Adolph Wilhelm Hermann Kolbe (27 September 1818 – 25 November 1884) was a major contributor to the birth of modern organic chemistry. He was a professor at Marburg and Leipzig. Kolbe was the first to apply the term synthesis in a chemical context, and contributed to the philosophical demise of vitalism through synthesis of the organic substance acetic acid from carbon disulfide, and also contributed to the development of structural theory. This was done via modifications to the idea of "radicals" and accurate prediction of the existence of secondary and tertiary alcohols, and to the emerging array of organic reactions through his Kolbe electrolysis of carboxylate salts, the Kolbe-Schmitt reaction in the preparation of aspirin and the Kolbe nitrile synthesis. After studies with Wöhler and Bunsen, Kolbe was involved with the early internationalization of chemistry through work in London (with Frankland). He was elected to the Royal Swedish Academy of Sciences, and won the Royal Society of London's Davy Medal in the year of his death. Despite these accomplishments and his training important members of the next generation of chemists (including Zaitsev, Curtius, Beckmann, Graebe, Markovnikov, and others), Kolbe is best remembered for editing the Journal für Praktische Chemie for more than a decade, in which his vituperative essays on Kekulé's structure of benzene, van't Hoff's theory on the origin of chirality and Baeyer's reforms of nomenclature were personally critical and linguistically violent. Kolbe died of a heart attack in Leipzig at age 66, six years after the death of his wife, Charlotte. He was survived by four children. Life Kolbe was born in Elliehausen, near Göttingen, Kingdom of Hanover (Germany) as the eldest son of a Protestant pastor. At the age of 13, he entered the Göttingen Gymnasium, residing at the home of one of the professors. He obtained the leaving certificate (the Abitur) six years later. He had become passionate about the study of chemistry, matriculating at the University of Göttingen in the spring of 1838 in order to study with the famous chemist Friedrich Wöhler. In 1842, he became an assistant to Robert Bunsen at the Philipps-Universität Marburg. He took his doctoral degree in 1843 at the same university. A new opportunity arose in 1845, when he became assistant to Lyon Playfair at the new Museum of Economic Geology in London and a close friend of Edward Frankland. From 1847, he was engaged in editing the Handwörterbuch