test for HERDA has been developed. Over 1,500 horses were tested during the development phase of the test, which is now available to the general public through both institutions. Glycogen Branching Enzyme Deficiency (GBED) is a genetic disease where the horse is lacking an enzyme necessary for storing glycogen, the horse's heart muscle and skeletal muscles cannot function, leading to rapid death. The disease occurs in foals who are homozygous for the lethal GBED allele, meaning both parents carry one copy of the gene. The stallion King P-234 has been linked to this disease. There is a DNA blood test for this gene. Equine polysaccharide storage myopathy, also called EPSM or PSSM, is a metabolic muscular condition in horses that causes tying up, and is also related to a glycogen storage disorder. While also seen in some draft horse breeds, PSSM has been traced to three specific but undisclosed bloodlines in Quarter Horses, with an autosomal recessive inheritance pattern. 48% of Quarter Horses with symptoms of neuromuscular disease have PSSM. To some extent it can be diet controlled with specialized low-starch diets, but genetic testing is advised before breeding, as the condition exists at a subclinical level in approximately 6% of the general Quarter Horse population. Lethal White Syndrome. Although "cropout" Quarter Horses with Paint markings were not allowed to be registered for many years, the gene for such markings is a recessive and continued to periodically appear in Quarter Horse foals. Thus, it is believed that some Quarter Horses may carry the gene for Lethal White Syndrome. There is a DNA test for this condition. Cleft Palate Birth defect, this is not just a genetic disorder. There is not just one thing that will cause this issue. It can be caused from genetics, hormones, mineral deficiency, tranquilizers, or steroids. Cleft palates are extremely uncommon. The surgery to repair the cleft palate does not have a high success rate. Only about a 20% success rate is seen from the surgery. Quarter horses seem to have the most research done with them, and this defect occurs more in quarter horses based on the research. Some observations of a horse with a cleft palate and no surgery are: lifting head high when eating, dropping head low to drink, coughing when beginning of exercise, and placing wormers or other oral medications in the side of the jaw and taking about hour to administer