genome sequence, or combined top-down and bottom up approaches. Current technologies have the ability to assemble protein sequences with high accuracy by integrating de novo sequencing peptides, intensity, and positional confidence scores from database and homology searches. Antibody mimetic Antibody mimetics are organic compounds, like antibodies, that can specifically bind antigens. They consist of artificial peptides or proteins, or aptamer-based nucleic acid molecules with a molar mass of about 3 to 20 kDa. Antibody fragments, such as Fab and nanobodies are not considered as antibody mimetics. Common advantages over antibodies are better solubility, tissue penetration, stability towards heat and enzymes, and comparatively low production costs. Antibody mimetics have being developed and commercialized as research, diagnostic and therapeutic agents. Binding antibody unit BAU (binding antibody unit, often as BAU/mL) is a measurement unit defined by the WHO for the comparison of assays detecting the same class of immunoglobulins with the same specificity. See also Affimer Anti-mitochondrial antibodies Anti-nuclear antibodies Antibody mimetic Aptamer Colostrum ELISA Humoral immunity Immunology Immunosuppressive drug Intravenous immunoglobulin (IVIg) Magnetic immunoassay Microantibody Monoclonal antibody Neutralizing antibody Optimer Ligand Secondary antibodies Single-domain antibody Slope spectroscopy Synthetic antibody Western blot normalization References External links Mike's Immunoglobulin Structure/Function Page at University of Cambridge Antibodies as the PDB molecule of the month Discussion of the structure of antibodies at RCSB Protein Data Bank A hundred years of antibody therapy History and applications of antibodies in the treatment of disease at University of Oxford How Lymphocytes Produce Antibody from Cells Alive! Glycoproteins Immunology Reagents for biochemistry