restrictions on the production, import or use of GMO foods and crops. Currently a global treaty, the Biosafety Protocol, regulates the trade of GMOs. There is ongoing discussion regarding the labeling of foods made from GMOs, and while the EU currently requires all GMO foods to be labeled, the US does not. Herbicide-resistant seed has a gene implanted into its genome that allows the plants to tolerate exposure to herbicides, including glyphosate. These seeds allow the farmer to grow a crop that can be sprayed with herbicides to control weeds without harming the resistant crop. Herbicide-tolerant crops are used by farmers worldwide. With the increasing use of herbicide-tolerant crops, comes an increase in the use of glyphosate-based herbicide sprays. In some areas glyphosate resistant weeds have developed, causing farmers to switch to other herbicides. Some studies also link widespread glyphosate usage to iron deficiencies in some crops, which is both a crop production and a nutritional quality concern, with potential economic and health implications. Other GMO crops used by growers include insect-resistant crops, which have a gene from the soil bacterium Bacillus thuringiensis (Bt), which produces a toxin specific to insects. These crops resist damage by insects. Some believe that similar or better pest-resistance traits can be acquired through traditional breeding practices, and resistance to various pests can be gained through hybridization or cross-pollination with wild species. In some cases, wild species are the primary source of resistance traits; some tomato cultivars that have gained resistance to at least 19 diseases did so through crossing with wild populations of tomatoes. Environmental impact Effects and costs Agriculture is both a cause of and sensitive to environmental degradation, such as biodiversity loss, desertification, soil degradation and global warming, which cause decrease in crop yield. Agriculture is one of the most important drivers of environmental pressures, particularly habitat change, climate change, water use and toxic emissions. Agriculture is the main source of toxins released into the environment, including insecticides, especially those used on cotton. The 2011 UNEP Green Economy report stated that agricultural operations produced some 13 per cent of anthropogenic global greenhouse gas emissions. This includes gases from the use of inorganic fertilizers, agro-chemical pesticides, and herbicides, as well as fossil fuel-energy inputs. Agriculture imposes multiple external costs upon society through effects such as pesticide damage to nature (especially herbicides and insecticides), nutrient runoff, excessive water usage, and loss of natural environment.