site to make way for the building of King’s Cross station. After smallpox treatment services transferred to Clare Hall Manor at South Mimms in 1896, the hospital was officially re-opened by the Duke and Duchess of York as a workhouse infirmary with the addition of a large adjacent building in 1900. Originally called Highgate Hill Infirmary, in 1914, it became Islington Infirmary and by 1920, five linked blocks had been added to the south of the original building. The hospital was taken over by the London County Council in 1930 and renamed St Mary's Hospital. In 1948, St Mary's Hospital (subsequently known as St Mary's Wing) amalgamated with Highgate Hospital (subsequently known as Highgate Wing) and Archway Hospital (subsequently known as Archway Wing) to form the Whittington Hospital. The three hospitals had been brought together under the control of the Archway Group Hospital Management Committee on the establishment of the National Health Service in 1946. The combined facility was named after Sir Richard Whittington, an English merchant, who had left a large sum to charitable causes supporting people in need. In 1977, a new block containing accident and emergency and outpatient facilities was opened by the North West Metropolitan Regional Hospital Board on the St Mary's Wing site on Highgate Hill. Further expansion took place in 1983, when the City of London Maternity Hospital was closed and amalgamated with the Obstetric