the autumn of 1465, Edward IV granted Warwick 1,000 pounds for the expenses of his younger brother's tutelage. With some interruptions, Richard stayed at Middleham either from late 1461 until early 1465, when he was 12 or from 1465 until his coming of age in 1468, when he turned 16. While at Warwick's estate, it is likely that he met both Francis Lovell, who was his firm supporter later in his life, and Warwick's younger daughter, his future wife Anne Neville. It is possible that even at this early stage Warwick was considering the king's brothers as strategic matches for his daughters, Isabel and Anne: young aristocrats were often sent to be raised in the households of their intended future partners, as had been the case for the young dukes' father, Richard of York. As the relationship between the king and Warwick became strained, Edward IV opposed the match. During Warwick's lifetime, George was the only royal brother to marry one of his daughters, the elder, Isabel, on 12 July 1469, without the king's permission. George joined his father-in-law's revolt against the king, while Richard remained loyal to Edward, even though he was rumoured to have been sleeping with Anne. Richard and Edward were forced to flee to Burgundy in October 1470 after Warwick defected to the side of the former Lancastrian queen Margaret of Anjou. In 1468, Richard's sister Margaret had married Charles the Bold, the Duke of Burgundy, and the brothers could expect a welcome there. Edward was restored to the throne in the spring of 1471, following the battles of Barnet and Tewkesbury, in both of which the 18-year-old Richard played a crucial role. During his adolescence, and due to a cause that is unknown, Richard developed a sideways curvature of the spine (Scoliosis). In 2014, after the discovery of Richard's remains, the osteoarchaeologist Dr. Jo Appleby, of Leicester University's School of Archaeology and Ancient History, imaged the spinal column, and reconstructed a model using 3D printing, and concluded that though the spinal scoliosis looked dramatic, it probably did not cause any major physical deformity that could not be disguised by clothing. Marriage and family relationships Following a decisive Yorkist victory over the Lancastrians at the Battle of Tewkesbury, Richard married Anne Neville on 12 July 1472. Anne had previously been wedded to Edward of Westminster, only son of Henry VI, to seal her father's allegiance to