through the American Medical College Application Service (AMCAS). Other routes of entry include the eight-year Program in Liberal Medical Education (PLME) and a small number of linkage programs. The 2016 matriculating class had an average GPA of 3.8 and MCAT score of 514. Students interested in studying at Alpert Medical School may apply through a variety of admissions routes designed to enroll a diverse and highly qualified student body. Approximately 30% of the entering class is composed of students from the 8-year Program in Liberal Medical Education (PLME) and special linkage agreement programs. In 2004, the school began to accept premedical students from other colleges and universities via AMCAS through a standard route of admissions. According to the school's website, for the Fall 2016 entering class, Alpert Medical School received 6,374 secondary applications and interviewed 370 candidates through the AMCAS route." Curriculum A restructuring of the pre-clinical curriculum was implemented in 2006, with the goal of achieving an integrated, contemporary and flexible medical curriculum. Its design was predicated on the vision that tomorrow's physician must be an IT-savvy lifelong learner who is scientifically and clinically enlightened, familiar with alternative and complementary healing traditions, patient and service-centered, and who understands the economic underpinnings of the US health care system. At the heart of the curriculum redesign are the two-year basic science component (Integrated Medical Sciences I-IV), Doctoring (which focuses on clinical skills and professionalism), and the Scholarly Concentrations Program. Integrated Medical Sciences I: IMS-I provides students with foundations of cell biology, cell physiology, biochemistry, nutrition, immunology and genetics, all of which are integrated with gross anatomy and microscopic anatomy. IMS-I also includes general pathology in which students are introduced to concepts underlying the mechanisms of disease. This foundation forms the basis for the subsequent systems-based blocks of IMS II through IV. Brain Sciences, the first module of IMS II, integrates head and neck anatomy with neurobiology, behavior, pathophysiology and neuropharmacology. Microbiology is integrated with infectious diseases and relevant pharmacology and epidemiology. In the final block of IMS-II, Endocrinology, endocrine physiology has been incorporated into the endocrine pathophysiology, pathology and pharmacology content. Integrated Medical Sciences III and IV: Students continue with a systems-based approach in Year II: The course sections are cardiology, nephrology, pulmonology, hematology, gastroenterology, human reproduction, growth, and development, and supporting structures (dermatology, rheumatology, and orthopedics). Doctoring is a required skills-based course for all first- and second-year medical students designed