very vulnerable to the predations of the powerful nation-states, France and Spain, that had forged themselves during the previous century. Alexander VI now followed the general tendency of all the princes of the day to crush the great feudatories and establish a centralized despotism. In this manner, he was able to take advantage of the defeat of the French in order to break the power of the Orsini. From that time on, Alexander was able to build himself an effective power base in the Papal States. Virginio Orsini, who had been captured by the Spanish, died a prisoner at Naples, and the Pope confiscated his property. The rest of the Orsini clan still held out, defeating the papal troops sent against them under Guidobaldo da Montefeltro, Duke of Urbino and Giovanni Borgia, Duke of Gandia, at Soriano (January 1497). Peace was made through Venetian mediation, the Orsini paying 50,000 ducats in exchange for their confiscated lands; the Duke of Urbino, whom they had captured, was left by the pope to pay his own ransom. The Orsini remained very powerful, and Pope Alexander VI could count on none but his 3,000 Spanish troops. His only success had been the capture of Ostia and the submission of the Francophile cardinals Colonna and Savelli. Then occurred a major domestic tragedy for the house of Borgia. On 14 June, his son the Duke of Gandia, who was lately created Duke of Benevento and had a questionable lifestyle, disappeared; the next day, his corpse was found in the Tiber. Alexander, overwhelmed with grief, shut himself up in Castel Sant'Angelo. He declared that henceforth the moral reform of the Church would be the sole object of his life. Every effort was made to discover the assassin. No conclusive explanation was ever reached, and it may be that the crime was simply as a result of one of the Duke's sexual liaisons. Crime There is no evidence that the Borgias resorted to poisoning, judicial murder, or extortion to fund their schemes and the defense of the Papal States. The only contemporary accusations of poisoning were from some of their servants, extracted under torture by Alexander's bitter enemy Della Rovere, who succeeded him as Pope Julius II. Savonarola The debased state of the curia was a major scandal. Opponents, such as the powerful Florentine friar Girolamo Savonarola, launched invectives against papal corruption and appealed for a general council