sopra Minerva in Rome, which was designed by Baccio Bandinelli. Clement's biographer Emmanuel Rodocanachi writes, "in accordance with the custom of those times, people attributed his death to poison"—specifically, poisoning by death cap mushroom., who completely rejects the theory of poison. Clement's symptoms and the length of his illness do not support this hypothesis. Legacy Political legacy Clement VII's papacy is generally regarded as one of history's most tumultuous; opinions of Clement himself are often nuanced. For example, Clement's contemporary Francesco Vettori writes that he "endured a great labor to become, from a great and respected cardinal, a small and little-esteemed pope", but also that "if one considers the lives of previous popes one may truly say that, for more than a hundred years, no better man than Clement VII sat upon the Throne. Nevertheless, it was in his day that the disaster took place while these others, who were filled with all vices, lived and died in felicity—as the world sees it. Neither should we seek to question the Lord, our God, who will punish—or not punish–in what manner and in what time it pleases him.’" The disasters of Clement's pontificate—the Sack of Rome and the English Reformation—are regarded as turning points in the histories of Catholicism, Europe, and the Renaissance. Modern historian Kenneth Gouwens writes, "Clement's failures must be viewed above all in the context of major changes in the dynamics of European politics. As warfare on the Italian peninsula intensified in the mid-1520s, the imperative of autonomy [for the Catholic Church and Italy] required enormous financial outlays to field standing armies. Political survival perforce eclipsed ecclesiastical reform as a short-term goal, and the costs of war necessitated the curtailment of expenditure on culture. Clement pursued policies consistent with those of his illustrious predecessors Julius II and Leo X; but in the 1520s, those policies could but fail.... Reform of the Church, to which his successors would turn, required resources and concerted secular support that the second Medici pope was unable to muster." Regarding Clement's struggle to liberate Italy and the Catholic Church from foreign domination, historian Fred Dotolo writes that "one might see in his papacy a vigorous defense of papal rights against the growth of monarchial power, a diplomatic and even pastoral struggle to retain the ancient division within Christendom of the priestly and kingly offices. Should the new monarchs of the early modern period reduce