This measure, which was intended to diminish opposition, was paralleled by the introduction of new courtly dignities, like that of panhypersebastos given to Nikephoros Bryennios, or that of sebastokrator given to the emperor's brother Isaac Komnenos. Although this policy met with initial success, it gradually undermined the relative effectiveness of imperial bureaucracy by placing family connections over merit. Alexios' policy of integration of the nobility bore the fruit of continuity: every Byzantine emperor who reigned after Alexios I Komnenos was related to him by either descent or marriage. Family By his marriage with Irene Doukaina, Alexios I had the following children: Anna Komnene (1 December 1083 – 1148/55), in her infancy she was betrothed to Constantine Doukas, and with him treated as co-ruler by her father until after the birth of John II. In 1097 she married Nikephoros Bryennios the Younger, later raised to Caesar. Highly ambitious, after Alexios' death she tried unsuccessfully to usurp the throne. She then withdrew to a monastery, where she wrote her history of Alexios' reign. The couple had several children, but only four survived her. Maria Komnene (19 September 1085 – after 1136), initially betrothed to Gregory Gabras, but married to Nikephoros Katakalon. The couple had several children, but only two sons are known by name. John II Komnenos (13 September 1087 – 8 April 1143), who succeeded as emperor. Andronikos Komnenos (18 September 1091 – 1130/31), was named sebastokrator and participated in several campaigns until his death from disease. He married Irene, likely a Russian princess, and had at least two sons. Isaac Komnenos (16 January 1093 – after 1152), sebastokrator. Eudokia Komnene (14 January 1094 – c. 1129), who married the son of Constantine Iasites. Theodora Komnene (15 January 1096) who married (1) Constantine Kourtikes and (2) Constantine Angelos. By him she was the grandmother of Emperors Isaac II Angelos and Alexios III Angelos, as well as the progenitor of the ruling dynasty of the Despotate of Epirus. Through Isaac II's daughter Irene Angelina's children by Philip of Swabia, she is an ancestor of many European royal families, including all European monarchs currently reigning. Manuel Komnenos, born February 1097 and known only from a manuscript now in Moscow, died probably soon after his birth Zoe Komnene, born March 1098 and known only from a manuscript now in Moscow, died probably soon after her birth Later Russian sources also claim the existence of