The Roman Inquisition, formally the Supreme Sacred Congregation of the Roman and Universal Inquisition, was a system of partisan tribunals developed by the Holy See of the Roman Catholic Church, during the second half of the 16th century, responsible for prosecuting individuals accused of a wide array of crimes according to Roman Catholic law and doctrine, relating to catholic religious life or alternative religious or secular beliefs. It was established in 1542 by the leader of the Roman Catholic Church, Pope Paul III. In the period after the Medieval Inquisition, it was one of three different manifestations of the wider Catholic Inquisition along with the Spanish Inquisition and Portuguese Inquisition. Function and functioning Main function of the institution was to maintain and implement papal bulls and other church rulings, in addition to their function of administering legalistic ramifications upon deviants of Catholic orthodoxy within states that cooperated with the pope and ostensibly exhibiting proper procedure to Catholic states in the process of formulating the Counter-Reformation. The papal bull Ad abolendam, by Lucius III, prescribed penalties for heretical clerics and laymen and established a procedure of systematic inquisition by bishops; the third canon of the fourth Lateran Concile (1215) specified procedures against heretics and their accomplices. Clerics were to be degraded from their orders, lay persons were to be branded as infamous and not be admitted to public offices or councils or to run a business, will not have the freedom to make a will nor shall succeed to an inheritance, goods were to be confiscated. A secular leader who "neglects to cleanse his territory of this heretical filth" would be excommunicated and the supreme pontiff could declare his vassals absolved from their fealty to him and make the land available for occupation by Catholics who would possess it unopposed and preserve it in the purity of the faith. The organisational system of the Roman Inquisition did differ essentially from that of the Medieval Inquisition. Typically, the pope appointed one cardinal to preside over meetings of the Congregation. Though often referred to in historical literature as Grand Inquisitors, the role was substantially different from the formally appointed Grand Inquisitor of the Spanish Inquisition. There were usually ten other cardinals who were members of the Congregation, as well as a prelate and two assistants all chosen from the Dominican Order. The Holy Office also had an international group of consultants; experienced scholars