being an extensional back-arc basin in the Mesozoic to being a compressional foreland basin in the Cenozoic. Volcanism The Andes range has many active volcanoes distributed in four volcanic zones separated by areas of inactivity. The Andean volcanism is a result of subduction of the Nazca Plate and Antarctic Plate underneath the South American Plate. The belt is subdivided into four main volcanic zones that are separated from each other by volcanic gaps. The volcanoes of the belt are diverse in terms of activity style, products and morphology. While some differences can be explained by which volcanic zone a volcano belongs to, there are significant differences inside volcanic zones and even between neighbouring volcanoes. Despite being a type location for calc-alkalic and subduction volcanism, the Andean Volcanic Belt has a large range of volcano-tectonic settings, such as rift systems and extensional zones, transpressional faults, subduction of mid-ocean ridges and seamount chains apart from a large range of crustal thicknesses and magma ascent paths, and different amount of crustal assimilations. Ore deposits and evaporates The Andes Mountains host large ore and salt deposits and some of their eastern fold and thrust belt acts as traps for commercially exploitable amounts of hydrocarbons. In the forelands of the Atacama Desert some of the largest porphyry copper mineralizations occur making Chile and Peru the first- and second-largest exporters of copper in the world. Porphyry copper in the western slopes of the Andes has been generated by hydrothermal fluids (mostly water) during the cooling of plutons or volcanic systems. The porphyry mineralization further benefited from the dry climate that let them largely out of the disturbing actions of meteoric water. The dry climate in the central western Andes has also led to the creation of extensive saltpeter deposits which were extensively mined until the invention of synthetic nitrates. Yet another result of the dry climate are the salars of Atacama and Uyuni, the first one being the largest source of lithium today and the second the world's largest reserve of the element. Early Mesozoic and Neogene plutonism in Bolivia's Cordillera Central created the Bolivian tin belt as well as the famous, now depleted, deposits of Cerro Rico de Potosí. History The Andes Mountains, initially inhabited by hunter-gatherers, experienced the development of agriculture and rise of politically centralised civilizations, which culminated in the establishment of the century-long Inca Empire. This all changed in the 16th century,