began 60 years after Ashoka's rule ended, leading to the Hellenistic reconquest by the Greco-Bactrians. Much of it soon broke away from them and became part of the Indo-Greek Kingdom. They were defeated and expelled by the Indo-Scythians in the late 2nd century BCE. The Silk Road appeared during the first century BCE, and Afghanistan flourished with trade, with routes to China, India, Persia and north to the cities of Bukhara, Samarkand and Khiva in present-day Uzbekistan. Goods and ideas were exchanged at this center point, such as Chinese silk, Persian silver and Roman gold, while the region of present Afghanistan was mining and trading lapis lazuli stones mainly from the Badakhshan region. During the first century BCE, the Parthian Empire subjugated the region but lost it to their Indo-Parthian vassals. In the mid-to-late first century CE the vast Kushan Empire, centered in Afghanistan, became great patrons of Buddhist culture, making Buddhism flourish throughout the region. The Kushans were overthrown by the Sassanids in the 3rd century CE, though the Indo-Sassanids continued to rule at least parts of the region. They were followed by the Kidarites who, in turn, was replaced by the Hephthalites. They were replaced by the Turk Shahi in the 7th century. The Buddhist Turk Shahi of Kabul was replaced by a Hindu dynasty before the Saffarids conquered the area in 870, this Hindu dynasty was called Hindu Shahi. Much of the northeastern and southern areas of the country remained dominated by Buddhist culture. Medieval history Islamic conquest Arab Muslims brought Islam to Herat and Zaranj in 642 CE and began spreading eastward; some of the native inhabitants they encountered accepted it while others revolted. Before the arrival of Islam, the region used to be home to various beliefs and cults, often resulting in Syncretism between the dominant religions such as Zoroastrianism, Buddhism or Greco-Buddhism, Ancient Iranian religions, Hinduism, Christianity and Judaism. An exemplification of the syncretism in the region would be that people were patrons of Buddhism but still worshipped local Iranian gods such as Ahura Mazda, Lady Nana, Anahita or Mihr(Mithra) and portrayed Greek Gods like Heracles or Tyche as protectors of Buddha. The Zunbils and Kabul Shahi were first conquered in 870 CE by the Saffarid Muslims of Zaranj. Later, the Samanids extended their Islamic influence south of the Hindu Kush. It is reported that Muslims and non-Muslims still lived side by side in