and low, depending on their molecular weight. Low phthalates such as DEHP and DBP have increased health risks and are generally being phased out. High-molecular-weight phthalates such as DINP, DIDP are generally considered safer While di-2-ethylhexylphthalate (DEHP) has been medically approved for many years for use in medical devices, it was permanently banned for use in children's products in the US in 2008 by US Congress; the PVC-DEHP combination had proved to be very suitable for making blood bags because DEHP stabilizes red blood cells, minimizing hemolysis (red blood cell rupture). However, DEHP is coming under increasing pressure in Europe. The assessment of potential risks related to phthalates, and in particular the use of DEHP in PVC medical devices, was subject to scientific and policy review by the European Union authorities, and on 21 March 2010, a specific labeling requirement was introduced across the EU for all devices containing phthalates that are classified as CMR (carcinogenic, mutagenic or toxic to reproduction). The label aims to enable healthcare professionals to use this equipment safely, and, where needed, take appropriate precautionary measures for patients at risk of over-exposure Metal stabilizers BaZn stabilisers have successfully replaced cadmium-based stabilisers in Europe in many PVC semi-rigid and flexible applications. In Europe, particularly Belgium, there has been a commitment to eliminate the use of cadmium (previously used as a part component of heat stabilizers in window profiles) and phase out lead-based heat stabilizers (as used in pipe and profile areas) such as liquid autodiachromate and calcium polyhydrocummate by 2015. According to the final report of Vinyl 2010, cadmium was eliminated across Europe by 2007. The progressive substitution of lead-based stabilizers is also confirmed in the same document showing a reduction of 75% since 2000 and ongoing. This is confirmed by the corresponding growth in calcium-based stabilizers, used as an alternative to lead-based stabilizers, more and more, also outside Europe. Heat stabilizers Some of the most crucial additives are heat stabilizers. These agents minimize loss of HCl, a degradation process that starts above 70 °C (158 °F). Once dehydrochlorination starts, it is autocatalytic. Many diverse agents have been used including, traditionally, derivatives of heavy metals (lead, cadmium). Metallic soaps (metal "salts" of fatty acids) are common in flexible PVC applications, species such as calcium stearate. Properties PVC is a thermoplastic polymer. Its properties are usually categorized based on rigid and flexible PVCs. Notes Thermal and fire The